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Bone tumor • Primary malignant bone tumors are

rare.
Definition:
• Secondary tumors are more common,
• is a neoplastic growth of tissue in bone.
especially in the elderly
Abnormal growths found in the bone
can be either benign (noncancerous) Symptoms:
or malignant (cancerous)
• Most patients with a bone tumor will
• It may weaken the bone, causing it to experience pain in the area of the
break (fracture) tumor. The pain is generally described
as dull and achy. The pain often
A bone lytic lesion -is an area where part of a
awakens the patient at night.
bone appears to have been dissolved or "eaten
away". • Although tumors are not caused by
trauma, occasionally injury can cause a
Bone tumors may be classified as:
tumor to start hurting. Injury can cause
• primary tumors- which originate in a bone that is already weakened by a
bone or from bone-derived cells and tumor to break
tissues.
• Occasionally, benign tumors may be
• secondary tumors -which originate in discovered incidentally when X-rays are
other sites and spread to the skeleton taken for other reasons, such as a
sprained ankle or rotator cuff problem.
Etiology:
Diagnosis:
• Genetics defects passed down through
families • X-rays

• Radiation • Computed tomography (CT) scans

• Injury • Magnetic resonance imaging (MRI)


scans
Epidemiology:
• Radionuclide bone scans
• In adults, over 40% of primary bone
cancers are chondrosarcomas. This is • Positron emission tomography (PET or
followed by osteosarcomas (28%), PET) scans
chordomas (10%), Ewing tumors (8%),
Prognosis:
and malignant fibrous
histiocytoma/fibrosarcomas (4%). The • The outlook depends on the type of
remainder of cases are several rare tumor. The outcome is expected to be
types of bone cancers. good for people with noncancerous
(benign) tumors, although some types
• In children and teenagers (those
of benign tumors may eventually
younger than 20
become cancerous (malignant). With
years), osteosarcoma (56%) and Ewing
malignant bone tumors that have not
tumors(34%) are much more common
spread, most patients achieve a cure,
than chondrosarcoma (6%).
but the cure rate depends on the type
of cancer, location, size, and other tissue around it. The excised bone is
factors. replaced with a metallic implant
(prosthesis) or bone transplant.
Complication:
B. Amputation- removes all or part of an
• Pain
arm or leg when the tumor is large and/or
• Reduced functions, depending on the nerves and blood vessels are involved.
tumor

• Side effects of chemotherapy

• Spread of the cancer to other nearby


tissues (metastasis)

Treatment:

 Nonsurgical Treatment

 Benign Tumors- can be treated


effectively with medication

 Malignant Tumors

A. Radiation Therapy-uses high-dose x-rays


to kill cancer cells and shrink tumors.

B. Systemic Treatment (Chemotherapy)-


often used to kill tumor cells when they
have spread into the blood stream but
cannot yet be detected on tests and scans.
Chemotherapy is generally used when
cancerous tumors have a very high chance
of spreading.

 Surgical Treatment:

 Benign Tumors

• Sometimes the doctor may recommend


removing the tumor (excision) or some
other treatment techniques to reduce
the risk of fracture and disability

 Malignant Tumors

A. Limb Salvage Surgery-This surgery


removes the cancerous section of bone but
keeps nearby muscles, tendons, nerves, and
blood vessels. If possible, the surgeon will
take out the tumor and a margin of healthy

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