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Oxygenation and Hematology
Oxygenation and Hematology
Oxygenation and Hematology
Ultrasound Procedure:
Client’s blood is obtained by venipuncture
Definition:
“Sonography”, involves exposing part of the body to high The blood is mixed in a tube that contains sodium
frequency sound waves to produce pictures of the inside of citrate to prevent the clotting process from starting before
the body. the test.
Doppler Ultrasonography
The blood cells are separated from plasma.
Special ultrasound technique that evaluates blood velocity
as it flows through a blood vessel, including the body’s
major arteries & veins in abdomen, arms, legs, & neck. Patient’s blood plasma is added with a protein
thromboplastin that converts prothrombin to thrombin.
TYPES:
Color Doppler The mixture is kept in a warm water bath at 37C for
1-2 minutes.
Power Doppler
Calcium chloride is added to the mixture.
Spectral Doppler
The test is timed from the addition of calcium
Indication: chloride until the plasma clots.
Variety of conditions & to assess organ damage following
illness; limitations with bowel 0r organs obscured by the
bowel, large patients. Complications:
Mild dizziness and a possibility of a bruise or swelling
Materials & Equipment:
in the area where the blood was drawn.
Ultrasound scanner
Partial Thromboplastin Time
Examination table
Definition:
Clear water-based gel Partial thromboplastin time (PTT) is a blood test that
looks at how long it takes for blood to clot. It can help tell if
Loose- fitting clothing for exam gown. you have bleeding or clotting problems.
Indications:
Complications: The test may also be used to monitor patients who
No known complications. are taking heparin, a blood thinner.
Preparation:
Wear comfortable, loose- fitting clothing for your Preparation:
ultrasound exam. Medicines-If you are receiving heparin therapy, this
test may need to be repeated at regular intervals to
May be asked to wear a gown during the procedure. evaluate your response to treatment. The health care
provider may tell you to stop taking certain drugs
Other preparation depends on the type of examination before the test. Drugs that can affect the results of a PTT
the client will have. test include antihistamines, vitamin C (ascorbic acid),
aspirin, and chlorpromazine (Thorazine).
Hematoma (blood accumulating under the skin) COMPLETE BLOOD COUNT (CBC)
The complete blood count (CBC) is a common blood
Infection (a slight risk any time the skin is broken) test that evaluates the three major types of cells in the
blood: red blood cells, white blood cells, and platelets.
Multiple punctures to locate veins Why It's Done
A CBC may be ordered as part of a routine checkup, or if
PLATELET DETERMINATION your child is feeling more tired than usual, seems to have
an infection, or has unexplained bruising or bleeding.
Definition: • Red blood cells: The CBC's measurements of red
A platelet count is a test to measure how many platelets blood cell (RBC) count, hemoglobin (the oxygen-
you have in your blood. Platelets help the blood clot. They carrying protein in RBCs), and mean (red) cell volume
are smaller than red or white blood cells. (MCV) provides information about the RBCs, which carry
oxygen from the lungs to the rest of the body. These
measurements are usually done to test for anemia, a
Complications: common condition that occurs when the body has
Excessive bleeding insufficient red blood cells.
• White blood cells: The white blood cell (WBC) count
Fainting or feeling light-headed measures the number of WBCs (also called leukocytes)
in the blood. The WBC differential test measures the
Hematoma (blood accumulating under the skin) relative numbers of the different kinds of WBCs in the
blood. WBCs, which help the body fight infection, are
Infection (a slight risk any time the skin is broken) bigger than red blood cells and there are far fewer of
them in the bloodstream. An abnormal WBC count may
indicate an infection, inflammation, or other stress in
Multiple punctures to locate veins
the body. For example, a bacterial infection can cause
the WBC count to increase, or decrease, dramatically.
Materials and Equipment: • Platelets: The smallest blood cells, platelets play an
important role in blood clotting and the prevention of
Microscope
bleeding. When a blood vessel is damaged or cut,
platelets clump together and plug the hole until the
Improved Neubauer counting chamber blood clots. If the platelet count is too low, a person can
be in danger of bleeding in any part of the body.
RBC Pipette The CBC can also test for loss of blood, abnormalities in the
production or destruction of blood cells, acute and chronic
Platelet diluting fluid. It is prepared as follows infections, allergies, and problems with blood clotting.
Preparation
a) Procaine hydrochloride : 3.0 g
No special preparations are needed. Having your
child wear a short-sleeve shirt on the day of the test can
b) Sodium chloride : 10 g make things easier for the technician who will be drawing
blood.
c) Distilled water to : 100 ml
The Procedure
Filter it through Whatman No. 44 filter paper and Not much blood is drawn in a CBC. A health
store in a clean and dry plastic container. It is stable at 2- professional will usually draw the blood from a vein. For an
infant, the blood may be obtained by puncturing the heel
8°C.
with a small needle (lancet). If the blood is being drawn
from a vein, the skin surface is cleaned with antiseptic, and
an elastic band (tourniquet) is placed around the upper arm
Preparations and Procedure: to apply pressure and cause the veins to swell with blood. A
Mix the blood specimen carefully. needle is inserted into a vein (usually in the arm inside of
the elbow or on the back of the hand) and blood is
By using RBC pipette draw blood up to 0 5 mark. withdrawn and collected in a vial or syringe.
After the procedure, the elastic band is removed.
Wipe excess blood on the outside of the pipette. Once the blood has been collected, the needle is removed
and the area is covered with cotton or a bandage to stop
the bleeding. Collecting blood for this test will only take a
The diluting fluid is drawn up to mark 101 (blood is few minutes.
diluted 1:200)
What to Expect
Mix the contents in the bulb thoroughly. Either method (heel sticking or vein withdrawal) of
collecting a sample of blood is only temporarily
After 5 minutes, discard the first drop, then transfer uncomfortable and can feel like a quick pinprick. Afterward,
a small drop on one side of the counting chamber there may be some mild bruising, which should go away in
a few days.
