Table of Contents

<hr>SECTION 1: Foundation Issues<br>Section Editor: L. Michael Posey

1. Pharmacoeconomics: Principles, Methods, and Applications<br> Lisa Sanchez Trask
2. Health Outcomes and Health-Related Quality of Life<br> Stephen Joel Coons
3. Health Literacy and Medication Use<br> Oralia V. Bazaldua and Sunil Kripalani
4. Cultural Competency<br> Jeri J. Sias, Amanda M. Loya, José O. Rivera, Arthur A. Islas, and
Ulysses J. Urquidi
5. Principles and Practices of Medication Safety<br> Scott M. Mark, Jeffrey D. Little, Sarah E.
Adkins, and Robert J. Weber
6. Evidence-Based Medicine<br> Elaine Chiquette and L. Michael Posey
7. Documentation of Pharmacy Services<br> George E. MacKinnon III and Neil J. MacKinnon
8. Clinical Pharmacokinetics and Pharmacodynamics<br> Larry A. Bauer
9. Pharmacogenetics<br> Larisa H. Cavallari and Y. W. Francis Lam
10. Pediatrics<br> Milap C. Nahata and Carol Taketomo
11. Geriatrics<br> Emily R. Hajjar, Shelly L. Gray, David R.P. Guay, Catherine I. Starner, Steven
M. Handler, and Joseph T. Hanlon
12. Palliative Care<br> Jill Astolfi
13. Pharmacoepidemiology<br> Andy Stergachis, Thomas K. Hazlet, and Denise Boudreau
14. Clinical Toxicology<br> Peter A. Chyka
15. Emergency Preparedness: Identification and Management of Biologic Exposures<br> Colleen
M. Terriff, Jason E. Brouillard, Lisa T. Costanigro, and Jessica S. Oftebro
16. Emergency Preparedness: Identification and Management of Chemical and Radiologic
Exposures<br> Greene Shepherd and Richard B. Schwartz
<hr>SECTION 2: Cardiovascular Disorders<br>Section Editor: Robert L. Talbert
17. Cardiovascular Testing<br> Richard A. Lange and L. David Hillis
18. Cardiac Arrest<br> Jeffrey F. Barletta and Jeffrey L. Wilt
19. Hypertension<br> Joseph J. Saseen and Eric J. Maclaughlin
20. Systolic Heart Failure<br> Robert B. Parker and Larisa H. Cavallari
21. Diastolic Heart Failure and the Cardiomyopathies<br> Jean M. Nappi and Robert L. Page II
22. Acute Decompensated Heart Failure<br> Jo E. Rodgers and Craig R. Lee
23. Ischemic Heart Disease<br> Robert L. Talbert
24. Acute Coronary Syndromes<br> Sarah A. Spinler and Simon De Denus
25. The Arrhythmias<br> Cynthia A. Sanoski and Jerry L. Bauman
26. Venous Thromboembolism<br> Daniel M. Witt, Edith A. Nutescu, and Stuart T. Haines
27. Stroke<br> Susan C. Fagan and David C. Hess
28. Dyslipidemia<br> Robert L. Talbert
29. Peripheral Arterial Disease<br> Barbara J. Hoeben and Robert L. Talbert
30. Use of Vasopressors and Inotropes in the Pharmacotherapy of Shock<br> Robert Maclaren,
Maria I. Rudis, and Joseph F. Dasta
31. Hypovolemic Shock<br> Brian L. Erstad
<hr>SECTION 3: Respiratory Disorders<br>Section Editor: Robert L. Talbert
32. Introduction to Pulmonary Function Testing<br> Jay I. Peters and Stephanie M. Levine
33. Asthma<br> H. William Kelly and Christine A. Sorkness
34. Chronic Obstructive Pulmonary Disease<br> Dennis M. Williams and Sharya V. Bourdet
35. Pulmonary Arterial Hypertension<br> Rebecca Moote, Rebecca L. Attridge, and Deborah J.
Levine
