Professional Documents
Culture Documents
Arsalan PDF
Arsalan PDF
Arsalan PDF
Abstract: Background and objective: The incidence rate of type 2 diabetes is increasing day by day
at an alarming rate. Changing lifestyle and environment have contributory effect in increase rate of
type 2 diabetes mellitus. Hypothesis was that the AL-TENS (acupuncture like - TENS) on ST36 is a
complementary therapy for controlling plasma glucose in type 2 diabetes mellitus patients.
Methods: The study designed a single blind convenient clinical study of type 2 diabetes patients who
are already taking oral hypoglycemic pills to control blood glucose. In this study 30 patients were
selected on the basis of inclusion and exclusion criteria and divided into two equal groups; they were
assigned to receive either AL-TENS on the bilateral ST36 acupoints for 10 minutes for 7days or
placebo treatment 10 minutes for 7 days.
Result: There was significant improvement (P>0.05) in random blood sugar level of type 2 diabetes
mellitus.
Conclusion: It has been found AL- TENS on bilateral ST36 acupoints have an effect to control
plasma glucose level for type 2 diabetic mellitus patients and can be used without having any side
effect.
Key words: Type 2 diabetic mellitus, AL-TENS, Acupoint, plasma glucose level.
I. INTRODUCTION
The incidence of diabetic raising all over the world in an alarming rate, according to the
world health organization , diabetes mellitus affects at least 171 million people and
(1)
causes 3.2 million deaths, and 8700 deaths every day. A calculation of WHO shows
approximately 70% and 42% of cases of diabetes raises respectively in developed and
53
Asif Arsalan- MAINTENANCE OF BLOOD SUGAR LEVEL AMONG TYPE 2 DIABETES MELLITUS PATIENTS
BY USING AL-TENS OVER ACUPOINT - A PILOT STUDY
developing countries in 2030. This may causes to affect 366 million people by 2030 .
(1)
According to an estimate Bangladesh which had a population of 149.8 million in 2011 (2)
showed immense prevalence of diabetes that was 9% in 2006 to 2010(3), which will
further increase to 13% by 2030.(4)
In developing countries, the majority diabetes patient’s age are 35-64 years,
whereas people in developed countries suffer more above 64 years of ages. (5). Diabetics
affects both health status and the economic status of the country. The overall health care
costs of diabetes mellitus ranges from 2.5% to 15% of annual health care budgets of
developed and developing countries(6). The increasing rate of diabetes has put a burden
on the country as well as on the individual who have been suffering from diabetes.
There are several risk factors of type 2 diabetes including ageing, gender, country
and place of residence, society, socioeconomic status, lifestyle and obesity (7)
.The type 2
diabetes have some devastating complication that can lead to death due to
cardiocascular problem, renal failure etc(8). some vascular problem such as –
arthrosclerosis, retinopathy, nephropathy, foot complications, skin complications,
hearing loss, gastroparesis, ketoacidosis (DKA), neuropathy, nephropathy, peripheral
arterial disease , stroke can be happen for long suffering of diabetes(9)
There are some treatment available that includes both modern and ancient
treatment protocol and both chemical and organic remedy to control blood sugar level
and to prevent complication from the constant high blood sugar. There are several types
of oral pills and injectable insulin available that inhibit the release of glucose from the
liver, improve the cells sensitivity to insulin, slow the breakdown of starches and sugars
to glucose (10). Alternative treatment; medicinal herbs, nutritional supplements and hot
tub therapy has become popular from last several years, to treat diabetes. (11)
Acupuncture a traditional Chinese treatment now a days is going to be famous in
some countries to treat diabetes, Acupuncture is effective in both to treat diabetes and
preventing complications of diabetes.(12) The effects of acupuncture on diabetes have
been observed experimentally and clinically.(13) The above treatments are having some
certain side effect and are not so cost effective that all the patient who suffering from
diabetes can afford these.