Place the filled mounted counting chamber under a Getting the Results
petri dish with a moist filter paper. Let it stay undisturbed The blood sample will be processed by a machine.
for 15 minutes. (This permits the platelets to settle and also Parts of the CBC results can be available in minutes in an
pre vents evaporation of diluting fluid in the chamber).
emergency, but more commonly the full test results come • factors that may affect the ACT include hemodilution,
after a few hours or the next day. hypothermia, cardioplegic solutions, platelet
If a CBC test points to anemia, infection, or other concerns, dysfunction, hypofibrinogenemia, other coagulopathies
your child's doctor may repeat the test just to be sure. If the and certain drugs. ACT is prolonged in patients with
second set of test results come back the same, your doctor antiphospholipid antibodies and may not demonstrate a
will likely order further lab tests for your child to determine linear response to heparin. If unexpected test results
what's causing the problem and how to treat it. are obtained, more specific coagulation tests should be
performed for further investigation.
Risks • The APTT is preferred to the ACT for monitoring
The CBC test is considered a safe procedure. However, standard heparin therapy (for treatment of venous
as with many medical tests, there are some problems that thromboembolism, unstable angina, myocardial
can occur with having blood drawn: infarction etc.), because it shows significantly better
• fainting or feeling lightheaded precision and is less subject to technical variability. On
• hematoma (blood accumulating under the skin the other hand, the ACT is the recommended test for
causing a lump or a bruise) monitoring heparin in interventional cardiology
procedures.
• pain associated with multiple punctures to locate a
• The ACT is a test of whole blood that uses a strong
vein
contact activator of the intrinsic coagulation pathway,
either celite or kaolin. As a result, it is linearly
Helping Your Child
responsive to the high concentrations of heparin used
Having a blood test is relatively painless. Still,
during bypass (1-5 U/mL). The usual monitoring
many children are afraid of needles. Explaining the test in
protocol consists of a baseline ACT followed by a bolus
terms your child can understand might help ease some of
of heparin. The baseline ACT should be shorter than
the fear.
200 seconds and the postheparinization ACT should be
Allow your child to ask the technician any questions he or
longer than 450 seconds prior to the onset of bypass.
she might have. Tell your child to try to relax and stay still
during the procedure, as tensing muscles and moving can • During bypass, the ACT is repeated every 15 to 20
make it harder and more painful to draw blood. It also may minutes; if the result is less than 450 seconds,
help if your child looks away when the needle is being additional heparin is administered. The ACT is designed
inserted into the skin. to be prolonged about 100 seconds above baseline for
each unit per milliliter of heparin concentration in a
typical patient. At the completion of CPB, heparin is
BLEEDING TIME neutralized with protamine and the ACT is performed
Bleeding time is a blood test that looks at how fast again to ensure that it has returned to baseline levels.
small blood vessels close to stop you from bleeding.
Whole blood clotting time
How the Test is Perform 1. 5ml of blood is placed in a glass container, kept at
A blood pressure cuff inflates around your upper body temperature and observed
arm. While on the cuff is on your arm, the health care • A clot should occur in 5 to 15 minutes
provider makes two small cuts on the lower arm. They are Prolonged = Severe deficiency of any of the
just deep enough to cause a tiny amount of bleeding. coagulation proteins
The blood pressure cuff is immediately deflated. • The clot should retract in 30 to 60 minutes
Blotting paper is touched to the cuts every 30 seconds until Weak friable clot = hypofibrinogenaemia
the bleeding stops. The health care provider records the Early dissolution = enhanced fibrinolysis
time it takes for the cuts to stop bleeding.
TERMINOLOGIES RELATED TO HEMATOLOGY
How to Prepare for the Test Clot Retraction: The rate and degree of contraction of the
Certain medications may change the test results. blood clot.
Always tell your doctor what medications you are taking,
even over-the-counter drugs. Drugs that may increase
bleeding times include dextran, nonsteroidal anti- Coagulation Time: The time required for venous blood, in
inflammatory drugs (NSAIDs), and salicylates (including the absence of all tissue factors, to clot in glass tubes
aspirin). under controlled conditions.
Your doctor may tell you to stop taking certain
medicines a few days before the test. Never stop taking
medicine without first talking to your doctor. Color Index: The ratio between the amount of hemoglobin
and the number of red blood cells.
How the Test Will Feel
The tiny cuts are very shallow. Most people say it
feels like a skin scratch. Complete Blood Count: A hematology study which
consists of a red cell count, white cell count, hematocrit,
Why the Test is Perform hemoglobin, and blood smear study including differential
This test helps diagnose bleeding problems. white cell count.
Normal Results
Bleeding normally stops within 1 to 9 minutes. Color Index: The ratio between the amount of hemoglobin
However, values may vary from lab to lab. and the number of red blood cells.
Additional conditions under which the test may be Differential Count: An en1.meration of the types of white
performed: blood cells seen on a stained blood smear.
• Acquired platelet function defect
• Congenital platelet function defects Ecchymosis: Subcutaneous extravastion of blood covering
• Primary thrombocythemia a large area.
• Von Willebrand's disease
Hemostasis: The checking of the flow of blood, especially Severe burn victims.
from a vessel. In Vitro: Within a test tube (glass, etc.).
CONTRAINDICATION
In Vitro: Within a test tube (glass, etc.). previous malaria or hepatitis
In Vivo: Within the living organism, as in life. a history of intravenous drug abuse
Normocyte (Erythrocyte): A red blood cell of normal size. donors with high-risk sexual behaviour
(variably defined)
Plasma: The fluid portion of the blood composed of serum
and fibrinogen, obtained when an anticoagulant is used. donors who have previously been transfused
(12-month min. deferral)
Plasma Cell: A lymphocyte-like cell with an eccentrically
placed deep-staining nucleus. The nuclear chromatin is MATERIALS AND EQUIPMENTS
distributed in a "wheel-spoke" fashion. The cytoplasm is blood pack with SF 518
deep blue with a lighter halo about the nucleus.
thermometer
Platelet: Thrombocyte.
blood pressure cuff
IV cathetertape
Thrombocytopenia: A decrease in blood platelets; also
thrombopenia. alcohol and betadine prep pads
What to expect during echocardiography? What you may see and hear during
Echocardiography (echo) is painless and usually echocardiography?
takes less than an hour to do. For some types of echo, your As the doctor or sonographer moves the transducer
doctor will need to inject saline or a special dye into one of around, different views of your heart can be seen on the
your veins to make your heart show up more clearly on the screen of the echo machine. The structures of the heart will
test images. This special dye is different from the dye used appear as white objects, while any fluid or blood will appear
during angiography (a test used to examine the body's black on the screen.
blood vessels). Doppler ultrasound techniques often are used
For most types of echo, you'll be asked to remove during echo tests. Doppler ultrasound is a special
your clothing from the waist up. Women will be given a ultrasound that shows how blood is flowing through the
gown to wear during the test. You'll lay on your back or left blood vessels.
side on an exam table or stretcher. This test allows the sonographer to see blood
Soft, sticky patches called electrodes will be flowing at different speeds and in different directions. The
attached to your chest to allow an EKG(electrocardiogram) speeds and directions appear as different colors moving
to be done. An EKG is a test that records the heart's within the black and white images.
electrical activity. The human ear is unable to hear the sound waves
A doctor or sonographer (a person specially trained used in echo. If Doppler ultrasound is used, you may be
to do ultrasounds) will apply gel to your chest. The gel helps able to hear "whooshing" sounds. Your doctor can use these
the sound waves reach your heart. A wand-like device sounds to learn about blood flow through your heart.
called a transducer will then be moved around on your
chest. What to expect after echocardiography?
