Prathamesh V.

Kolekar
Dept. Instrumentation Engg.
Vishwakarma Institute of Technology,
Pune.
 INTRODUCTION
 NANOSENSOR TECHNOLOGY
 TYPES
 APPLICATIONS
 FUTURE CHALLENGES
WHAT IS NANO SENSOR ?

NANO+SENSOR

SENSOR TRANSDUCER DETECTOR

•SENSES •CONVERTS •DETECTS

ACTION I/P TO CHANGE
ELECTRIC OCCURED
SIGNAL
 Sensors operating on the scale of atoms
and molecules
 Smaller size, lower weight, modest power
requirements
 Data storage systems
 PHYSICAL SENSORS
 CHEMICAL SENSORS
 BIOSENSORS

i. Bio receptors
ii. Transducers
iii. Detectors
 CANTILEVER ARRAY SENSORS
 NANOTUBE SENSORS
 NANOWIRE SENSORS
 CANTILEVER ARRAY SENSOR
 WORKING

BIO MICRO ELECRO

CHEMICAL/PHYSIC MECHANICAL
AL PROCESS SYSTEM
 PRECISSION CANTILEVERS: 300 nm THICKNESS TOLERANCE

 PRECISSION RESONANCE FREQUENCY: SPECIAL CANTILEVER

MOUNT

 EASY HANDLING: VERTICAL CHIP SIDEWALLS, OPTIONAL NON

STICKING

 CONTAMINATION FREE STORAGE

 SIZE / SHAPE
RECTANGULAR SHAPED SILICON BARS

DUOSENSIS SENSORS (2 CANTILEVERS PER CHIP)

OCTOSENSIS SENSORS (8 CANTILEVERS PER CHIP)

 FOR DIAGNOSIS OF DIABETES MELLITUS

Small amounts of acetone in a patient’s breath can be detected by cantilever

array sensor technique which may attribute to early diagnosis of diabetes
mellitus.

 FOR DETECTION OF BACTERIAS,FUNGI,VIRUSES

antigens on cell membrane surface results in additional mass loading, ultra-

sensitively detected by the device using nanochemical oscillator

The detection sensitivity is in the order of a single bacterium corresponding to a

mass of ~1 pg
 FOR CANCER DIAGNOSIS

When the cancer-associated molecules bind to the cantilevers, changes in

surface tension cause the cantilever to bend

The mass detection limitation of NEMS cantilevers is improved to the enumeration

of a single DNA molecule consisting of ~1600 base pairs and weighing ~1 ag
(atto = 10^18).
 NANOTUBE SENSOR
 SIZE / SHAPE

coated with strands of DNA

could detect molecules on the order of one

part per million
 PLATFORM

The Nano sensors could sniff molecules out of the air or

taste them in a liquid, suggesting applications ranging
from domestic security to medical detectors.
 FOR BLOOD GLUCOSE MONITARING

ENZYME GLUCOSE OXIDASE IS NON-COVALENTLY ATTACHED

BRINGS CATALYSATION OF GLUCOSE YIELDING HYDROGEN-

PEROXIDE

ENZYME IMMOBILISATION ALLOWS FLOW OF CURRENT

 NANO WIRE SENSOR
 STRUCTURE

SINGLE
CARBON
STRANDED NANOWIRE
NANOTUBE
DNA

DNA(DETECTOR)
NANOTUBE(TRANSMITTER)
 DETECTION OF SINGLE VIRUS

NANOWIRES CONFIGURED AS A FET

DETECTION OF SINGLE VIRUS ON RECEPTORS CHANGES

CONDUCTANCE

NANOSIZED WIRE REQUIRED FOR HIGH SIGNAL TO NOISE RATIO

 DETECTION OF BIOMOLECULE
SILICON NANOWIRE USED FOR
DETECTION OF PROTEIN KINASE VIZ CAUSE OF CHRONIC
LEUKEMIA

SILICON Nano sensor WITH PEPTIDE NUCLEIC ACID DISTINGUISHES

BETWEEN THESE MOLECULES
 TO IMPROVE SENSITIVITY OF CANTILEVER Nano sensor

 UNWANTED BIOFOULING (DETECTION OF NON-ADSORBING

MOLECULE)

 USUAL DESIGN PROBLEMS

 FLOW CONTROL

 RISK AND ECONOMICS