ABSTRACT

THE REPRESENTATION OF MEAN PLATELET VOLUME IN SEVERITY

OF ACUTE ISCHEMIC STROKE BASED ON CRITERIA NATIONAL
INSTITUTES OF HEALTH STROKE SCALE IN RSUD ARIFIN ACHMAD
RIAU PROVINCE.

By
Vebi Adrias

World Health Organization (WHO) elaborates stroke as disorder of brain

functional which features a sudden onset with clinical manifestasions such as
disorder of the cerebral functions, both focal and global. 500.000 of Indonesian
had stroke, and about 25% died, the rest are had mild to severe disablement. Mean
platelet volume (MPV) is an indicator of platelet reactivity. Platelets play an
important role in the pathophysiology of ischemic stroke. This research is aimed to
know the determine representation of MPV in severity of acute ischemic stroke
based on criteria NIHSS in RSUD Arifin Acmad Riau Province in the period of
Desember 2016–February 2017. The result showed normal MPV are found in
acute ischemic stroke patients with NIHSS criteria were as many as 22 people
(48.88%), a high MPV values are found in patients with ischemic stroke with
NIHSS criteria weigh as much as 3 people (6.66%). In conclusion there are
representation of MPV in severity of acute ischemic stroke based on criteria
NIHSS.

Keywords: MPV, acute ischemic stroke, severity

iv
 ABSTRAK

GAMBARAN MEAN PLATELET VOLUME PADA SEVERITAS PASIEN

STROKE ISKEMIK AKUT BERDASARKAN KRITERIA NATIONAL
INSTITUTES OF HEALTH STROKE SCALE DI RSUD ARIFIN ACHMAD
PROVINSI RIAU

Oleh
Vebi Adrias

World Health Organization (WHO) menjelaskan stroke adalah gangguan

fungsi otak yang onsetnya mendadak dengan manifestasi klinis berupa gangguan
fungsi serebral baik fokal maupun global. Di Indonesia diperkirakan 500.000
penduduk terkena serangan stroke dan sekitar 25% orang meninggal dan sisanya
mengalami cacat ringan sampai berat. Mean platelet volume (MPV) adalah sebuah
indikator dari fungsi platelet atau aktivitasnya. Platelet memainkan peran penting
pada patofisiologi stroke iskemik. Penelitian ini bertujuan untuk mengetahui
gambaran mean platelet volume pada severitas pasien stroke iskemik akut
berdasarkan kriteria NIHSS di RSUD Arifin Achmad Provinsi Riau periode
Desember 2016 – Februari 2017. Hasil penelitian didapatkan bahwa nilai MPV
yang normal paling banyak di temukan pada pasien stroke iskemik akut dengan
kriteria NIHSS sedang sebanyak 22 orang (48,88%), sedangkan nilai MPV yang
tinggi paling banyak di temukan pada pasien stroke iskemik dengan kriteria NIHSS
sangat berat sebanyak 3 orang (6,66%). Kesimpulan dari penelitian ini adalah
terdapat gambaran gambaran mean platelet volume pada severitas pasien stroke
iskemik akut berdasarkan kriteria NIHSS.

Kata kunci : MPV, Stroke iskemik akut, Severitas