Professional Documents
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Po Related To PTHR Protien (Lung Ca, RCC, Pheochromocytoma)
Po Related To PTHR Protien (Lung Ca, RCC, Pheochromocytoma)
Po Related To PTHR Protien (Lung Ca, RCC, Pheochromocytoma)
↑ or N PTH
↓ PTH
1⁰ HyperPTH
2⁰ HyperPTH
Drug Induced
↑ or N PO4
Immobilization
Milk alkalli syndrome (Hypercalcemia
with alkalosis and renal failure)
Granulomatous disease i.e. TB. sarcoid,
Drugs: thiazide diuretics, CaC03, Hypervitaminosis D:
lymphoma (esp Hodgkins) which causes extra
theophylline, estrogen/tamoxifen excessive intake of vit
renal production of calcitriol by macrophages in
Metastatic bone disease i.e. breast Ca D or its metabolites
the lung and lymph nodes Excessive calcitriol
which is mediated by Osteoclast intake
Activating Factor (OAF) and various
cytokines
High bone turnover i.e. hypervitaminosis
A, thyrotoxicosis, Paget's Disease