Multiple Choice Question in Pharmacy

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Q: 1 In the stability of emulsion, which important instability step should be prevented?

A. Breaking
✓ Correct Ans B. Coalescence
C. Flocculation
D. Creaming

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Section: Mock test 4 Question Type: Multiple Choice (Radiobutton) QID: 238

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Q: 2 Brownain movement of partilce in suspenstion cause

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A. assist sedimentation
B. promote sedimentation

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✓ Correct Ans C. prevent sedimentation
D. increasse sedimentation rate

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Q: 3 The filling of sterile medicinal products is done in


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A. Grade C area
✓ Correct Ans B. Grade A area
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C. Grade D area
D. none

Section: Mock test no 5 Question Type: Multiple Choice (Radiobutton) QID: 281
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Q: 4 Which one is a supplementary drug of first line antitubercular drugs


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✓ Correct Ans A. Streptomycin


B. Isoniazid
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C. Pyrazinamide
D. Ciprofloxacin

Section: Mock test 4 Question Type: Multiple Choice (Radiobutton) QID: 258

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Q: 5 As per IP, Total solids content in WFI is NMT

A. 15 ppm
✓ Correct Ans B. 10 ppm
C. 5 ppm
D. 20 ppm

Section: Mock test no 5 Question Type: Multiple Choice (Radiobutton) QID: 301

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Q: 6 The efficiency of HEPA filter is:

✓ Correct Ans A. remove at least 99.97% of airborne particles 0.3 micrometers (µm) in diameter.
B. remove at least 100% of airborne particles 0.3 micrometers (µm) in diameter
C. remove at least 99.97% of airborne particles 2 micrometers (µm) in diameter.
D. remove at least 97.99% of airborne particles 0.3 micrometers (µm) in diameter.

Explanation
to ensure 100 class, HEPA filter needed for air cleaning & efficiency of HEPA filter is checked in every six month
by (i) bubble point & (ii) DOP test

Section: Mock test no 5 Question Type: Multiple Choice (Radiobutton) QID: 283

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Q: 7 Class 10,000 is

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A. Particle count not to exceed a total of 10,000 particles per cubic foot of a size 5µ and larger
B. Particle count not to exceed a total of 10,000 particles per cubic foot of a size 0.5µ and smaller
C. Particle count not to exceed a total of 100,000 particles per cubic foot of a size 0.5µ and larger

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✓ Correct Ans D. Particle count not to exceed a total of 10,000 particles per cubic foot of a size 0.5µ and larger

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Q: 8 The volume of injection thorugh IM route is


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A. <2 ml
B. 0.1 ml
✓ Correct Ans C. 2-5 ml
D. >5 ml
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Section: Mock test no 5 Question Type: Multiple Choice (Radiobutton) QID: 298

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Q: 9 Pyrogens can NOT be destroyed using following technique

A. Dry heat temperature of 250C for 45 min.


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✓ Correct Ans B. Autoclaving cycle


C. Heating with strong alkali or oxidising solutions
D. None of the above
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Explanation
Pyrogen can destroy by heating at 650 ºC for 1 min, 250 ºC for 45 mints & 180 ºC for 4 hrs.
or heating with strong acid or alkali. These methods are used generally to sterile glassware & equipments.
removal of pyrogen from solution by (i) adsorption (ii) ultrafiltration based on Mw & (iii) heating carefully with
alkali/acid

Section: Mock test no 5 Question Type: Multiple Choice (Radiobutton) QID: 291

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Q: 10 coulter counter is used to determine

A. SA
✓ Correct Ans B. size of particles
C. density
D. flow property

Section: Mock test no 5 Question Type: Multiple Choice (Radiobutton) QID: 304

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Q: 11 pH of freshly prepared WFI is

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A. 2-5
✓ Correct Ans B. 5-7
C. 8-10

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D. > 10

Section: Mock test no 5 Question Type: Multiple Choice (Radiobutton) QID: 299

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Q: 12 Choose INCORRECT statement about emulsion

✓ Correct Ans
A. thermodynamically unstable preparation
B. stable preparation
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C. biphasic system
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D. both a & d

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Q: 13 example of w/o emulsion is

