KIKUCHI-FUJIMOTO DISEASE : CASE REPORT AND LITERATURE

REVIEW

Gasha Aryapratama1, Elisabeth Margareth1, Tiur Herlina Situmorang2, Togar

Mulia Simanjuntak2

1
General Practitioner, Departemen of Surgery, PGI Cikini Hospital in Central

Jakarta

2
General Surgeon, Departemen of Surgery, PGI Cikini Hospital in Central Jakarta

3
Oncologist Surgeon, Departemen of Surgery, PGI Cikini Hospital in Central

Jakarta

Abstract

Background :

Kikuchi-fujimoto disease (KFD) is self limiting disease which exact cause

is unknown. Clinical manifestations of KFD are very similar with most chronic

diseases which are fever and lymphadenopathy. Hence, it is often misdiagnosed as

tuberculosis infection, lymphoma, SLE and so forth.

Case Report:

A 34 year-old woman presented to PGI Cikini Hospital with a history of

intermittent fever for 2 weeks. She also noticed there were painful bumps on her

neck during this period. She has not remarkable medical history nor history of

Tuberculosis infection. Excisional biopsy and histopathological examination later

performed and showed necrotizing cells with leucocytes and histiocytes which is

consistent with KFD findings.

Conclusion:

KFD is a rare disease. The definitive diagnosis can be established by

histopathological examination. It is important to determine the diagnosis to prevent

overtreatment and accomplish better outcome.

Keyword: Lymphadenopathy, Kikuchi-Fujimoto disease, Tuberculosis, Lymphoma