The transducer transmits ultrasound waves into You usually can go back to your normal activities
your chest. Echoes from the sound waves will be converted right after having echocardiography (echo).
into pictures of your heart on a computer screen. During the If you have a transesophageal echo (TEE), you may
test, the lights in the room will be dimmed so the computer be watched for a few hours at the doctor's office or hospital
screen is easier to see. after the test. Your throat might be sore for a few hours
The sonographer will make several recordings of after the test.
the pictures to show various locations in your heart. The You also may not be able to drive right after a TEE.
recordings will be put on a computer disc or videotape for Your doctor will let you know whether you need to arrange
the cardiologist (heart specialist) to review. for someone to take you home.
During the test, you may be asked to change
positions or hold your breath for a short time so that the What does it shows?
sonographer can get good pictures of your heart. Echocardiography (echo) shows the size, structure,
At times, the sonographer may apply a bit of and movement of the various parts of your heart. This
pressure to your chest with the transducer. This pressure includes the valves, the septum (the wall separating the
can be a little uncomfortable, but it helps get the best right and left heart chambers), and the walls of the heart
picture of your heart. You should let the sonographer know chambers. Doppler ultrasound shows the movement of
if you feel too uncomfortable. blood through the heart.
This process is similar for fetal echo. However, in Echo can be used to:
that test the transducer is placed over the pregnant • Diagnose heart problems
woman's belly at the location of the baby's heart.
• Guide or determine next steps for treatment
Transesophageal Echocardiography
Transesophageal echo (TEE) is used when your • Monitor changes and improvement
doctor needs a more detailed view of your heart. For • Determine the need for more tests
Echo can detect many heart problems. Some may
be minor and pose no risk to you. Others can be signs of
serious heart disease or other heart conditions. Your doctor
may use echo to learn about:
CARDIAC CATHETERIZATION
• The size of your heart. An enlarged heart can
be the result of high blood pressure, leaky Cardiac catheterization (heart cath) is the
heart valves, or heart failure. insertion of a catheter into a chamber or vessel of the heart.
• Heart muscles that are weak and aren't moving This is done for both investigational and interventional
(pumping) properly. Weakened areas of heart purposes. Coronary catheterization is a subset of this
muscle can be due to damage from a heart technique, involving the catheterization of the coronary
attack. Weakening also could mean that the arteries.
area isn't getting enough blood supply, which
may be due to coronary heart disease. Your doctor may perform cardiac catheterization to:
• Problems with your heart's valves. Echo can • Diagnose or evaluate coronary artery disease
show whether any of the valves of your heart
don't open normally or don't form a complete • Diagnose or evaluate congenital heart defects
seal when closed. • Diagnose or evaluate problems with the heart valves
• Problems with your heart's structure. Echo can • Diagnose causes of heart failure or cardiomyopathy
detect many structural problems, such as
a hole in the septum and other congenital Right Heart Catheterization
heart defects. Congenital heart defects are Right heart catheterization (also known as
structural problems present at birth. pulmonary artery catheterization or Swan-Ganz
• Blood clots or tumors. If you've had a stroke, catheterization) is a common procedure in critically ill
echo might be done to check for blood clots or patients. The catheter is a long thin hollow tube that is
tumors that may have caused it. placed through a central venous catheter and is then
guided through the chambers of the heart and into the large
Risks blood vessels of the lungs. The catheter is left in place in a
Transthoracic and fetal echocardiography (echo) pulmonary (lung) artery. This catheter measures pressures
have no risks. These tests are safe in adults, children, and in the heart and large blood vessels and checks how well
infants. the heart is working.
If you have a transesophageal echo (TEE), some Some common situations in which doctors recommend right
risks are associated with the medicine given to help you heart catheterization include:
relax. These include a bad reaction to the medicine, • Low blood pressure (hypotension or shock) -
problems breathing, or nausea (feeling sick to your When the blood pressure remains very low despite
stomach). giving fluids and medications to the patient.
Your throat also might be sore for a few hours after
the test. Rarely, the tube used during TEE can cause minor • Kidney abnormalities - When urine flow is too low
throat injuries. to get rid of the wastes of the body and giving fluids
Stress echo has some risks, but they're related to and/or diuretics (medicines intended to stimulate
the exercise or medicine used to raise your heart rate, not urine output) does not increase urine output.
to the echo. Serious complications from stress tests are • Lung water (pulmonary edema) - In patients with
very uncommon. Go to the Diseases and Conditions a lot of water in their lungs due to heart failure or
Index Stress Testing article for more information about the inflammation of the lungs, the catheter can help
risks of that test. monitor treatments to prevent more water from
accumulating in the lungs.
Key Points
• Echocardiography (echo) is a painless test that • Specific heart abnormalities - There are some
uses sound waves to create pictures of your heart. abnormalities of the heart - such as when fluid
collects around the heart or a heart valve doesn't
• This test gives your doctor information about the close properly - in which measurements with the
size and shape of your heart and how well your heart's catheter help to make the diagnosis and guide
chambers and valves are working. In addition, a type of treatments.
echo called Doppler ultrasound shows how well blood flows
through the chambers and valves of your heart. Left heart catheterization
• Your doctor may recommend echo if you have signs A test that permits your doctor to inspect the inside
and symptoms of heart problems. The test can be used to of your heart's left chambers, where blood is pumped out to
confirm a diagnosis, determine the status of an existing the rest of the body. The procedure is also called coronary
problem, or help guide treatment. arteriography (ar-TEER-ee-og-ruh-fee) or a "left heart cath."
