TruSpine Technologies Limited

Investor update
January 2018

Fundraising

After a slow start, due in part to market conditions, Brexit concerns, and changes in legislation for
pension related investments, the company saw a welcome increase in equity investment from
several funding sources. The most significant of which came from AIM listed investing company
Primorus Investments Plc, who invested £500K in a placing late last summer.

This year the company has already secured further funding through a placing that closed at the end
of January, from which the funds are imminently expected to arrive. This clearly illustrates a
continued high degree of confidence in the company and its products.

The company intends to secure up to a further $1.5m USD in order to fully fund it to its first FDA
clearance, and subsequent planned IPO.

Product Development & IP

There have been additional Intellectual Property filings/publications, including regular updates to
incorporate all additional design modifications and nuances, and as a result the company’s IP
position is considered by the patent attorneys to be extremely robust. Once again this process
continues to illustrate the validity of the unique and disruptive attributes of the company’s products.

Significant recent filings/publications include;

1. Provisional Application for CerviFAS dated Nov 30th 2017

2. Notice of publication for FaciLOK dated Nov 9th 2017

Final development and testing of the FaciLOK (Lumbar spine fixation system) and its implantation
instrumentation, is expected to complete and reach “design freeze” in the near future. The
development team and the inventor have been applied in ensuring that the FaciLOK can be
successfully and safely implanted into patients with a minimum level of surgical skill, thereby
broadening the scope for market adoption.

TruSpine Technologies Limited

101 Finsbury Pavement, Moorgate, London, EC2A 1RS
Tel: +44 (0)20 3638 5025 Company Number 09345973
The belief now is that we have the strong potential for adoption by organisations such as ambulatory
centres and pain management specialist, in addition to traditional hospitals.

The CerviFAS (Cervical spine fixation system) and its implementation are also very close to design
freeze, which means one can follow very close behind the other in the FDA approval process.
Assuming the availability of sufficient funding, then it would also be possible to run the two in
parallel.

HealthTech Summit Update

Last summer TruSpine were independently cited as one of the 20 most promising Med Tech
companies in Europe, and consequently were asked to present at the Healthtech Summit in
Lausanne.

From this experience it became further evident that TruSpine appear to be the only company
applying any level of true innovation to the spine market at this point, this was further confirmed by
other major med tech company representatives in attendance during the summit.

In addition, it became apparent that TruSpine is certainly on the radar of the major players in the
spine market, who appear to be keeping a watching brief to see how things develop.

As previously stated, the market is characterised by the acquisition of emerging companies by the
major players at an appropriate time in their development, particularly when there is disruptive
technology involved such as is the case with TruSpine.

The selection for this event certainly assisted in building TruSpine’s profile, as well as underpinning
the belief that the company’s strategy and products do have the scope and potential we all believe
they do.

New additions

Simon Stephens – Group CEO

The company is very pleased to confirm the recent appointment of Mr Simon Stephens as the
company’s Group CEO. Simon brings with him a wealth of experience in leveraging value from tech
businesses in general, as well as specialist expertise in Med Tech development, most recently in the
transcatheter mitral valve sector. Simon also has a strong contact base in the City.

TruSpine Technologies Limited

101 Finsbury Pavement, Moorgate, London, EC2A 1RS
Tel: +44 (0)20 3638 5025 Company Number 09345973
We believe that Simon is properly qualified and experienced to provide the cohesive strategy and
leadership, necessary not only to take the company through the final phase of completion and FDA
clearance of its products, but also to navigate a clear course through the forthcoming planned IPO.

Professor Abdallah Raweh – Medical Advisory Board

Professor Raweh is an internationally acclaimed Cardiac surgeon who operates out of London, New
York, Milan, Dubai and Abu Dhabi. Professor Raweh has received many accolades and enjoyed
numerous high profile positions during his career, including his current position as Vice Rector and
Full Professor of Cardiac Surgery, L.U. de S University, Lugano, Switzerland.

Professor Raweh brings with him a wealth of knowledge and medical expertise, particularly in the
areas of Cardio Thoracic and vascular surgery. He is also very well placed to assist in promoting
adoption of the company’s products in some key geographical areas.

IPO
Plans for Truspine to IPO in the coming months with Cenkos Securities of London and the rest of the
IPO team remain on track, and at a meeting last week it was agreed that the listing should be
secured as soon as possible this year. This is planned to be concurrent with FDA clearance for the
first product, which will cement a far more substantial pre-money valuation.

As previously stated an IPO will not only provide the company with enhanced corporate credibility,
but will also facilitate an opportunity to raise the next level of funding required for the wider
commercialisation of the company’s products. Assuming the company is not pursued for acquisition
in a trade sale first, which as has been stated before is characteristic of the spine market.

R&D Tax Credit claim

The company is progressing well with a multi hundred thousand GBP claim in association with
KPMG, who have now completed their initial DD and validity checks. This included a meeting with
the inventor in the last week of January, as well as several meetings with the company and their
financial advisers. It will take a further 2 weeks to confirm the exact quantum of the claim, at which
point KPMG will commence work on the submission itself.

KPMG expect that the process will take circa 2 months in total to complete. A bridge funding option
has already been arranged to enable the company to access part of the claim in advance to support
the FDA application process.

TruSpine Technologies Limited

101 Finsbury Pavement, Moorgate, London, EC2A 1RS
Tel: +44 (0)20 3638 5025 Company Number 09345973
This R&D Tax Credit claim will provide the company with a large part of the remaining vital funding
requirement to compete the first FDA clearance, following which the company will clearly be in a
very strong position.

Summary
We hope that the information above provides you with a more incisive view of the company’s
progress and current position. Should you wish to contact us to discuss any of the matters raised, or
to discuss investment opportunities into TruSpine in general, please contact the persons listed below
in the first instance.

Contact information

The Enduro Partnership

mike@enduropartnership.com or sarah@enduropartnership.com
Tel: +44 (0)1293 804780

TruSpine Technologies Limited

101 Finsbury Pavement, Moorgate, London, EC2A 1RS
Tel: +44 (0)20 3638 5025 Company Number 09345973