PREDISPOSING

REMARKS RATIONALIZATION JUSTIFICATION

FACTORS

According to a research titled

“Epidemiology of non-
Hodgkin’s lymphoma (NHL): The patient is 48 years
Age trends, geographic old. The occurrence of
distribution, and etiology”, In this condition is most
>55 ABSENT unlikely especially he
elderly persons pronounced
increases occur, especially is still in his late 40’s.
among each successive age
group >55 years, regardless
of gender and race.

According to a research titled

“Epidemiology of non-
Hodgkin’s lymphoma (NHL):
trends, geographic Our patient is male.
distribution, and etiology”, Making him more
Sex PRESENT Although a NHL increase has predisposed to have
been noted for both genders, Non-Hodgkin’s
lymphoid cancers are more Lymphoma.
frequent in males than
females throughout all age
groups and across virtually all
cancer registries in developed
countries.

Race ABSENT Based on research,

whites are more likely
According to a research titled to have lymphoma
“Epidemiology of non- compared to other
Hodgkin’s lymphoma (NHL): races.
trends, geographic
distribution, and etiology”,
Total NHL incidence rates
were 40–70% higher among
whites than blacks, with a
 white to black ratio of 2–3 for
follicular lymphoma and 1–2
for most other subtypes.
Using the largest population-
based dataset (Swedish
Family-Cancer Database), a
recent analysis has suggested
Hereditary ABSENT familial risk for almost all
cancer sites.
Source: Epidemiology of
non-Hodgkin’s lymphoma
(NHL): trends, geographic
distribution, and etiology
PRECIPITATING
REMARKS RATIONALIZATION
FACTORS
According to a research titled
“Epidemiology of non-
Hodgkin’s lymphoma (NHL):
trends,
geographic distribution, and
etiology”, Immunosuppresed
individuals (AIDS,
Immunosuppression PRESENT
Congenital
Immunodeficiency,
immunosuppressive drug
therapy, Autoimmune
Disorders, and Celiac
Disease) have higher risk of
acquiring NHL. Generally,
these factors alter the immune
system and this may be the
cause of mutation.
Based on the
interview and the date
gathered from the
patient, it is only he
who had this
condition or any other
malignant tumors
within his family and
his lineage.
JUSTIFICATION
The patient’s ailment
has metastasized to
the bone marrow. One
function of the bone
marrow is to produce
stem cells that would
form into any of the
blood components,
thus decreasing the
production of WBCs
causing the
immunosuppression.
Patient also is
currently under
chemotherapy and
may contribute to the
immunosuppression.
 According to a research titled
“Epidemiology of non-
Hodgkin’s lymphoma (NHL):
trends, geographic
distribution, and etiology”,
Infections such as HTLV-1,
EBV, Helicobacter pylori The patient did not
Infection ABSENT (HP) and Campylobacter experience any of the
jejuni (C. jejuni), Hepatitis C said infections.
virus and chlamydia psittaci
have higher risk of acquiring
NHL. Generally, these agents
attack the lymphocytes which
alter their function and cause
a failure of recognition of
infected cells.

Exposure to PRESENT As iterated, the

environmental patient works as the
agents/occupational According to a research titled driver of their own
risk “Epidemiology of non- delivery service.
Hodgkin’s lymphoma (NHL): More often than not,
trends, he is exposed to direct
geographic distribution, and sunlight especially
etiology”, With an analysis of when he is driving.
occupational exposures, an
increased risk among persons
exposed to insecticides,
pesticides, and dust was
found. People

employed in the agricultural,

forestry, fishing, construction,

paper, wood, or leather

industries were observed to be
at an increased risk. Farmers
have repeatedly been reported
to be at risk, possibly due to
their pesticide usage and their
 exposure to agricultural
chemicals. Similar results
were also found with
exposure to Ionizing and UV
radiation and Hair dyes.
These agents are carcinogenic
which contributes to an
increase risk for acquiring
NHL.

In a large prospective cohort

study height, weight, body
mass index, waist/hip ratio,
and physical activity were not
associated with NHL risks.
This is consistent with several
other studies, but in contrast
to a Swedish cohort study that
found obese women to be at
Anthropometric excess risk of developing
ABSENT
factors/nutrition NHL. High intake of fruit and
vegetables, particularly
cruciferous vegetables and
fibers, has been shown to be
associated with a lower risk.
The patient is very
careful especially
regarding his diet. He
and his family knows
and are aware that he
is diabetic and as a
result they are very
careful and vigilant
especially on their
diet.

Source: Epidemiology of non-

Hodgkin’s lymphoma (NHL):
trends, geographic
distribution, and etiology

Diabetes is associated with a

moderately increased risk of Our patient was
NHL, which is consistent with
diagnosed diabetic,
other reported associations
Diabetes Mellitus Present between diabetes and therefore making him
malignancies. more susceptible of
NHL.
Source:
http://care.diabetesjournals.o
rg/content/31/12/2391.full
 SYMPTOMS REMARKS RATIONALE

Lymphoma usually only causes pain when it swells up to

One or more such a point that it's putting pressure on your nerves.
painless swellings Present
Source: http://www.medicnet.org/cancer/01/archives-
in the neck,
lymphoma.htm
armpit or groin

If the lymph nodes are situated inside the chest or abdomen

Chest pain,
are enlarged, other problems like backache and
coughing or Present
breathlessness can also be experienced.
trouble breathing
Source: http://www.checkcancersymptoms.com/lymph-
node-cancer-symptoms.html

Fatigue is the result of low hemoglobin caused by

decreased production of RBC in the bone marrow.
Fatigue Present
Source: http://www.medicinenet.com/non-
hodgkins_lymphomas/page3.htm#2whatare

A fever is one of the body's immune responses that attempt

to neutralize a bacterial or viral infection. A fever can be
Fever Present
caused by many different conditions ranging from benign
to potentially serious.

Source: http://en.wikipedia.org/wiki/Fever

It is a compensation for a high body temperature.

Night sweats Present Source: http://night-sweats.net/causes-of-night-
sweats.html

Weight loss Present

This belongs to the symptoms B, meaning some may have

it, but most don’t. Weight loss is the result of massive fluid
 loss and change in appetite.

Source: http://www.cancerhelp.org.uk/type/non-hodgkins-
lymphoma/about/symptoms-of-non-hodgkins-lymphoma