• There are several types of echo. Transthoracic and Retrograde Approach
stress echo are standard types of the test. Transesophageal Catheter maybe introduced percutaneously by
echo (TEE) is used if the standard tests don't produce clear puncture of the femoral artery or by direct brachial
results. A fetal echo is used to look at an unborn baby's approach and advanced under fluoroscopic control into the
heart. A three-dimensional (3D) echo may be used to help aorta and into the left ventricle.
diagnose heart problems in children or plan and Transseptal approach
monitor heart valve surgery. Catheter is passed from the right femoral vein into
• Echo is done in a doctor's office or hospital. The the right atrium. A long needle is passed up through the
test usually takes up to an hour to do. A standard echo catheter and is used to puncture the septum of the right
doesn't require any special preparations or followup. If and left atria
you're having a TEE, you usually shouldn't eat or drink for 8
hours prior to the test. Indications & Contraindications:
Some of the indications for cardiac catheterization
• During a standard echo, your doctor or procedure are -
sonographer will move a wand-like device called a
• Unstable angina or Chest pain [uncontrolled
transducer around on your chest to get pictures of your
with medications or after a heart attack]
heart. During a TEE, the transducer will be put down your
throat to get a better view of your heart. • Heart attack
• Before a bypass surgery
• A cardiologist (heart specialist) will review the
• Abnormal treadmill test results
results from your echo.
• Determine the extent of coronary artery
• You usually can go back to your normal activities disease
right after having echo. If you have TEE, you may be
• Disease of the heart valve causing symtpoms
watched for a few hours at the doctor's office or hospital
(syncope, shortness of breath)
after the test.
• To monitor rejection in heart transplant
• Transthoracic and fetal echo have no risks. If you patients
have TEE, some risks are associated with the medicine • Syncope or loss of consiousness in patients
given to help you relax. Rarely, the tube used in TEE can with aortic valve disease
cause minor throat injuries. The risks for stress echo are
related to the exercise or medicine used to raise your heart Some of the relative contraindiciations for
rate. Serious complications from stress echo are rare. cardiac catheterization are
• Allergy to contrast (dye) medium
• Uncontrolled Blood Pressure (Hypertension) Procedure
• Problems with blood coagulation • In the catheterization laboratory, the insertion area
(Coagulopathy) (usually the groin, neck, or forearm) is cleansed with a
• Kidney failure or dysfunction sterilizing solution, shaved, and covered with sterile
• Severe anemia drapes. A small-needle injection of a local anesthetic is
• Electrolyte imbalance used to numb the area.
• Fever • A small incision is made and a pencil-sized plastic tube,
• Active systemic infection called a sheath, is inserted into the artery (e.g., femoral
• Uncontrolled rhythm disturbances artery, carotid artery) or vein. A catheter, which is
(arrhythmias) usually 2 to 3 mm in diameter, is passed via the sheath
• Uncompensated heart failure through the artery to the heart, and into a coronary
• Transient Ischemic attack artery.
• A contrast agent (dye) is injected into the catheter to
Preparations: show areas of blockage and angiograms of the artery
• Patients may be required to be admitted to the hospital are taken. The dye often causes a "hot-flash" sensation
the night before the procedure. For some patients, throughout the body that lasts for 10 to 15 seconds.
overnight stay is not required. • In some cases, a catheter is passed through the sheath
to the heart's left ventricle and dye injected to show
• Nilper oral [NPO] or nothing to eat or drink by mouth how the left ventricle is functioning.
6-8 hours before the test.
• The cardiologist will explain the procedure and risks
Postprocedure
associated with it.
• Consent form should be signed before the procedure. 1. record blood pressure measurement and apical
pulse every 15 minutes (or more frequently) until vital
• Any questions or doubts should be asked and clarified signs are stable to discern dysrrhytmias
with the doctor before surgery.
2. Check peripheral pulses in affected extremity;
• The doctor should be informed of allergies to evaluate extremity temperature, color, and complaints
medications, iodine or food. It should also be of pains, numbness or tingling sensation to determine
documented legibly in the patient’s chart. signs of arterial insufficiency.
• Previous allergic reactions to contrast dyes must be
mentioned.
3. Watch cutdown sites for hematoma formation.
Question patient about increase in pain or tenderness
• Catheterization
procedure requires X-ray fluoroscopy. at site.
Women patients in childbearing age can undergo 4. Assess for complaints of chest pain and report
pregnancy test to rule out pregnancy.
immediately. MI (Myocardial Infarction) may occur and
• Medications that are taken on the day of cardiac is serious complications of cardiac catheterization.
catheterization should be discussed with the doctor. 5. Enforce activity restrictions which are based on
Some medicines taken for blood thinning (e.g., coagulation status and whether avascular closure
Aspirin), erectile dysfunction (Sildenafil or Tadalafil) or method was employed. (2-24 hours)
diabetic medication (metformin) needs to be stopped
on the day or few days before the procedure. 6. Evaluate complaints of back, thigh, or groin pain
(may indicate) retroperitoneal bleeding.
• Kidney disease should be assessed before, as
contrast materials or dyes may not be used in patients 7. Be alert of signs and symptoms of vagal reaction
with abnormal kidney function. (nausea, diaphoresis, hypotension, bradycardia); treat
• Some blood tests and electrocardiogram (ECG) will be as directed with atropine and fluids.
performed before the procedure.
Complications:
• A mild sedative will be given orally or intravenously to The overall risk for complications from cardiac
comfort the patient and relieve anxiety. catheterization is about 1 in 1000. Contrast dyes cause
• Allpersonal belongings and jewellery will be removed adverse effects in almost 1 out of 10 patients. The
and patient will be dressed in a hospital gown before common side effect is nausea or vomiting. Some of the
being transported to the catheterization laboratory. complications due to dye allergy are
• Fast heartbeat
• Slow heartbeat
Nursing patient Care considerations:
• Nausea
Preprocedure:
• Vomiting
• Client should have X-ray, CBC with differential, • Shock
urinalysis, and 12 lead ECG. • Kidney failure
• Know which approach which to be used in order to • Epilepsy
anticipate possible complications. • Itching
• Rashes
• Withhold food and fluid 6 hours before procedure. Few other complications are
• Ascertain history of previous allergies. • Bleeding at the insertion site
• Mark distal pulses for easy reference after • Damage to the blood vessels used for catheter entry
catheterization. • Infection
• Ventricular arrhythmias
• Explain to patient that he would lying on examination
• Pneumothorax [air collection between the chest wall
table for a prolong period that he may experience
and the lungs]
certain sensations.