A. Rubber latex
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B. Egg yolk
C. vanishing creams
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✓ Correct Ans D. cold creams

Section: Mock test 4 Question Type: Multiple Choice (Radiobutton) QID: 243
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Q: 14 brownain movement occurs when particle size to a level of

A. 2 - 5 µm
B. 0.002-0.005 nm
C. 0.25-25 µm
✓ Correct Ans D. both a & b

Section: Mock test 4 Question Type: Multiple Choice (Radiobutton) QID: 263

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Q: 15 Microemulsions contain globules of the size about

A. 10 micrometer
B. 1 micrometer
✓ Correct Ans C. 0.1 micrometer
D. 0.01 micrometer
E. 100 micrometer

Section: Mock test 4 Question Type: Multiple Choice (Radiobutton) QID: 237

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Q: 16 Sulfur is used as a:

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A. surface coating material of glass containers
B. Additive in manufacturing of leaching proof plastic containers
✓ Correct Ans C. Vulcanising agent (curing agent) in rubber closures

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D. None of the above

Section: Mock test no 5 Question Type: Multiple Choice (Radiobutton) QID: 279

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Q: 17 Match correctly

Your Ans
A. multiple emulsion
B. Oil in water emulsion
Select
C Correct Ans W/O/W OR W/O/W

Your Ans C. water in oil emulsion


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Your Ans D. identification of emulsion
Section: Mock test 4 Question Type: Matching QID: 270
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Q: 18 The scattering of light by coarse and colloidal dispersed systems is known as?

A. Contrast matching
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B. DLVO theory
C. Creaming
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✓ Correct Ans D. Tyndall effect

Section: Mock test 4 Question Type: Multiple Choice (Radiobutton) QID: 247
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Q: 19 Which of the following is not a mechanism for the separation of a physically unstable suspension of magnesium
hydroxide in water?

✓ Correct Ans A. Hydrolysis


B. Aggregation
C. Flocculation
D. Ostwald ripening
Section: Mock test 4 Question Type: Multiple Choice (Radiobutton) QID: 248

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Q: 20 Which type of emulsion formed with tweens

A. W/O
✓ Correct Ans B. 0/W

C. CLEAR
D. UNSTABLE

Section: Mock test 4 Question Type: Multiple Choice (Radiobutton) QID: 239

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Q: 21 Which one disease has been declared as a notifiable by the govt of India

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A. TubercuLosis
B. Dengu
C. AIDS

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✓ Correct Ans D. All of the above

Section: Mock test 4 Question Type: Multiple Choice (Radiobutton) QID: 255

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Q: 22 Which of the following is NOT the principle problem areas exists in plastic containers:

A. leaching
B. permeation
C
✓ Correct Ans C. hardness
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D. sorption

Section: Mock test no 5 Question Type: Multiple Choice (Radiobutton) QID: 277
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Q: 23 Match the followings

A. sediment is easy to
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redisperse Select Correct Ans flocculated suspension


Your Ans B. sediment can not/difficult
to redisperse
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Your Ans C. particles settle


independently & separately
Your Ans D. particles settle as a flocs
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Section: Mock test 4 Question Type: Matching QID: 267

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Q: 24 Which type of suspension have relatively greater bioavailability

A. flocculated
✓ Correct Ans B. deflocculated
C. sedimanted
D. none

Section: Mock test 4 Question Type: Multiple Choice (Radiobutton) QID: 262

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Q: 25 Sedimentation volume of ideal suspension should be

A. less than one


B. more than one
✓ Correct Ans C. equal to one
D. zero

Section: Mock test 4 Question Type: Multiple Choice (Radiobutton) QID: 253

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Q: 26 Endotoxin is

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A. High molecular weight lipopolysaccharide
B. Secreted from cell wall of gram +ve bacteria
✓ Correct Ans C. Only A

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D. Both A and B

Explanation

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Endotoxin are High Mw Lipopolysaccharide, secreted by gram nagetive bacteria. gram +ve bacteria secretes
peptidoglacan & fungi secretes beta-glucans

Section: Mock test no 5 Question Type: Multiple Choice (Radiobutton)


