Salacia Oblonga

What Is Salacia oblonga, used for today?

Since the late 1990's, Salacia oblonga has undergone modern research, which to some extent is
very preliminary, it substantiated its traditional reputation as a treatment for diabetes and
obesity.

Salacia Oblonga may work similarly to the standard diabetes drug acarbose, used in type 2
diabetes. Acarbose inhibits intestinal enzyme alpha-glucosidase, the enzyme responsible for
digesting carbohydrates helps. When Alpha-glucosidase is inhibited, it slows the absorption of
carbohydrates, thereby reducing blood sugar level, which follows the meal.

In a double-blind, placebo-controlled study published in 2005 evaluated the effects of S.

oblonga extract taken at a dose of 1000 mg daily. In this study, 43 healthy subjects were high
carbohydrate drink with or without grass. The results showed that when the plant extract
was included, a normal blood sugar and insulin levels after consumption of the beverage has
been significantly reduced. Additional evidence obtained in this study (breath hydrogen
levels), supporting the hypothesis that S. oblonga works by inhibiting alpha-glucosidase.

Another double-blind study to compare the efficacy of different doses of salacia oblonga
extract: 0, 500, 700 or 1000 mg daily. Again, the participants gave a high carbohydrate
beverage. The results of these 39 people showed that high dose but not at lower doses,
significantly improved post-prandial blood sugar and insulin levels. This type of "dose-
dependent" effect, where higher doses have a greater effect, tends to increase the
confidence researchers can place in the results of the study.

However, none of these studies involved people with diabetes. Further studies will be needed
to actually determine whether S. oblonga useful for treatment of people with this condition.

About Side Effects

Salacia oblonga is considered to be relatively safe. Some evidence suggests that Salacia oblonga
does not damage DNA. Studies in rats have shown a good safety profile. In human studies, the
main side effects are identical to the standard side effects of alpha-glucosidase inhibitors: gas
and cramping. Maximum safe dosages are not known pregnant or nursing women, or people
with severe liver or kidney disease.
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