• Cardiac tamponade [fluid collection around the heart]
o Occasional thudding sensation in the chest. • Heart attack
o Strong desire to cough may occur during contrast • Stroke [0.1%]
medium injection. • Air embolism
o Transient feeling of hot flushes or nausea as the • Death [0.1- 0.2%]
contrast medium is injected.
CENRAL VENOUS PRESSURE
• Evaluate client’s emotional status before Indications
catheterization.
• Inability to achieve adequate peripheral venous
o Is this patient’s first catheterization? access
o Is patient apprehensive about procedure? • Delivery of substances not safely given via
o Ask whether has heard stories about having a peripheral IV (TPN, vasopressors, etc.)
catheterization. • Hemodialysis, CVVH, plasmapheresis
• Dentures, glasses or hearing aids should be sent with • Measurement of cardiac filling pressures
patient for procedure. • Placement of pulmonary artery catheter
• Have patient void before procedure. • Placement of transvenous pacer
• Access for frequent blood sampling H. Hemothorax
• Remember that triple lumen catheters are less • Seen most commonly with arterial puncture
useful than large bore IV’s for rapid volume administration – • Suspect with development of post procedure
unless introducer catheter placed. effusion/drop in hematocrit
I. Hydrothorax
Contraindications J. Hemomediastinum
• Absolute: K. Hydromediastinum
o Operator inexperience L. Infection (insertion site, thrombophlebitis, bacteremia,
sepsis, cellulitis, osteomyelitis)
o Uncooperative/combative patients
o Uncorrected coagulopathy in a stable • Minimize risk with wide sterile barrier precautions –
drape should cover head, and extend past waist
patient
• Relative:
• Hand washing
o Uncorrected coagulopathy in an unstable • Physician should not have artificial/long nails
patient • Chlorhexidine instead of iodine – good scrub (friction
o Cellulitis over anticipated insertion site for at least 30 seconds), at least 10cm in diameter
o Injury or previous surgery to SVC (prior spanning from ear to clavicle to trachea. Allow to dry
XRT, prior long term venous cannulation at site. completely.
o Inability to tolerate pneumothorax (femoral • Chlorhexidine disc: Use of a chlorhexidine-impregnated
vein should be considered) disc (e.g. Biopatch) around the catheter insertion site
o Ability to provide adequate care via has been shown to reduce the rate of catheter-related-
BSI. When placing these discs, make sure that the
peripheral access
catheter is fed through the hole in the disc and that the
o Morbid obesity. Consider placement of line
chlorhexidine side of the disc faces the skin (white side
in cephalic vein on upper outer chest using ultrasound facing skin, light blue side facing up).
guidance beyond the rib edges.
o Vasculitis • Risk of infection increases with each needle stick. If you
are having trouble, seek help!
o COPD/bullous lung disease (subclavian
lines) • If your patient requires removal of hair prior to the
procedure, remember that razors can cause significant
o Congenital heart disease (Glenn or Fontan
skin abrasions – clipping is recommended.
anastamoses). These patients have increased risk of
clotting with upper body central lines. Consider a femoral • Appropriately anchor/sew catheter in place to prevent it
approach. from moving in and out of the skin.
o Presence of a pacemaker or ICD – • Minimal number of ports and minimal accessing is
especially relevant for subclavian lines, pulmonary artery associated with decreased infection rate.
catheters, and right IJ lines. The more recently placed the • Catheter related bacteremia rates:
device, the more likely lead dislodgement becomes. o 8.6% with IJ vs. 3.9% for subclavian in
Consider having devices interrogated following study by Ruesche et al, 2002 but this was not
placement/removal of CVC’s. statistically significant.
M. Injury to adjacent nerves
Risks and Complications • Brachial plexus injury has been reported with IJ catheter
Complication Internal Subclavian Femoral insertions
Jugular • Femoral nerve injury has been reported with femoral
Arterial 6.3-9.4% 3.1-4.9% 9.0-15.0% catheter placements
puncture N. Malposition of catheter tip:
Hematoma <0.1-2.2% 1.2-2.1% 3.8-4.4% • Reported in 1.8 – 14% of IJ placements (Ruesch et al
Hemothorax N/A 0.4-0.6% N/A 2002, Gladwin et al 1999, Iovino et al 2001)
Pneumothorax <0.1-0.2% 1.5-3.1% N/A • Reported in 1.8-9.3% of Subclavian placements
Total 6.3-11.8% 6.2-10.7% 12.8-19.4% (Ruesch, Mansfield, Iovino)
O. Pneumothorax:
(McGee and Gould, NEJM 2003 – without U/S guidance):
• Increased rate of pneumothorax with multiple passes of
needle. If having trouble, ask for help from experienced
A. Air embolization
person.
• Venous (pulmonary) > arterial (via septal defect or
AVM)
• Patient may cough, develop pleuritic pain, develop
cardiopulmonary compromise, or be asymptomatic
• 50-100 mL of entrained air can be fatal via “air lock” or
obstruction of the pulmonary outflow tracts.
• Remember to check a chest x-ray whether or not a line
was successfully placed after attempting IJ or
• Higher risk in patients spontaneously breathing with subclavian line placement
large negative intrathoracic pressures, low CVP.
• If air aspirated, make sure to check a delayed chest x-
• Minimize risk by placing patients in Trendelenberg, ray as sometimes pneumothoraces are not immediately
quick insertion of guidewire through needle, asking visible
patient to valsalva, clamping all but proximal (brown) P. Subcutaneous fluid infiltration
ports during insertion, hum/exhalation with removal of
central lines.
• Important to confirm that all ports draw back blood and
flush easily.
B. Arrhythmia
• Usually associated with malpositioned catheter tip • Important to confirm location of line with post
procedure chest x-ray.
within right atrium or ventricle and resolves with pulling
Q. Tamponade (Cardiac)
back of guidewire or catheter.
• If unstable arrhythmia, proceed with ACLS algorithm • Ensure appropriate placement of catheter tip via chest
x-ray following procedure.
C. Arteriovenous fistula formation
R. Tracheal perforation/Endotracheal cuff perforation
• Most commonly seen when vein is reached through S. Vein thrombosis
punctured artery creating track.