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Q: 27 Rate of sedimentation of particles in suspension is expressed by


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A. Bankrot's rule
✓ Correct Ans B. stockes law
C. DLVO theory
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D. none

Section: Mock test 4 Question Type: Multiple Choice (Radiobutton) QID: 264
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Q: 28 Which of the following coating is used to lubricate vial rubber closures, syringe rubber plungers:
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A. teflon
✓ Correct Ans B. silicon
C. flurotec
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D. all of these

Section: Mock test no 5 Question Type: Multiple Choice (Radiobutton) QID: 278

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Q: 29 In practice, an ideal suspension should have partcles

A. non disperible
✓ Correct Ans B. redispersible
C. forms cake
D. should settle down
Section: Mock test 4 Question Type: Multiple Choice (Radiobutton) QID: 254

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Q: 30 andreason pippet is used to determine

✓ Correct Ans A. surface area of particles


B. size determination
C. density of powders
D. flow property

Section: Mock test no 5 Question Type: Multiple Choice (Radiobutton) QID: 303

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Q: 31 Propertion of solids in concentrate suspension & dilute suspension is respectively

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A. 2-10 %w/v; upto 50 %w/v
✓ Correct Ans B. upto 50 % w/v; 2 -10 % w/v
C. 2 % w/v; 70 % w/v

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D. None

Section: Mock test 4 Question Type: Multiple Choice (Radiobutton) QID: 256

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Q: 32 match correctly

Your Ans
A. suspension
B. fine emulsionappearance
Select
C Correct Ans 0.5-5 um

Your Ans C. Fine emulsion


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Your Ans D. microemulsion
appearance

Section: Mock test 4 Question Type: Matching QID: 269


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Q: 33 1 µm, 1 nm & 1 A° is equal to respectively


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✓ Correct Ans A. 10-6, 10-9, 10-10


B. 10-6,10-10, 10-9
C. 10-10, 10-9, 10-6
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D. 10-10, 10-6, 10-6

Section: Mock test no 5 Question Type: Multiple Choice (Radiobutton) QID: 302
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Q: 34 According to Stoke's law, which of the following minimizes particle sedimentation rate and thus enhances the stability
of a suspension

A. ncreasing particle size and decreasing viscosity of the liquid


✓ Correct Ans B. Decreasing particle size and increasing viscosity of the liquid
C. Decreasing particle size and decreasing viscosity of the liquid
D. Increasing particle size and increasing viscosity of the liquid

Section: Mock test no 5 Question Type: Multiple Choice (Radiobutton) QID: 289

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Q: 35

Choose correct answer: Sterilization Method vs Biological Indicators

A. A-ii, B-iv, C-iii, D-i


B. A-iii, B-ii, C-i, D-iii

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C. A-iv, B-ii, C-i, D-iii
✓ Correct Ans D. A-iii, B-i, C-iv D-ii

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Section: Mock test no 5 Question Type: Multiple Choice (Radiobutton) QID: 286

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Q: 36 which one of the following emulsifierslollipop is used to stabilize the emulsion of W/O type

✓ Correct Ans A. Span


B. Tween
C
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C. Acacia
D. Tragacanth

Section: Mock test 4 Question Type: Multiple Choice (Radiobutton) QID: 246
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Q: 37 pycnometer is used to determine

A. SA
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B. size
✓ Correct Ans C. density
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D. flow property

Section: Mock test no 5 Question Type: Multiple Choice (Radiobutton) QID: 305
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Q: 38 Sedimentation volume (F) of suspension is expressed by (Vu=Ultimate volume of sediment; Vo=Original volume of
sediment)

✓ Correct Ans A. Vu/Vo


B. Vo/Vu
C. Vu × Vo
D. (Vo/Vu) ×100

Section: Mock test 4 Question Type: Multiple Choice (Radiobutton) QID: 265

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Q: 39 According to IP, the preparation passess the Rabbit Pyrogen test if:

A. The group of three rabbits does not exceed 0.6°C


B. The group of three rabbits does not exceed 1.4°C and if the response of individual rabbit is less than 0.3°C
C. The group of three rabbits does not exceed 1.4°C and if the response of individual rabbit is less than 0.6°C
✓ Correct Ans D. the group of six rabbits does not exceed 1.4°C and if the response of individual rabbit is less than 0.6°C

