CROHN’S DISEASE ULCERATIVE COLITIS

DIFFERENCES
 Affects small and large intestines  Affects large intestines only

 Mucus lining of the large intestine is

 Ulceration is deeper and may extend into
ulcerated. These ulcers do not extend
all the layers of the bowel wall.
beyond this inner lining

 Pain in the lower left part of the

 Pain in the lower right abdomen
abdomen

 Bleeding from the rectum during bowel

 Bleeding is much less common
movements is very common

 Cause: unknown  Cause: unknown

 Pattern of inflammation: begins in the

 Pattern of Inflammation: tends to be
rectum or sigmoid colon, and spreads up
continuous throughout the inflamed
through the colon as the disease
areas
progresses

 Appearance: colon wall may be

 Appearance: the colon wall is thinner
thickened and, because of the
and shows continuous inflammation
intermittent pattern of diseased and
with no patches of healthy tissue in the
healthy tissue, may have a "cobblestone"
diseased section.
appearance

 It may affect any age group, although

 Most people with Crohn’s disease are
there are peaks at ages 15 - 30 and then
diagnosed between the ages of 15 to 35
again at ages 50 - 70.

 Most common symptoms: abdominal  evere abdominal pain, intense diarrhea,

pain and diarrhea and high fever

 Granulomas are present  Granulomas are not present

 Associated with non smokers or ex

 Strongly associated with smoking
smokers