D. Central Vein perforation
• Femoral veins: ~ 20% with thrombotic complications
(Mian et al 1997 & Merrer et al 2001)
• Ensure appropriate placement of catheter tip via chest
x-ray following procedure
• Internal Jugular: wide range of published thrombosis
rates (0-66%), but thought generally to be of lower risk
E. Clot embolization
for thrombosis than femoral lines.
F. Chylothorax
• Due to injury of thoracic duct • Subclavian: 1-2% risk of thrombosis; keep in mind that
there is about a 50% risk of subclavian stenosis
• Right IJ preferred side to avoid such injury development in patients undergoing subclavian line
G. Guidewire embolization placement for dialysis so don’t put dialysis catheters
• Keep your eye on the wire! there.
• Make sure that the guidewire is exiting the proximal • Thrombosis is most often due to poor tip placement.
(brown) port BEFORE threading the catheter through Ideally, the catheter tip should be in the lower 1/3 of
the skin. the SVC or at the caval-atrial junction, at which time the
• When possible, keep a hold on the guidewire.
tip is parallel to the vena cava walls. Tips that impinge artery at the wrist, but sometimes the femoral artery in the
against the vessel wall initiate venous thrombosis. groin or other sites are used. The blood can also be drawn
• Mural/catheter related thromboses are associated with from an arterial catheter. An arterial blood gas (ABG) test
increased risk of catheter-related infections. measures the acidity (pH) and the levels of oxygen and
carbon dioxide in the blood from an artery. This test is used
to check how well your lungs are able to move oxygen into
Management of Complications the blood and remove carbon dioxide from the blood.
Air Embolus:
• Suspect this if a patient decompensates during your Equipment:
procedure. • ABG kit
• Occlude any open lumen. • Ice
• Place patient in left lateral decubitus position &
Trendelenberg to position the RV outflow tract inferior Indications:
to the RV, thus floating air away from the outflow tract An ABG measures:
(Duran’ts position). • Partial pressure of oxygen (PaO2).
• Provide high FiO2 to encourage nitrogen resorption • Partial pressure of carbon dioxide (PaCO2).
• Attempt to aspirate air through your catheter. • pH.
• CXR in left lat decubitus may show air in heart & heart • Bicarbonate (HCO3)
exam may reveal mill wheel murmur
Arrhythmia: • Oxygen content (O2CT) and oxygen saturation (O2Sat)
values.
• Usually results from deep placement of the guidewire or
line and resolves upon repositioning. Contraindications:
• If unstable, initiate ACLS. • Cellulites or other infections over the radial artery.
Arterial Puncture: • Absence of palpable radial artery pulse.
• With needle only: withdraw needle and apply 5-10 • Negative results of an Allen test (collateral circulation
minutes of pressure. If patient develops bradycardia test), indicating that only one artery supplies the hand
(carotid massage), release pressure. and suggest to select another extremity as the site for
o CXR to r/o hemothorax arterial puncture.
o Frequent vitals • Coagulopathies or medium-to-high-dose anticoagulation
o Hematocrit checks therapy (eg, heparin or coumadin, streptokinase, and
• With dilator/catheter: Surgical emergency. Leave tissue plasminogen activator but not necessarily
line/dilator in place and call vascular surgery right aspirin) may be a relative contraindication for arterial
away. puncture.
Catheter Infection • History of arterial spasms following previous punctures.
• If catheter is no longer needed, remove catheter • Severe peripheral vascular disease.
• If blood cultures are positive, remove catheter • Abnormal or infectious skin processes at or near the
puncture sites.
• See separate Duke CVC Curriculum Website • Arterial grafts.
(DICON) for more detailed discussion
• Arterial puncture should not be performed through a
Catheter Knotting:
lesion or through or distal to a surgical shunt (eg, as in
• Leave catheter in place and request help from IR or a dialysis patient). If there is evidence of infection or
vascular service. peripheral vascular disease involving the selected limb,
Dysrhythmias: an alternate site should be selected.
• Usually occurs secondary to stimulation of myocardium
by catheter or guidewire Preparation:
• Usually resolves after withdrawal of catheter or • Tell your doctor if you:
guidewire o Have had bleeding problems or take blood thinners,
• If necessary, initiate ACLS protocols. such as aspirin or warfarin (Coumadin).
o Are taking any medicines.
• Try to estimate distance from insertion site to SVC prior
to insertion. o Are allergic to any medicines, such as those used to
Guidewire Embolization: numb the skin (anesthetics).
• Watch for arrhythmias and be prepared to manage • If you are on oxygen therapy, the oxygen may be
them. turned off for 20 minutes before the blood test. This is
called a "room air" test. If you cannot breathe without
• Obtain a CXR to check the location. the oxygen, the oxygen will not be turned off.
• Consult IR emergently for immediate removal. • Talk to your doctor about any concerns you have
Neck Hematoma: regarding the need for the test, its risks, how it will be
• Monitor patient for airway compromise/carotid done, or what the results may mean.
occlusion
Pneumothorax: Procedure:
• Monitor with serial chest x-rays if small and patient • A sample of blood from an artery is usually taken from
spontaneously breathing without respiratory distress. the inside of the wrist (radial artery), but it can also be
• If hemodynamic instability, place 14-16 gauge collected from an artery in the groin (femoral artery) or
angiocath in the 2nd intercostal space, midclavicular on the inside of the arm above the elbow crease
line. Remove needle, leave open to air, call for (brachial artery).
emergent chest tube placement. • You will be seated with your arm extended and your
wrist resting on a small pillow. The health professional
• If hemodynamically stable, not on positive pressure drawing the blood may rotate your hand back and forth
ventilation, and < 20%, then can observe with oxygen
and feel for a pulse in your wrist.
administration and serial chest x-rays
• If patient on positive pressure ventilation, even small • To prevent the possibility of damaging the artery of the
pneumothorax may require chest tube placement. wrist when the blood sample is taken, a procedure
Venous Thrombosis: called the Allen test may be done to ensure that blood
flow to your hand is normal. An arterial blood gas (ABG)
• If catheter is no longer needed, remove it test will not be done on an arm used for dialysis or if
• Anticoagulation with heparin/warfarin is indicated there is an infection or inflammation in the area of the
• Prevent this complication with appropriate tip puncture site.
placement. Make sure the tip does not impinge agains • The health professional taking a sample of your blood
the vessel wall. will:
o Clean the needle site with alcohol. You may be
ARTERIAL BLOOD GAS (ABG) given an injection of local anesthetic to numb that
area.