Section: Mock test no 5 Question Type: Multiple Choice (Radiobutton) QID: 287

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Q: 40 Match correctly

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A. Wet gum method Select Correct Ans preparation of emulsion
Your Ans B. levigation
Your Ans C. trituration

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Your Ans D. pulverisation

Section: Mock test 4 Question Type: Matching QID: 271

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Q: 41 Type II glass is surface treated using

A. Silicon dioxide
B. Sulfur
C
✓ Correct Ans C. Sulfur Dioxide
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D. soda-lime

Explanation
type II glass is treated with sulphure dioxide to dealkalize the interior surface of container.
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Section: Mock test no 5 Question Type: Multiple Choice (Radiobutton) QID: 292

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Q: 42 Which of the following is FALSE statement

A. Parenterals has 100% bioavailability


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B. Parenterals are sterile and pyrogen free


C. Parenterals cause pain and discomfort
✓ Correct Ans D. Only aqueous formulations can be given parenterally
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Section: Mock test no 5 Question Type: Multiple Choice (Radiobutton) QID: 297

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Q: 43 Which of the following statement is true?

A. n an o/w/o emulsion, water is the external phase


B. In an o/w emulsion, water is the internal phase
✓ Correct Ans C. In an o/w/o emulsion, oil is the external phase
D. In a w/o emulsion, oil is the internal phase
Section: Mock test 4 Question Type: Multiple Choice (Radiobutton) QID: 250

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Q: 44 Which of the following statement is FALSE:

A. Powdered glass test is to test the leaching potential of internal structure of glass
✓ Correct Ans B. Water attack test is not for borosilicate glass
C. Powdered glass test is to estimate the amount of alkali leached from powdered glass
D. Water attack test is for soda-lime glass

Section: Mock test no 5 Question Type: Multiple Choice (Radiobutton) QID: 294

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Q: 45 Emulsion containing more than two phases are called as

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A. Mixed emulsion
✓ Correct Ans B. Multiple emulsion
C. Complex emulsion

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D. none of the above

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Q: 46 Lyophilisation is used for

✓ Correct Ans A. Preparation of dry powder


B. Formulation of sterile liquids
C
C. Increase solubilisation of drug
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D. None of the above

Section: Mock test no 5 Question Type: Multiple Choice (Radiobutton) QID: 288

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Q: 47 DOP used in validation of HEPA filter is

A. Dioctylpyruvate
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✓ Correct Ans B. Dioctylpthalate


C. Dioctahedralpthaladehyde
D. DioctanePthalazine
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Section: Mock test no 5 Question Type: Multiple Choice (Radiobutton) QID: 284

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Q: 48 Which one antitubercular drug is safe in the pregnancy

A. Capreomycin
B. Isoniazid
C. Pyrizinamide
✓ Correct Ans D. Ethambutol

Section: Mock test 4 Question Type: Multiple Choice (Radiobutton) QID: 259

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Q: 49 Brownian movement

A. Brownian movement may be exhibited by particle As large about 5 micrometre


B. Brownian movement works against the gravitational force
C. Particles are in continuous random motion
✓ Correct Ans D. all of the above

Section: Mock test 4 Question Type: Multiple Choice (Radiobutton) QID: 273

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Q: 50 Match correctly

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A. Kraft point Select Correct Ans temp. at which the solubility if surfactant is equal to the CMC
Your Ans B. Stock law
Your Ans C. Bancroft law

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Your Ans D. fick first law
Section: Mock test 4 Question Type: Matching QID: 272

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Q: 51 An emulsion is a system of two ..............liquid phases, one of which is dispersed as fine globules throughout the other.

A. miscible
B. polar
C
C. non-polar
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✓ Correct Ans D. Immiscible

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Q: 52 Emulsion have self life compare to other dosage form tablet & capsule

✓ Correct Ans A. short shelf life


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B. Large shelf life


C. No shelf life
D. None of these
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Section: Mock test 4 Question Type: Multiple Choice (Radiobutton) QID: 235

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Q: 53 Which of the following emulsion phenomena is usually reversible?