36. Drug-Induced Pulmonary Disease<br> Hengameh H. Raissy, Michelle Harkins, and Patricia L.
Marshik
37. Cystic Fibrosis<br> Chanin C. Wright and Yolanda Y. Vera
<hr>SECTION 4: Gastrointestinal Disorders<br>Section Editor: Joseph T. DiPiro
38. Evaluation of the Gastrointestinal Tract<br> Keith M. Olsen and Grant F. Hutchins
39. Gastroesophageal Reflux Disease<br> Dianne B. Williams and Robert R. Schade
40. Peptic Ulcer Disease<br> Rosemary R. Berardi and Randolph V. Fugit
41. Inflammatory Bowel Disease<br> Brian A. Hemstreet
42. Nausea and Vomiting<br> Cecily V. DiPiro and Robert J. Ignoffo
43. Diarrhea, Constipation, and Irritable Bowel Syndrome <br> Patricia H. Powell and Virginia H.
Fleming
44. Portal Hypertension and Cirrhosis<br> Julie M. Sease
45. Drug-Induced Liver Disease<br> William R. Kirchain and Rondall E. Allen
46. Pancreatitis<br> Scott Bolesta and Patricia A. Montgomery
47. Viral Hepatitis<br> Paulina Deming
48. Drug Therapy Individualization in Patients with Hepatic Disease and Genetic Alterations in
Drug Metabolizing Activity<br> Y. W. Francis Lam
49. Celiac Disease<br> Robert A. Mangione and Priti N. Patel
<hr>SECTION 5: Renal Disorders<br>Section Editor: Gary R. Matzke
50. Clinical Assessment of Kidney Function<br> Thomas C. Dowling
51. Acute Kidney Injury<br> William Dager and Jenana Halilovic
52. Chronic Kidney Disease: Progression-Modifying Therapies<br> Vimal K. Derebail, Abhijit V.
Kshirsagar, and Melanie S. Joy
53. Chronic Kidney Disease: Management of Complications<br> Joanna Q. Hudson
54. Hemodialysis and Peritoneal Dialysis<br> Kevin M. Sowinski and Mariann D. Churchwell
55. Drug-Induced Kidney Disease<br> Thomas D. Nolin and Jonathan Himmelfarb
56. Glomerulonephritis<br> Alan H. Lau
57. Drug Therapy Individualization for Patients with Chronic Kidney Disease<br> Gary R. Matzke
58. Disorders of Sodium and Water Homeostasis<br> James D. Coyle and Gary R. Matzke
59. Disorders of Calcium and Phosphorus Homeostasis<br> Amy Barton Pai
60. Disorders of Potassium and Magnesium Homeostasis<br> Donald F. Brophy and Jane Frumin
61. Acid-Base Disorders<br> John W. Devlin and Gary R. Matzke
<hr>SECTION 6: Neurologic Disorders<br>Section Editor: Barbara G. Wells
62. Evaluation of Neurologic Illness<br> Susan C. Fagan and Fenwick T. Nichols
63. Alzheimer’s Disease<br> Patricia W. Slattum, Russell H. Swerdlow, and Angela Massey Hill
64. Multiple Sclerosis<br> Jacquelyn L. Bainbridge and John R. Corboy
65. Epilepsy<br> Susan J. Rogers and Jose E. Cavazos
66. Status Epilepticus<br> Stephanie J. Phelps, Collin A. Hovinga, and James W. Wheless
67. Acute Management of the Brain Injury Patient<br> Bradley A. Boucher and Shelly D. Timmons
68. Parkinson’s Disease<br> Jack J. Chen, Merlin V. Nelson, and David M. Swope
69. Pain Management<br> Terry J. Baumann, Jennifer M. Strickland, and Chris M. Herndon
70. Headache Disorders<br> Deborah S. Minor
<hr>SECTION 7: Psychiatric Disorders<br>Section Editor: Barbara G. Wells
71. Evaluation of Psychiatric Illness<br> Mark E. Schneiderhan, Leigh Anne Nelson, and Stuart