Definition: o Put the needle into the artery. More than one
An arterial blood gas (ABG) is a blood test that is performed needle stick may be needed.
using blood from an artery. It involves puncturing an artery
with a thin needle and syringe and drawing a small volume
of blood. The most common puncture site is the radial
o Allow the blood to fill the syringe. Be sure to morning of surgery. The chest and the area from
breathe normally while your blood is being where the graft will be taken are shaved.
collected. • Coronary angiography will have been previously
o Put a gauze pad or cotton ball over the needle site performed to show the surgeon where the arteries
as the needle is removed. are blocked and where the grafts might best be
o Put a bandage over the puncture site and apply positioned. Heart monitoring is initiated. The
firm pressure for 5 to 10 minutes (possibly longer if patient is given general anesthesia before the
you take blood-thinning medicine or have bleeding procedure.
problems).
Procedure
Complications
There is little chance of a problem from having blood • The patient is brought to the operating room and
sample taken from an artery. moved on to the operating table.
You may get a small bruise at the site. You can lower • An anesthetist places a variety of intravenous lines and
the chance of bruising by keeping pressure on the site injects an induction agent to render the patient
for at least 10 minutes after the needle is removed unconscious.
(longer if you have bleeding problems or take blood
thinners).
• An endotracheal tube is inserted and secured by the
anesthetist or assistant.
• You may feel lightheaded, faint, dizzy, or nauseated
while the blood is being drawn from your artery. • The chest is opened via a median sternotomy and the
• Ongoing bleeding can be a problem for people with heart is examined by the surgeon.
bleeding disorders. Aspirin, warfarin (Coumadin), and • The bypass grafts are harvested - frequent conduits
other blood-thinning medicines can make bleeding are the internal thoracic arteries, radial arteries and
more likely. If you have bleeding or clotting problems, saphenous veins. When harvesting is done, the patient
or if you take blood-thinning medicine, tell your doctor is given heparin to prevent the blood from clotting.
before your blood sample is taken.
• On rare occasions, the needle may damage a nerve or • In the case of "off-pump" surgery, the surgeon places
the artery, causing the artery to become blocked. devices to stabilize the heart.
• Though problems are rare, be careful with the arm or • If the case is "on-pump", the surgeon sutures cannulae
leg that had the blood draw. Do not lift or carry objects into the heart and instructs the perfusionist to start
for about 24 hours after you have had blood drawn cardiopulmonary bypass (CPB). Once CPB is
from an artery. established, the surgeon places the aortic cross-clamp
across the aorta and instructs the perfusionist to deliver
HEART BYPASS SURGERY cardioplegia to stop the heart.
DEFINITION FVC
Pulse oximetry is a non-invasive method allowing the
monitoring of the oxygenation of a patient's hemoglobin.
INDICATION
• Whenever a patient's oxygenation is unstable, including
intensive care, critical care, and emergency department
areas of a hospital. 80% to 120%
• The need to monitor the adequacy of arterial
oxyhemoglobin saturation Absolute FEV1/FVC ratio
CONTRAINDICATION
• The presence of an ongoing need for measurement of
pH, PaCO2, total hemoglobin, and abnormal
hemoglobins may be a relative contraindication to pulse Within 5% of the predicted ratio
oximetry.
TLC
EQUIPMENTS
• Pulse oximeter
PROCEDURE
• Plug the pulse oximeter in to an electrical socket, if
available, to recharge the batteries.
80% to 120%
• Turn the pulse oximeter on and wait for it to go through
Pulmonary function test Normal value (95
its calibration and check tests.
percent confidence
• Select the probe you require with particular attention to
interval)
correct sizing and where it is going to go. The digit
FEV1 80% to 120%
should be clean (remove nail varnish).
FVC 80% to 120%
• Position the probe on the chosen digit, avoiding excess Absolute FEV1/FVC ratio Within 5% of the
force. predicted ratio
• Allow several seconds for the pulse oximeter to detect TLC 80% to 120%
the pulse and calculate the oxygen saturation. FRC 75% to 120%
• Read off the displayed oxygen saturation and pulse RV 75% to 120%
rate.
Spirometry is considered a safe procedure with little risk.
FRC Because the test requires patients to breathe quickly and
deeply, some experience temporary shortness of breath or
lightheadedness. This test shouldn't be performed on
patients who have chest pain, a recent history of eye or
abdominal surgery, or serious heart disease.
DEFINITION: THORACOTOMY
Bronchoscopy is a technique of visualizing the inside of the
airways for diagnostic and therapeutic purposes. An DEFINITION:
instrument (bronchoscope) is inserted into the airways,
usually through the nose or mouth, or occasionally through
a tracheostomy
INDICATION
Diagnostic
• To view abnormalities of the airway
• To obtain tissue specimens of the lung in a variety of
disorders
•
To evaluate a person who has bleeding in the lungs,
possible lung cancer, a chronic cough, or a collapsed
lung
Therapeutic
• To remove secretions, blood, or foreign objects Thoracotomy is an incision into the pleural space of the
lodged in the airway chest.[1] It is performed by a surgeon, and, rarely, by
• Laser resection of tumors or benign tracheal and emergency physicians, to gain access to the thoracic
bronchial strictures organs, most commonly the heart, the lungs, the esophagus
• Stent insertion to palliate extrinsic compression of the or thoracic aorta, or for access to the anterior spine such as
tracheobronchial lumen from either malignant or is necessary for access to tumors in the spine.
benign disease processes
• Bronchoscopy is also employed in percutaneous INDICATION:
tracheostomy A physician gains access to the chest cavity (called the
thorax) by cutting through the chest wall. Reasons for the
• Surgical procedures on the airways, such as tracheal
entry are varied. Thoracotomy allows for study of the
reconstruction, often require the use of bronchoscopy
condition of the lungs; removal of a lung or part of a lung;
removal of a rib; and examination, treatment, or removal of
CONTRAINDICATION
any organs in the chest cavity
• Uncooperative Patient
• Acute Myocardial Infarction Contraindications:
Contraindications are those general to surgery and include
• Tracheal Stenosis coagulopathy that cannot be corrected, acute cardiac
• Asthma ischemia, and instability or insufficiency of major organ
systems. vascular structures, a separate laparotomy is
PREPARATION: recommended after the thoracotomy h as been completed.
