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BIOC302Syl 08
BIOC302Syl 08
BIOC302Syl 08
OFFICE HOURS: Monday – Friday, 12:00 noon to 1:00 pm (or other hours by appointment)
REQUIRED TEXT: Lehninger Principles of Biochemistry, Fourth Edition, D.L. Nelson and M.M. Cox,
Freeman and Company, Inc., New York, 2005
OPTIONAL SUPPLEMENT: The Absolute, Ultimate Guide to Lehninger Principles of Biochemistry Study
Guide and Solutions Manual, DM. Osgood and K Ocorr, Freeman and
Company, Inc., New York, 2005
GRADING: Grades will be determined by points earned on: a) exams; b) quizzes; c) class discussions of
problems or other contributions to class discussions; and d) oral reports on review articles relevant to
metabolism:
Regular exams (3 at 100 points each) 300
Comprehensive final exam 100
Quizzes (5 highest scores of six 10 pt quizzes) 50
Problem discussions/class contributions 50
Oral reports of review articles 50
Total 550
Course letter grades will be assigned based on the percentage of total points earned:
90-100% = A 80-89% = B 70-79% = C 60-69% = D <60% = F
EXAMS
The exams will be composed of short answer questions, essay-type questions, and problems generally
similar to the end-of-chapter problems. Exam items may be drawn from readings, lectures, or student
oral presentations of review articles. The tentative dates for the exams are given in the schedule at the
end of the syllabus.
The final exam will be comprehensive. A portion of the final will be based on topics covered since
the last regular exam. The rest of the exam will address important topics from any point in the course
and may require integration of material from throughout the course. The final exam is scheduled for
Wednesday, May 1, 8:00 am-10:00 am.
QUIZZES
There will be six quizzes during the semester. The quizzes are described under “Learning Strategies
for Biochemistry” on the course website. Each quiz will be announced (in class or by email) at least one
week in advance. The objective of the quizzes is to encourage you to complete important memorization
work as we begin the examination of various metabolic topics. Each quiz is worth a total of 10 points
(1/10 of an exam). The five highest quiz grades will be added to give the total points earned on quizzes.
Any changes will be announced as soon as possible. Changes in exam dates or topics will
be announced at least one week in advance of the actual exam date.
Class
Dates Topic/Activity Reading
meeting
syllabus, Text pp. 481-488
1 Jan 15 Intro to course & metabolism “Learning Strategies for
Biochemistry” (see course website)
2, 3 Jan 17, 22 Principles of bioenergetics Chapter 13
4, 5 Jan 24, 29 Glucose pathways Chapter 14
6, 7 Jan 31, Feb 5 Principles of metabolic regulation Chapter 15
8 Feb 7 catch-up/review
9 Feb 12 Exam #1: Chapters 13-15
10, 11 Feb 14, 19 Pryuvate dehyrogenase & citric acid cycle Chapter 16
12, 13 Feb 21, 26 Fatty acid catabolism Chapter 17
14, 15 Feb 28, Mar 4 Amino acid oxidation & urea cycle Chapter 18
16 Mar 6 Exam #2: Chapters 16-18
Spring Break
17, 18 Mar 18, 20 Oxidative phosphorylation Chapter 19 through 19.5
Photophosphorylation 19.6 to end of chapter 19
19 Mar 25
Carbohydrate synthesis in bacteria and plants Chapter 20 through 20.1
20 Mar 27 Lipid biosynthesis Chapter 21 (omit 21.2 & 21.3)
Chapter 22 (selected topics to be
21 Apr 1 Biosynthesis of amino acids and nucleotides
determined)
22 Apr 3 catch-up/review
23 Apr 8 Exam #3: Chapters 19-22
24 April 10 Integration & hormonal regulation of metabolism Chapter 23
25 April 15 Review article presentations 1-4
26 April 17 Review article presentations 5-8
27 April 22 Review article presentations 9-12
28 April 24 Review article presentations 13 & 14
29 May 1 Final exam (8:00 am – 10:00 am)