SEEKING

PARTICIPANTS CONTACT
You may be eligible if
INFORMATION
you:
Clinical Neuroelectrophysiology
 Are 18-65 years old
and Cognitive Research
 Were previously Laboratory
diagnosed with
depression, and Located in the Royal Ottawa
experienced at Mental Health Centre (ROMHC)
least 2 depressive Clinical Neuroelectrophysiology &
episodes 1145 Carling Avenue
Ottawa, ON K1Z 7K4 Cognitive Research Laboratory
 Are not currently Phone: 613-722-6521 ext. 6490
depressed 3rd Floor – Rm. 3128

 Are not currently If you are interested in

taking any participating, please contact
antidepressant us by email or phone
medication
Emma Lynn (Graduate Student)
 Have no history of Emma.Lynn@theroyal.ca
previous drug or 613-722-6521 ext. 6757
alcohol abuse
Courtney Lord (Research
Assistant)
Courtney.Lord@theroyal.ca
613-722-6521 ext. 6490
Study Details
Why are we doing this study?
People with depression often have
problems with attention and
concentration even after they are no
longer depressed. Antidepressant
medications do not always treat
these lingering problems. This study
will assess whether a natural
supplement, CDP-choline, has a
positive effect on concentration,
learning and memory.
What does the study involve?
We are recruiting participants to
examine the effects of CDP-choline
versus a placebo (sugar pill) on
cognition in individuals who were
previously diagnosed with
depression, but are not currently
depressed (i.e. are in remission).
CDP-choline is a natural supplement
that may have pro-cognitive effects.
Cognition will be assessed in this
study via a series of computerized
tasks.
This study also includes an optional
brain imaging component.
OPTIONAL BRAIN
CDP-choline is a natural IMAGING COMPONENT
supplement that is already
in the body and that is in
many daily consumed food
products such as eggs and
peanut products.
.
Your Role as a Participant
Attend a total of three testing What is an EEG?
sessions, including An electroencephalogram (EEG) is a
 A baseline appointment where recording of the electrical activity
you will be assessed by a generated by a person’s brain. By
psychologist for eligibility, fill out placing electrode sensors on the
questionnaires and complete scalp, we are able to record this
computerized cognitive tasks activity.
 Two more testing sessions
where you will fill out What is fMRI?
questionnaires and complete
Functional magnetic resonance
computerized cognitive tasks.
imaging (fMRI) is another way to
You will take CDP-choline (or
measure brain activity – it works by
placebo) capsules before the
measuring changes in blood flow in
second and third testing
the brain.
sessions
Optional: undergo brain imaging
scans (electroencephalogram [EEG] Both EEG and fMRI procedures
and functional magnetic resonance are non-invasive and have been
imaging [fMRI]) during the second and proven to be safe.
third sessions.