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Lec 2 - SFSel - MemCell - 6-9sep17 PDF
Lec 2 - SFSel - MemCell - 6-9sep17 PDF
K10
A eukaryotic cell
has organelles
within the
cytoplasm whose
interiors are
separated from
the cytosol by
membranes
K10
Comparing Prokaryotic and Eukaryotic Cells Contd
K10
2. The eukaryotic cells genetic instructions are housed
in the nucleus and carried out by the ribosomes
K10
Function?
The ER membrane is
continuous with the
nuclear envelope ER lumen
Cisternae
There are two distinct Ribosomes
Transitional ER
Transport vesicle
regions of ER: Smooth ER Rough ER
200 nm
cis face
(receiving side of 0.1 m
Golgi apparatus)
Cisternae
trans face
(shipping side of TEM of Golgi apparatus
Golgi apparatus)
Mitochondrion
fragment
Peroxisome
fragment
Lysosome
Digestive
enzymes
Lysosome Lysosome
Plasma Peroxisome
membrane
Digestion
Central vacuole
Cytosol
Nucleus Central
vacuole
Cell wall
Chloroplast
5 m
Intermembrane space
Outer
membrane
Free
ribosomes
in the
mitochondrial
matrix Inner
membrane
Cristae
Matrix
0.1 m
Ribosomes
Stroma
Granum
1 m
Thylakoid
Plasmodesmata
K16
The Extracellular Matrix (ECM) of Animal Cells
Fibronectin Core
protein
Integrins
Proteoglycan
molecule
Plasma
membrane
Proteoglycan
complex
Micro- CYTOPLASM
filaments
K16
Intercellular Junctions
K16
Plasmodesmata in Plant Cells
Cell walls
Interior
of cell
Interior
of cell
0.5 m Plasmodesmata Plasma membranes
Tight Junctions,
Desmosomes, and
0.5 m
Gap Junctions in
Animal Cells Tight junction
Intermediate
filaments
Desmosome
Gap Desmosome 1 m
junctions
Extracellular
Space matrix
between Gap junction
cells
Plasma membranes
of adjacent cells 0.1 m
K16
At tight junctions, membranes of Tight junctions prevent
fluid from moving
across a layer of cells
K16
Membrane Structure and
Function I (Ch. 7)
Hydrophobic Hydrophilic
regions regions of
of protein protein
WATER
Hydrophilic
head
Hydrophobic
tail
WATER
K18: Students shoiuld be able to explain influence of temperature and membrane composition on
its fluidity
Membrane Proteins and Their Functions
Fibers of
extracellular
matrix (ECM)
Glyco- Carbohydrate
protein
Glycolipid
EXTRACELLULAR
SIDE OF
MEMBRANE
Cholesterol
Microfilaments Peripheral
of cytoskeleton proteins
Integral
protein
CYTOPLASMIC SIDE
OF MEMBRANE
K19: Students should be able to differentiate integral proteins from peripheral proteins; and their
functions
Six major
functions of
membrane
proteins
K19
K19
Summary
1. Eukaryotic cells have internal membranes that
compartmentalize their function
2. The eukaryotic cells generic instructions are housed in
the nucleus and carried out by the ribosomes
3. The endomembrane system regulate protein traffic
and performs metabolic functions in the cell
4. Mitochondria and chloroplasts change energy from
one form to another
5. Extracellular components and connections between
cells help coordinate cellular activities
6. Cellular membranes are fluid mosaics of lipids and
proteins
Next Week
Lecture Topics
(1) Membrane Structure and Function II;
(2) An Introduction to Metabolism
Read Chapter 7 and 8 before class
Quiz 1 covering Cell structure and function, as
well as Metabolism