So it’s necessary to introduce some cost effective and less side effect treatment for
the rapidly growing diabetes. In this study AL-TENS (acupuncture like TENS) which
have high frequency had been use to over bilateral ST36 acupoint to control the blood
glucose level in the people of Bangladesh. This is the very first time using of
Group A Group B
(n = 15) (n= 15)
Frequency 20 Hz
Frequency 0 Hz
Duration 10 minuets
Duration 10 minuets
7 days
7 days
III. RESULTS
The result was analyzed by using spss 16.0 version, pair and independent ‘t’ test was
use to analysis the result and the significant level was set at P > 0.05. There was no
significant difference of age between group A and group B (47.8+7.63 vs 49.93 + 6.71
years) [table;1, figure;2], baseline level of RBS (235.0 + 104.4 vs 220.67 + 70.04 mm/dl ),
and the duration of disease (4.28 + 1.88vs 5.36 + 2.20 years) [Table;2, Figure;3]. The
random blood sugar which was checked before and just after the stimulation shows the
significant difference in group A from day 1 pre to day 7 post of stimulation (235.0 +
104.4 vs 149.1 + 56.1 ) [table;3, figure;4] and not such statistical significant difference in
group B from day 1 pre to day 7 post of stimulation ( 220.6 + 77.04vs 245.8 + 51.39 )
[Table:4, Figure:5]
AMERICAN RESEARCH THOUGHTS- Volume 1 │ Issue 1 │ 2014
56
Asif Arsalan- MAINTENANCE OF BLOOD SUGAR LEVEL AMONG TYPE 2 DIABETES MELLITUS PATIENTS
BY USING AL-TENS OVER ACUPOINT - A PILOT STUDY
Table 1: Shows Comparison of mean and SD of age between the group A and group B.
Figure 2: Shows Comparison of mean and SD of age between the group A and group B.
Table 2: Comparison of mean, SD & SE in duration and level of RBS (base line) value between the
group A and group B.
Figure 3: Comparison of mean in duration and level of RBS (base line) value between the group A
and group B.
Table 3: Shows comparison of mean, SD & SE in day1 pre and day 7 post RBS level in the group A.
Figure 4: Shows comparison of mean &SD in day1 pre and day 7 post RBS level in the group A.
Table 4: Shows comparison of mean, SD & SE in day1 pre and day 7 post RBS level in the group B.
Figure 5: Shows comparison of mean &SD in day1 pre and day 7 post RBS level in the group B.
IV. DISCUSSION
Whereas other studies used more points and they had also taken longer duration of
stimulation. This duration and the acupoint is suitable for patients as well as for
Physiotherapist and it is very first time, that electrotherapy modalities used in the field
of physiotherapy to reduce blood glucose Bangladesh so far.
Manual needling, and electro-acupuncture, is the most commonly used modality
today (G. A. Ulett, et al; 1998)16. In this study electrotherapy modality is used to apply
electrical stimulation on acupoint via skin electrodes. This was noninvasive and easy
method to use. Previous study which stimulate the ST36 and SP6 bilaterally on the non-
diabetic patient shows the transcutaneous electrical nerve stimulation on that point
improve the insulin resistance during the general anesthesia (Kee-Ming Man et al;
2010)17. As the animal and the non-diabetic patients experiment has shown different
mechanisms but both are related to decrease the blood glucose level. As this was the
very first study done on type2 diabetic patient, so actually what mechanism were
happening in the type 2 diabetic body is still unknown.
The beta cells of the pancreas are responsible for the secretion of insulin, the
hormone that facilitates the transport of energy-producing glucose into the body's cells.
In type 2 diabetes, dysfunction of these insulin-producing cells combined with a
decrease in the insulin response of individual cells, results in increased blood sugar
levels. The progression of beta-cell dysfunction associated with increased insulin
resistance is the usual indication for the use of oral anti-diabetic medications. With
effective oral anti-diabetic medication, hyperglycemia or high blood sugar levels can be
corrected. Generally people who suffering from type 2 diabetics takes various type of
medicines by the advice of physicians to control their blood glucose level. The
medicines that commonly use in diabetic mellitus have property of insulin
secretagogues and Insulin sensitizers.
The insulin secretagogues are a group of oral medications that stimulate the beta
cells of the pancreas to secrete more insulin. They also decrease glucose production by
the liver and enhance the burning of glucose into usable energy forms by individual
muscle fibers. (Alvin 2008)18. Insulin sensitizers are a group of oral medications that
enhance the action of the insulin in the body.
From the previous study which had done on the animals and non-diabetic
patients with the electeopuncture and transcutaneous electrical nerve stimulator have
shown the similar effect of medicine that it helps to improves the insulin resistance, to
enhance insulin synthesis, to increase the number of receptors on target cells, and to
accelerate the utilization of glucose.(12)
The TENS (transcutaneous electrical nerve stimulation) is very common and
available modality which is used in physiotherapy department. This was cost effective
and less time consuming procedure in the blood glucose reduction. During the
treatment subjects who have mild to moderate pain at their leg also reporting less or no
pain at their leg after completion of the treatment. Commonly people who suffering
from diabetics takes medicine or insulin to control the blood glucose level which have
some side effect after long time using, but the TENS have no such type of side effect on
human body. This new approach of reduction blood glucose level gives a new
treatment procedure and opens a new use of TENS rather than to traditional use in pain
management and also which is free from any side-effect to the diabetic patient. So
transcutaneous electrical nerve stimulation can be used as a safe and new method to
control the blood glucose level for whom suffering from type 2 diabetes mellitus.
