DRUG ANALYSIS

Generic Name Brand Names Indication for the Mechanism of action Nursing
patient Responsibilities
Sterofundin Iso Sterofundin ISO It is used as It works by providing extra Check for the
Solution replacement of calcium to the body; preventing prescribed dose.
extracellular fluid low amount of magnesium in the Patient receiving more
losses in the case of blood; dissociating the malic than the prescribed
isotonic dehydration acid in H+, which they join water doze will not improve
perioperative, to become hydronium ions the symptoms
where acidosis is (H3O+); This action produces a Assess for side
present or imminent. salivary secretion stimulation to effects: Constipation
dilute the concentration of acids Headache
in the buccal cavity; works for Loss Of Appetite
nerve conduction, muscle Nausea
contraction, kidney function and Vomiting
heart beating; increasing the Depression
blood volume; possessing the Check IV site for signs
sodium chloride content. of swelling, redness,
etc.
 Generic Name Brand Names Indication for the Mechanism of action Nursing
patient Responsibilities
Multivitamins Centrum, Myrevit, It strengthens the Advise to take
Cherifer PGM immune system, thus multivitamins by
increasing overall body mouth with or
resistance to stress and without food. If
infections, enhances stomach upset
appetite, provides occurs, take with
Recommended Energy food to reduce
and Nutrient Intakes of stomach irritation.
the vitamin A and B-, Advise not to miss a
maximizes metabolism dose of
and utilization of multivitamins. If it
carbohydrates, proteins
and fats.
Inform for possible
happens, take it as
soon as possible. If
it is almost time for
your next dose, skip
the missed dose
and go back to your
regular dosing
schedule. Advise
not to take 2 doses
at once.
adverse effects:
Severe allergic
reactions (swelling,
difficulty of
breathing, rashes)
 Generic Name Brand Names Indication for the patient Mechanism of action Nursing
Responsibilities
Omeprazole Prilosec, Zegerid It is used to suppress gastric It is an antisecretory compound Monitor urinalysis for
acid secretion relieving that is a gastric acid pump hematuria and
gastrointestinal distress inhibitor. It inhibits gastric acid proteinuria.
secretion by inhibiting the H+, Advice patient to
K+-ATPase enzyme system in report any changes in
the parietal cells. urinary elimination
such as pain or
discomfort associated
with urination, or
blood in urine.
Monitor for severe
diarrhea; drug may
need to be
discontinued.
Give medication
before meals,
preferably in the
 morning for once-
daily dosing. If
necessary, also give
an antacid, as
prescribed.
Encourage patient to
avoid alcohol, aspirin
products, ibuprofen,
and foods that may
increase gastric
secretions during
therapy.
 GENERIC NAME BRAND NAMES INDICATION MECHANISM OF ACTION
Ranitidine Zantac , Nu-ranit short treatment of Ranitidine competitively
hydrochloride IV peptic ulcer blocks histamine at H2-
receptors of the gastric
parietal cells which inhibits
gastric acid secretion. It does
not affect pepsin secretion,
pentagastrin-stimulated
intrinsic factor secretion or
serum gastrin.
NURSING RESPONSIBILITES
Monitor for side
effects:constipation or diarrhea ,
nausea, vomiting; headache.
Report sore throat, fever, unusual
bruising or bleeding, tarry stools,
confusion, hallucinations,
dizziness, severe headache,
muscle or joint pain.
Be alert for early signs of
hepatotoxicity: jaundice
Monitor serum ALT concentrations
daily; gastric pH and renal
function.
Ampicillin UNASYN Indicated for surgical The beta-lactamase inhibitors Administer IV dose over at least
sulbactam IV Ampimax prophylaxis, are recognized as substrates 10 to 15 min, or further dilute
abdominal procedure for the beta-lactamases solution and administer over 15 to
to reduce wound produced by bacteria. This 30 min. Rapid IV administration
infections allows the actual beta- may cause seizures.
lactams to attack the
bacterial cell wall by binding Check IV site carefully for signs of
to penicillin binding proteins thrombosis or drug reaction.

Monitor side effects: Nausea,

Ampicillin is a penicillin
antibiotic. It works by killing
sensitive bacteria by
interfering with formation of
the bacteria's cell wall while it
is growing. This weakens the
cell wall and it ruptures,
resulting in the death of the
bacteria.
vomiting, diarrhea.
Report pain or discomfort at sites,
unusual bleeding or bruising,
mouth sores, rash, hives, fever,
itching, severe diarrhea, difficulty
breathing.

Sulbactam blocks the

enzyme which breaks down
ampicillin and thereby allows
ampicillin to attack and kill
the bacteria.

Ampicillin without sulbactam

is not effective against beta-
lactamase producing strains.
Castor oil Neoloid, Purge To clean out the It works by increasing the Drink fluids as directed to prevent
intestines for bowel movement of the intestines, dehydration.
preparation for helping the stool to come out.
diagnostic tests. The action is quick, within 2 to 6
Acts on the small bowel and hours, so the laxative should not
Castor oil is known as produces a watery stool. be taken at bedtime.
a stimulant laxative
(purgative).
Dulcolax Bisacodyl Bisacodyl is a Stimulates peristalsis by
stimulant laxative for directly irritating the smooth
bowel evacuation muscle of the intestine,
before investigational possibly the colonic
procedures or intramural plexus; alters
surgery. water and electrolyte
secretion producing net
intestinal fluid accumulation
and laxation
Retain for 1520 minutes. Results
usually within 15 minutes to 1
hour; reevaluate if ineffective.
Advise fluid intake at least 68
glasses.
Evaluate periodically patient's
need for continued use of drug;
bisacodyl usually produces 1 or 2
soft formed stools daily.
do not take within at least 1 hour
after antacids or milk.
Report signs of abdominal
discomfort, faintness, cramps;
also supps: rectal burning.