STI COLLEGE SOUTHWOODS

Lot 2A Maduya, Carmona, Cavite

COLLEGE OF HEALTH CARE

DRUG STUDY

Side Effects / Nursing

Mechanism of Contraindicatio
Generic Name Brand Name Classification Dosage Indication Adverse Implications and
Action n
Effects Responsibilities
CEFUROXIME Anti- Infectives 750 mg TIV Inhibits DNA • CNS: •Advise Patient not
Brands : synthesis by susceptible Hypersensitivity to Headache to take drugs with
Axacef tab inhibiting DNA infections cephalosporins • CV: dairy or Caffeinated
Axim tab gyrase in >Resp tract Orthostatic products
Ceflour Film- susceptible gram Hypotension •Inform physician if
infections
coated tab negative and • EENT: allergies or rashes
Ceflour IM/IV gram positive >Surgical Blurred Vision abruptly develop
inj Cefuroxim organisms prophylaxis • GI:
Stada film- Nausea and
coated tab Vomiting,
Cefuroxime Diarrhea,
Sandoz vial constipation
Cefuroxime • OTHER:
Shenzhen vial Taste
Pan-
Cefuroxime
vial Quali-
Cefurnat tab
Sefuxim Film-
coated tab
Zinacef IM/IV
inj Zinacef IV
inj Zinnat
film-coated tab
Zinnat susp
Metronidazole
Flagyl -S susp Anti- Infectives 500 mg SD Metronidazole is Tab: Should be taken
Flagyl tab (ANST) converted to History of GI disturbances with food.
Frotin sugar- reduction hypersensitivity to e.g. nausea, Susp: Should be taken
coated tab metronidazole or unpleasant
products that on an empty stomach.
Frotin tab
interact with DNA other metallic taste, (Take at least 1 hr
Frotin vag
supp to cause nitroimidazole vomiting, before meals.)
Gynoplix destruction of derivatives. diarrhoea or
pessary helical DNA Pregnancy (1st constipation. Patients with CNS
Metrogyl tab structure and trimester) and Furred tongue, diseases; discontinue
strand leading to a lactation. glossitis, and IV therapy if
protein synthesis stomatitis due to abnormal neurologic
inhibition and cell overgrowth of symptoms occur.
death in Candida. Rarely, History of seizure
susceptible antibiotic- disorder. Evidence or
organisms. associated colitis. a history of blood
Weakness, dyscrasias; perform
dizziness, ataxia, total and differential
headache, leukocyte counts
drowsiness, before and after
insomnia, changes treatment. Severe
in mood or mental hepatic impairment;
state. monitor plasma levels.
Predisposition to
oedema (inj contains
sodium). Prolonged
use may result in
fungal or bacterial
superinfection.

Naprex® [amp] .
Injection: Oral Pain or
Hypersensitivity to
fever or both Paracetamol is
Based in 10 Paracetamol paracetamol.
in infants, relatively nontoxic
Analgesics (Non- mg/kg body exhibits analgesic
childn & in therapeutic
Opioid) & weight/day, to and antipyretic Repeated
adults. Inj doses.
Antipyretics be given via activity by High-grade administration is Dermatologic
slow IV push inhibiting fever, contraindicated in reactions eg,
 or via deep prostaglandin conditions pruritic
IM inj, every synthesis. It where a rapid patients with maculopapular
4-6 hrs a day, produces predictable anemia, cardiac, rash and urticaria
blood level is
or analgesia by pulmonary, renal have been
required in
approximately elevating the pain predisposed and hepatic reported.
as follows: threshold and childn to disease. Sensitivity
antipyresis febrile reactions eg,
through action on convulsions & laryngeal edema,
the hypothalamic post-op angioedema and
heat-regulating patients anaphylactoid
where oral
center. reactions may
medication is
not possible occur rarely.
Prolonged
administration of
large doses of
paracetamol may
lead to
thrombocytopenia,
leukopenia,
agranulocytosis
and pancytopenia

Aciloc® [amp] Peptic ulcer, Transient &

yzolt Tablet, 50 mg IV GERD, reversible changes
Extended selected Pregnancy & in liver function
H2 blockes
Release cases of lactation tests. Reversible
blocks acid
Tramadol Hcl persistent
receptors that hepatitis
Tablet dyspepsia,
Antacids, produces acids (hepatocellular,
Tramadol Zollinger-
Hydrochloride Antireflux Agents Ellison hepatocanalicular
Tablet & Antiulcerants syndrome, or mixed) with or
Tramadol stress without jaundice.
Hydrochloride ulceration, & Skin rash.
Tablet, Coated in patients at
Tramadol risk of acid
Hydrochloride aspiration
Tablet, Film during
Coated anesth, reflux
Ultram Er esophagitis.
Tablet,
 Extended moderate to
Tramadol severe pain Sweating,
Release 50 mg IV dizziness, nausea,
Ultram Tablet, Suicidal patients, vomiting, dry
Orally Tramadol inhibits acute alcoholism; mouth, fatigue,
Disintegrating reuptake of head injuries;
norepinephrine, asthenia,
raised intracranial somnolence,
Analgesics serotonin and
(Opioid) enhances pressure; severe confusion,
serotonin renal impairment; constipation,
release. It alters lactation. flushing,
perception and headache, vertigo,
response to pain
tachycardia,
by binding to
mu-opiate palpitations,
receptors in the miosis, insomnia,
CNS. orthostatic
hypotension,
seizures, CNS
stimulation e.g.
hallucinations.
Potentially Fatal:
Respiratory
depression

Aeknil® [amp] Nausea, vomiting,

Paracetamol Pyrexia of abdominal pain,
produces unknown Hematological, diaphoresis,
analgesia by origin. Fever skin & other generalized
& pain allergic reactions.
raising the weakness and
associated w/
threshold of the common lethargy. If an
pain center in the childhood overdosage of
Antipyretic,
brain and by disorders, paracetamol is
analgesic
obstructing tonsillitis, suspected, blood
impulses at the upper resp should be
pain-mediating tract withdrawn
infections
chemoreceptors. immediately for
post-
The drug immunization
paracetamol
produces reactions, plasma assay,
antipyresis by an after without regard to
action on the tonsillectomy the presence or
hypothalamus; & other absence of
heat dissipation is conditions. symptomatology.
increased as a Prevention of
febrile
result of
convulsion.
vasodilation and Headache,
increased cold,
peripheral blood sinusitis,
flow. muscle pain,
arthritis &
toothache.