The sampling was selected in convenient method; this could be a random method for
the future study, as well as the sample size can be increase as this was a small sample
size. The parameter used in this study was only random blood sugar in future study
there can be more parameter use in future. Some other type diabetes patients can be
included in future to see the effect of TENS on the other type of diabetes.
VI. CONCLUSION
REFERSENCES
1. WHO: World health organization (2006). Global strategy on diet, physical
activity and health ; accessed 1 May 2006
http://www.who.int/dietphysicalactivity/publications/facts/diabetes/en/1.05.2006
2. Bangladesh population and housing census 2011. (2012). Dhaka: Bangladesh
Bureau of Statistics, Government of the People’s Republic of Bangladesh.
3. Saquib, N., Saquib, J., Ahmed, T., Khanam, M.A., Cullen, M.R. (2012).
Cardiovascular diseases and type 2 diabetes in Bangladesh: a systematic review
and meta-analysis of studies between 1995 and 2010. BMC Public Health, 12, 434
http://dx.doi.org/10.1186/1471-2458-12-434 pmid: 22694854
4. International Diabetes Federation (IDF) .Country estimates table 2011. IDF
diabetes atlas. 6th ed. 2012. Accessed 7 June 2013
http://www.idf.org/sites/default/files/EN_6E_Atlas_Full_0.pdf.
5. Wild, S., Roglic, G., Green, A., Sicree, R., King, H. (2004). Global prevalence of
diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care. May;
27(5), 1047-53.
6. Animesh Bishwas. (2006). Prevention of type 2 diabetes – life style modification with
diet and physical activity vs physical activity alone -A comparative literature review.
Master of public health education, Department of Public Health Science,
Karolinska Institute.
7. Gadsby, R. (2002). Epidemiology of diabetes. Advanced drug delivery reviews, 54(9),
1165-72.
8. Kumar, P. & Clark, M. (2005). Clinical Medicine, 6th edition, Spain, Elsevier
limited.
9. Levin, M. E. and Pfeifer, M. A. 2009. Uncomplicated Guide to Diabetes'
Complications, 3rd Edition.
10. Venkataraman, C., Sagar, A., Habib, G., Lam, N., and Smith, K., (2010). The
Indian national initiative for advanced biomass cookstoves: the benefits of clean
combustion. Energy for Sustainable Development. International Journal of Diabetes
in Developing Countries, 14 (2), 63–72.
11. Laakso. (2008) Essential hypertension and insulin resistance in non-insulin-
dependent diabetes. N Engl J Med, 19 (6), 518–526.
12. Hu, H. (1995). A review of treatment of diabetes by acupuncture during the past
forty years. J. Tradit. Chin.Med., 15, 145–154.
13. Wei, J. (1985). Changes of plasma insulin level in diabetics treated with
acupuncture. J Tradit Chin Med, 5, 79-84.
14. Ingle, P. V., Samdani, N. R., Patil, P. H., Pardeshi, M. S., and Surana, S. J. (2011).
Application of Acupuncture Therapy In Type 2 Diabetes Mellitus Patients.
Pherma Science Monitor an International Journal Of Pharmaceutical Science, 2,(1).
15. Chang, S.L., Lin, K.J., and Lin, R.T. (2006). Enhanced insulin sensitivity using
electroacupuncture on bilateral Zusanliacupoints (ST 36) in rats. Life Sci, 79, 967–
971.
16. Ulett, G. A., Han, S., and Han, J.-S. (1999). Electroacupuncture: mechanisms and
clinical application. Biological Psychiatry, 44. (2), 129–138.
17. Man, Kee-Ming, and Man, Samantha S. (2010) Transcutaneous electrical nerve
stimulation on ST36 and SP6 acupoints prevents hyperglycaemic response
during anaesthesia: a randomised controlled trial. Eur J Anaesthesiol 27.
18. Fauci, A. S., Braunwald, E., Kasper, D. L., Hauser, S. L., and Longo, D. L.
(2008). HARRISON’S Principles of internal medicine, McGraw-Hill professional. 17th
edition. Volume 2.