Munro
72. Childhood Disorders<br> Julie A. Dopheide and Stephen R. Pliszka
73. Eating Disorders<br> Steven C. Stoner
74. Substance-Related Disorders: Overview and Depressants, Stimulants, and Hallucinogens<br>
Paul L. Doering
75. Substance-Related Disorders: Alcohol, Nicotine, and Caffeine<br> Paul L. Doering and Robin
Moorman Li
76. Schizophrenia<br> M. Lynn Crismon, Tami R. Argo, and Peter F. Buckley
77. Major Depressive Disorder<br> Christian J. Teter, Judith C. Kando, and Barbara G. Wells
78. Bipolar Disorder<br> Shannon J. Drayton
79. Anxiety Disorders I: Generalized Anxiety, Panic, and Social Anxiety Disorders<br> Sarah T.
Melton and Cynthia K. Kirkwood
80. Anxiety Disorders II: Posttraumatic Stress Disorder and Obsessive-Compulsive Disorder<br>
Cynthia K. Kirkwood, Lisa B. Phipps, and Barbara G. Wells
81. Sleep Disorders<br> John M. Dopp and Bradley G. Phillips
82. Disorders Associated with Intellectual Disabilities<br> Nancy Brahm, Jerry Mckee, and
Douglas Stewart
<hr>SECTION 8: Endocrinologic Disorders<br>Section Editor: Robert L. Talbert
83. Diabetes Mellitus<br> Curtis L. Triplitt and Charles A. Reasner
84. Thyroid Disorders<br> Jacqueline Jonklaas and Robert L. Talbert
85. Adrenal Gland Disorders<br> Steven M. Smith and John G. Gums
86. Pituitary Gland Disorders<br> Amy Heck Sheehan, Jack A. Yanovski, and Karim Anton Calis
<hr>SECTION 9: Gynecologic and Obstetric Disorders<br>Section Editor: Barbara G. Wells
87. Pregnancy and Lactation: Therapeutic Considerations<br> Kristina E. Ward and Barbara M.
O’Brien
88. Contraception<br> Sarah P. Shrader, Kelly R. Ragucci, and Vanessa A. Diaz
89. Menstruation-Related Disorders<br> Elena M. Umland, Lara Carson Weinstein, and Edward
M. Buchanan
90. Endometriosis<br> Deborah A. Sturpe
91. Hormone Therapy in Women<br> Sophia N. Kalantaridou, Devra K. Dang, Susan R. Davis,
and Karim Anton Calis
<hr>SECTION 10: Urologic Disorders<br>Section Editor: L. Michael Posey
92. Erectile Dysfunction<br> Mary Lee
93. Benign Prostatic Hyperplasia<br> Mary Lee
94. Urinary Incontinence<br> Eric S. Rovner, Jean Wyman, Thomas Lackner, and David R.P. Guay
<hr>SECTION 11: Immunologic Disorders<br>Section Editor: Gary C. Yee
95. Function and Evaluation of the Immune System<br> Philip D. Hall, Nicole Weimert Pilch, and
Daniel H. Atchley
96. Systemic Lupus Erythematosus and Other Collagen-Vascular Disorders<br> Jeffrey C.
Delafuente and Kimberly A. Cappuzzo
97. Allergic and Pseudoallergic Drug Reactions <br> Lynne M. Sylvia and Joseph T. DiPiro
98. Solid-Organ Transplantation<br> Heather J. Johnson and Kristine S. Schonder
<hr>SECTION 12: Rheumatologic Disorders<br>Section Editor: L. Michael Posey
99. Osteoporosis and Other Metabolic Bone Diseases<br> Mary Beth O’Connell and Sheryl F.
Vondracek
100. Rheumatoid Arthritis<br> Arthur A. Schuna
101. Osteoarthritis<br> Lucinda M. Buys and Mary Elizabeth Elliott
102. Gout and Hyperuricemia<br> Michael E. Ernst and Elizabeth C. Clark
<hr>SECTION 13: Ophthalmic and Otolaryngological Disorders<br>Section Editor: L.