• You will be asked to sign a consent form before a
bronchoscopy. Diagnosis/Preparation
Patients are told not to eat after midnight the night before
• Before you have a bronchoscopy, tell your doctor if you:
surgery. The advice is important because vomiting during
• Are taking any medicines.
surgery can cause serious complications or death. For
• Are allergic to any medicines, including anesthetics. surgery in which a general anesthetic is used, the gag reflex
• Have had bleeding problems or take blood-thinners, is often lost for several hours or longer, making it much
such as aspirin, clopidogrel (Plavix), or warfarin more likely that food will enter the lungs if vomiting occurs.
(Coumadin). Patients must tell their physicians about all known allergies
• Are or might be pregnant. so that the safest anesthetics can be selected. Older
• Your doctor may order other tests before your patients must be evaluated for heart ailments before
surgery because of the additional strain on that organ.
bronchoscopy, such as a complete blood count (CBC),
bleeding factors, arterial blood gas (ABG), or lung
function tests. Procedure:
• Do not eat or drink for at least 8 to 10 hours before the Three basic approaches are used.
procedure. • Limited anterior or lateral thoracotomy: A 6- to 8-cm
• Arrange to have someone drive you home after the intercostal incision is made to approach the anterior
procedure. structures.
• Posterolateral thoracotomy: The posterolateral
Procedure: approach gives access to pleurae, hilum,
The patient will often be given antianxiety and antisecretory mediastinum, and the entire lung.
medications (to prevent oral secretions from obstructing the • Sternal splitting incision (median sternotomy): When
view), generally atropine, and sometimes an analgesic such access to both lungs is desired, as in lung volume
as morphine. The patient is monitored during the reduction surgery, a sternal splitting incision is used.
procedure with periodic blood pressure checks, continuous Patients undergoing limited thoracotomy require a chest
ECG monitoring of the heart, and pulse oximetry. tube for 1 to 2 days and in many cases can leave the
A flexible bronchoscope is inserted with the patient in a hospital in 3 to 4 days. The principal indications for
sitting or supine position. Once the bronchoscope is thoracotomy are lobectomy and pneumonectomy (eg, lung
inserted into the upper airway, the vocal cords are cancer surgery). Video-assisted thoracoscopic surgery has
inspected. The instrument is advanced to the trachea and replaced thoracotomy for open pleural and lung biopsies.
further down into the bronchial system and each area is
inspected as the bronchoscope passes. If an abnormality is Complications:
discovered, it may be sampled, using a brush, a needle, or In addition to pneumothorax, complications from
forceps. Specimen of lung tissue (transbronchial biopsy) thoracotomy include air leaks, infection, bleeding and
may be sampled using a real-time x-ray (fluoroscopy). respiratory failure. Postoperative pain is universal and
Flexible bronchoscopy can also be performed on intubated intense, generally requiring opioids, and does interfere with
patients, such as patients in intensive care. In this case, the the recovery of respiratory function.
instrument is inserted through an adapter connected to the Hemorrhage, infection, pneumothorax, bronchopleural
tracheal tube. fistula, and reactions to anesthetics are the greatest
hazards.
Complications and Risks:
SPUTUM COLLECTION • Bullous disease, e.g. emphysema.
• Small volume of fluid (less than 1 cm
DEFINITION: • thickness on a lateral decubitus film).
Sputum specimen collection is a procedure designed to
collect expectorated secretions from a patient respiratory MATERIALS:
tract.
• 1.1% or 2% lidocaine with epinephrine for
PREPARATION
• local anesthesia
If there is any difficulty in expectorating, the physician may
• 3 ml syringe with 1 1/2” 25-gauge needle for
suggest the use of an inhalation, an expectorant, or
physiotherapy to aid in producing sputum for collection. The • anesthetic infiltration
sputum should be transferred to the laboratory within two • 3. 3. 1 1/2 “ 18-gauge needle
hours for analysis. • Skin prep solution, sterile drapes
• 2- 1-litre evacuated bottles for fluid collection
INDICATION: • Thoracentesis or blood set tubing (these are short IV
Sputum induction is indicated on patients with suspect tubings with a midpoint clamp fastened needle at one
tuberculosis who are unable to cough and produce an end, and a port for a second needle at the other end)
adequate sputum sample. o NOTE: A secondary IV tubing set may also be used
• Occlusive dressing
CONTRAINDICATION: • Universal precautions materials
Hypertonic saline will provoke cough in some patients. It is
“harsh” on the airways and may trigger severe PREPARATION:
bronchospasm. It will not be used on patients with known Patients should check with their doctor about continuing or
airway hypersensitivity such as asthma or on patients discontinuing the use of any medications (including over-
actively wheezing at the time of the request. Patients who the-counter drugs and herbal remedies). Unless otherwise
experience severe bronchospasm after a sputum induction instructed, patients should not eat or drink milk or alcohol
may be candidates for bronchodilator or aerosol therapy to for at least four hours before the procedure, but may drink
relieve induced bronchospasm (0.5 ml albuterol in clear fluids like water, pulp-free fruit juice, or tea until one
treatment cup). hour before. Patients should not smoke for at least 24 hours
prior to thoracentesis. To avoid injury to the lung, patients
EQUIPMENTS NEEDED: should not cough, breathe deeply, or move during this
• Sterile specimen container with cover procedure.
• Clean disposable gloves
• Facial tissues PROCEDURE:
• Emesis basin (optional)
• Toothbrush (optional) To change collection bottle:
• Completed identification labels
• Completed laboratory requisition (date, time, name of • Close clamp on collection tubing. Leave intercostal
tests, source of culture) needle in place. Remove needle from the full collection
• Small plastic bag for delivery of specimen to lab (or a bottle, and replace it into the new empty collection
container as specified by agency) bottle. Then, re-open clamp.
EQUIPMENTS
• Safety glasses
• Loose-fitting thermal insulated or leather gloves
• Long sleeve shirts and trousers without cuffs.
• In addition, safety shoes are recommended for people
involved in the handling of containers.
Advantages
• Minimal maintenance needed.
• Does not need to be refilled.
• Provides an unlimited oxygen supply (as long as it is
plugged in and turned on).
• Can be moved easily from room to room.
Disadvantages
• Requires electricity and will increase your electric bill,
especially if used 24 hours a day.
• Is affected by power surges and outages, requiring
backup oxygen system.