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  • Bacille-Calmett Guerin Vaccine & Scar

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    Farah Syakirah Al-Firas
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    The document discusses the Bacille-Calmett-Guerin (BCG) vaccine and the scar it produces. The BCG vaccine uses live attenuated strains of tuberculosis to provide 50-80% protection against pulmonary TB and 80% protection against TB meningitis. The BCG scar acts as a surrogate marker for vaccination and checking immunity. Factors like age, gender, and vaccine quality can affect scar development. Studies show administering 0.1 ml of the vaccine at birth results in the highest efficacy rates of 97.1-100%.

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    all about bcg

    Original Title

    BCG Vaccine

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    The document discusses the Bacille-Calmett-Guerin (BCG) vaccine and the scar it produces. The BCG vaccine uses live attenuated strains of tuberculosis to provide 50-80% protection against pulmonary TB and 80% protection against TB meningitis. The BCG scar acts as a surrogate marker for vaccination and checking immunity. Factors like age, gender, and vaccine quality can affect scar development. Studies show administering 0.1 ml of the vaccine at birth results in the highest efficacy rates of 97.1-100%.

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    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
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    Download as pdf or txt
    17 views6 pages

    Bacille-Calmett Guerin Vaccine & Scar

    Uploaded by

    Farah Syakirah Al-Firas
    The document discusses the Bacille-Calmett-Guerin (BCG) vaccine and the scar it produces. The BCG vaccine uses live attenuated strains of tuberculosis to provide 50-80% protection against pulmonary TB and 80% protection against TB meningitis. The BCG scar acts as a surrogate marker for vaccination and checking immunity. Factors like age, gender, and vaccine quality can affect scar development. Studies show administering 0.1 ml of the vaccine at birth results in the highest efficacy rates of 97.1-100%.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as pdf or txt
    of 6

    Bacille-Calmett

    Guerin
    Vaccine & Scar
    OVERVIEW GIVEN

    ▪ Live attenuated vaccine against


    vaccine tuberculosis ▪ New borne-adolescent
    ▪ Strains ▪ Intradermal
    - Copenhagen-Danish 1331 - Injection at deltoid
    - Pasteur
    - Glaxo
    ▪ Stored at 2-8C
    PROTECTION

    ▪ 80% - TB Meningitis,
    military TB
    ▪ 50% - Pulmonary TB

    2
    BCG Scar
    Surrogate marker of vaccination
    Simplest & successful way of vaccination
    checking

    Not affected by:


    ▪ Age

    ▪ Gender

    Size: 3-4 mm

    3
    Development Strain Dosage injected
    Administration
    mode
    of BCG Scar

    Absence of Vaccine quality Proper transport

    scar may
    because of
    Undiagnosed underlying Storage
    immune disorder in infants

    4
    Correlation
    Baby Group A B C
    dosage, age
    & efficacy Dose 0.05 ml 0.1 ml 0.1 ml

    Age Newborn Newborn 4-6 weeks

    Efficacy 93.8% 100% 97.1%

    Conclusion: Most effective dosage is 0.1 ml & should be given as


    soon as given birth for maximum protection.

    5
    REFERENCE

    ▪ Dhanawade, Kumbhar, Gore, Patil, Scar formation and


    tuberculin conversion following BCG vaccination in infants:
    A prospective cohort study, Journal of Family Medicine and
    Primary Care 4(3) , (2015), 384–387
    ▪ https://www.youtube.com/watch?v=UYV6MJhRGkQ

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