Michael Posey
103. Glaucoma<br> Richard G. Fiscella, Timothy S. Lesar, and Deepak P. Edward
104. Allergic Rhinitis<br> J. Russell May and Philip H. Smith
<hr>SECTION 14: Dermatologic Disorders<br>Section Editor: L. Michael Posey
106. Acne Vulgaris<br> Debra J. Sibbald
107. Psoriasis<br> Rebecca M. Law and Wayne P. Gulliver
108. Atopic Dermatitis<br> Rebecca M. Law and Po Gin Kwa
<hr>SECTION 15: Hematologic Disorders<br>Section Editor: Gary C. Yee
109. Anemias<br> Kristen Cook, Beata A. Ineck, and William L. Lyons
110. Coagulation Disorders<br> Betsy Bickert Poon, Char Witmer, and Jane Pruemer
111. Sickle Cell Disease<br> C. Y. Jennifer Chan and Reginald Moore
112. Drug-Induced Hematologic Disorders<br> Christine N. Hansen and Amy F. Rosenberg
<hr>SECTION 16: Infectious Diseases<br>Section Editor: Joseph T. DiPiro
113. Laboratory Tests to Direct Atimicrobial Pharmacotherapy<br> Michael J. Rybak, Jeffrey R.
Aeschlimann, and Kerry L. Laplante
114. Antimicrobial Regimen Selection<br> David S. Burgess
115. Central Nervous System Infections<br> Isaac F. Mitropoulos, Elizabeth D. Hermsen, and John
C. Rotschafer
116. Lower Respiratory Tract Infections<br> Martha G. Blackford, Mark L. Glover, and Michael D.
Reed
117. Upper Respiratory Tract Infections<br> Christopher Frei, Bradi Frei, and George Zhanel
118. Influenza<br> Jessica C. Njoku and Elizabeth D. Hermsen
119. Skin and Soft-Tissue Infections<br> Douglas N. Fish, Susan L. Pendland, and Larry H.
Danziger
120. Infective Endocarditis<br> Angie Veverka and Michael A. Crouch
121. Tuberculosis<br> Charles A. Peloquin and Rocsanna Namdar
122. Gastrointestinal Infections and Enterotoxigenic Poisonings<br> Steven Martin and Rose Jung
123. Intraabdominal Infections<br> Joseph T. DiPiro and Thomas R. Howdieshell
124. Parasitic Diseases<br> J. V. Anandan
125. Urinary Tract Infections and Prostatitis<br> Elizabeth A. Coyle and Randall A. Prince
126. Sexually Transmitted Diseases<br> Leroy C. Knodel
127. Bone and Joint Infections<br> Edward P. Armstrong and Allan D. Friedman
128. Severe Sepsis and Septic Shock<br> S. Lena Kang-Birken and Karla Killgore-Smith
129. Superficial Fungal Infections<br> Thomas E. R. Brown, Linda D. Dresser, and Thomas W. F.
Chin
130. Invasive Fungal Infections<br> Peggy L. Carver
131. Infections in Immunocompromised Patients<br> Douglas N. Fish
132. Antimicrobial Prophylaxis in Surgery<br> Salmaan Kanji
133. Vaccines, Toxoids, and Other Immunobiologics<br> Mary S. Hayney
134. Human Immunodeficiency Virus Infection <br> Peter L. Anderson, Thomas N. Kakuda, and
Courtney V. Fletcher
<hr>SECTION 17: Oncologic Disorders<br>Section Editor: Gary C. Yee
135. Cancer Treatment and Chemotherapy<br> Patrick J. Medina and Stacy S. Shord
136. Breast Cancer<br> Laura Boehnke Michaud, Chad M. Barnett, and Francisco J. Esteva
137. Lung Cancer <br> Deborah A. Frieze and Val R. Adams
138. Colorectal Cancer <br> Lisa E. Davis, Weijing Sun, and Patrick J. Medina
139. Prostate Cancer<br> LeAnn B. Norris and Jill M. Kolesar
140. Lymphomas <br> Alexandre Chan and Gary C. Yee
141. Ovarian Cancer<br> Judith A. Smith and Judith K. Wolf
142. Acute Leukemias<br> Betsy Bickert Poon and Dianne M. Brundage
143. Chronic Leukemias<br> Christopher A. Fausel and Patrick J. Kiel
144. Multiple Myeloma <br> Timothy R. McGuire and Casey B. Williams
145. Myelodysplastic Syndromes<br> Julianna A. Burzynski and Tracey Walsh-Chocolaad
146. Renal Cell Carcinoma <br> Christine M. Walko, Ninh M. La-Beck, and Mark D. Walsh
147. Melanoma <br> Cindy L. O’Bryant and Jamie C. Poust
<hr>SECTION 18: Nutritional Disorders<br>Section Editor: Gary R. Matzke
149. Assessment of Nutrition Status, and Nutrition Requirements<br> Katherine Hammond
Chessman and Vanessa J. Kumpf
150. Medication Administration Considerations with Specialized Nutrition Support<br> Roland N.
Dickerson and Gordon S. Sacks
151. Parenteral Nutrition<br> Todd W. Mattox and Catherine M. Crill
152. Enteral Nutrition<br> Vanessa J. Kumpf and Katherine Hammond Chessman
153. Nutritional Considerations in Major Organ Failure<br> Brian M. Hodges and Mark DeLegge
154. Obesity<br> Judy T. Chen, Amy Heck Sheehan, Jack A. Yanovski, and Karim Anton Calis
148. Hematopoietic Stem Cell Transplantation <br> Janelle B. Perkins and Gary C. Yee