The document discusses two species of filoviruses: Marburg virus and Ebola virus. Both viruses are single-stranded RNA viruses that cause viral hemorrhagic fever in humans. They replicate extensively in endothelial cells which leads to cytokine storms and widespread tissue damage. This causes symptoms like nausea, diarrhea, and hemorrhaging. Diagnosis is usually done via PCR or ELISA tests. There is no vaccine yet, but treatment focuses on supportive care and people who come into contact with infected patients are quarantined to prevent spread.
The document discusses two species of filoviruses: Marburg virus and Ebola virus. Both viruses are single-stranded RNA viruses that cause viral hemorrhagic fever in humans. They replicate extensively in endothelial cells which leads to cytokine storms and widespread tissue damage. This causes symptoms like nausea, diarrhea, and hemorrhaging. Diagnosis is usually done via PCR or ELISA tests. There is no vaccine yet, but treatment focuses on supportive care and people who come into contact with infected patients are quarantined to prevent spread.
The document discusses two species of filoviruses: Marburg virus and Ebola virus. Both viruses are single-stranded RNA viruses that cause viral hemorrhagic fever in humans. They replicate extensively in endothelial cells which leads to cytokine storms and widespread tissue damage. This causes symptoms like nausea, diarrhea, and hemorrhaging. Diagnosis is usually done via PCR or ELISA tests. There is no vaccine yet, but treatment focuses on supportive care and people who come into contact with infected patients are quarantined to prevent spread.
The document discusses two species of filoviruses: Marburg virus and Ebola virus. Both viruses are single-stranded RNA viruses that cause viral hemorrhagic fever in humans. They replicate extensively in endothelial cells which leads to cytokine storms and widespread tissue damage. This causes symptoms like nausea, diarrhea, and hemorrhaging. Diagnosis is usually done via PCR or ELISA tests. There is no vaccine yet, but treatment focuses on supportive care and people who come into contact with infected patients are quarantined to prevent spread.
Genus Species Morphology Phathogenesis Clinical Diagnosis &
syndrome Treatment Filoviridae Marburg Virus Rna, + sense, Massive replication at Same as flu. PCR Known as (panjang :665) single strands. endotel, monosit, (nausea, ELISA African Dengue Epidem : rare case, Diameter 80nm makrofag, dendrit dhiarrhea, Zimbabwe and kenya. (murray) 70nm vomiting, Viral destroyed (long filament) Reservoir : African (jawetz). Monosit elicit cytokines dyspnea, when dipanaskan green mongkey, Panjang 800- storms (superantigen headache) dalam 60 derajat Cercopithecus 1400 nm like)extensive tissue celsius selama 30 aethiops Necrosis in parenchyma Viral menit dnegna UV Nucleocapsid liver, spleen, lymph node, haemmorhagic dan iradiasi Ebola Virus helical lung fever Gamma dan (panjang : 805) enveloped pelarrut lipid dan Epidem: zaire, sudan, contain 1 Endothelial protein Death 90% pembilas dan Liberia,sieraaleone, glycoprotein. adhesion will interfered, disinfektan guinea Glycoprotein cause cytolysis BSL 4 phenolic Reservoir : kera menyusun duri widespread endothelial sinomolgus ( Macaca trimer. vascular leakage Fascicularis) hypovolemic shock and Traeatment : edema (was classified as 1. antibody rhabdoviridae) Gp can inhibit neutrophil containing and antibody action serum They maybe endemic 2. Artificially in BAT and WILD Viral protein can inhibit produced MONGKEY interferon production and antibody action. ZAMPP 3. Interferon Ebola virus will bind to 4. Ribafirin niemann-pick c1 (NPC1), Hewan di slughter cholesteros transfer protein and TIM1 (t-cell Human immunoglobulin and quarantined mucin domain one) a same receptor as hepatitis A
Spread with contact
infected blood( human syringe) or oral secretion (biten by hewan) penjaga monyet dan dokter hewan.