A. Breaking
✓ Correct Ans B. Creaming
C. Cracking
D. MOs contaminations
Section: Mock test 4 Question Type: Multiple Choice (Radiobutton) QID: 249

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Q: 54 match correctly

A. molecular dispersion Select Correct Ans less than 1 nm


Your Ans B. colloidal dispersion
Your Ans C. the coarse dispersion
Your Ans D. microemulsion

Section: Mock test 4 Question Type: Matching QID: 268

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Q: 55 Creaming Movement in O/W normal

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A. Downward
✓ Correct Ans B. Upward
C. Up first and down then

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D. Down first and OK then

Section: Mock test 4 Question Type: Multiple Choice (Radiobutton) QID: 245

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Q: 56 Powedered glass test challenges the leaching potential of:

A. Exterior structure of glass


B. Plastic containers
C
✓ Correct Ans C. Interior structure of glass
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D. Intact surface of glass

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Q: 57 Emulsion is prepared by which method

A. Wet gum method


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B. Dry gum method


C. Bottle method
D. homogenizers
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✓ Correct Ans E. All of these

Section: Mock test 4 Question Type: Multiple Choice (Radiobutton) QID: 274
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Q: 58 Vulcunisation of rubber is done by using

A. Silicone
B. Sulfuric acid
✓ Correct Ans C. Sulfur
D. Phosphorus

Section: Mock test no 5 Question Type: Multiple Choice (Radiobutton) QID: 295

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Q: 59 Which drug causes Orange red coloration of urine

✓ Correct Ans A. Rifampicin


B. rifabutin

C. Clofazimine
D. Dapsone

Section: Mock test 4 Question Type: Multiple Choice (Radiobutton) QID: 260

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Q: 60 Which one Is not a first line antitubercular drug

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A. Isoniazid
✓ Correct Ans B. Rifabutin
C. Rifampicin

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D. Pyrazinamide
E. Ethambutol

Section: Mock test 4 Question Type: Multiple Choice (Radiobutton) QID: 257

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Q: 61 Creaming is a process of

A. Difficult to predict
C
✓ Correct Ans B. Reversible
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C. Irreversible
D. Both A and B

Section: Mock test 4 Question Type: Multiple Choice (Radiobutton) QID: 236
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Q: 62 Which of the following is False


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A. Type I glass is used for all preparations


✓ Correct Ans B. Type III glass has more leaching property than Type I and II
C. Type II is not used for alkaline preparation
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D. Only A and B

Section: Mock test no 5 Question Type: Multiple Choice (Radiobutton) QID: 293
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Q: 63 Terminal sterilisation is

A. A process whereby a product is sterilized before filling in container


✓ Correct Ans B. A process whereby a product is sterilized in its final container or packaging
C. A process whereby raw materials are sterilised before formulation
D. A process whereby only API's are sterilised

Section: Mock test no 5 Question Type: Multiple Choice (Radiobutton) QID: 300

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Q: 64 vanishing creams is a type of emulsion

✓ Correct Ans A. O/W


B. W/O

C. BOTH
D. NONE OF THERE

Section: Mock test 4 Question Type: Multiple Choice (Radiobutton) QID: 244

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Q: 65 Which one of the following is the NOT a sterile formulation

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A. IV infusions
B. Ophthalmic preparations
C. infusion

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D. powders for injections
✓ Correct Ans E. lotion

Section: Mock test no 5 Question Type: Multiple Choice (Radiobutton) QID: 296

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Q: 66 C
Phase inversion of emulsion can be obtained by which method

A. Changing the chemical nature of emulsifier


B. Altering the phase volume ratio
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✓ Correct Ans C. both a & b
D. none

Section: Mock test 4 Question Type: Multiple Choice (Radiobutton) QID: 266
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Q: 67 high angle of repose indicates


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A. good flow property


✓ Correct Ans B. poor flow property
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Q: 68 Which type of suspension shows high rate of sedimentation

✓ Correct Ans A. flocculated


B. deflocculated
C. both
D. none
Section: Mock test 4 Question Type: Multiple Choice (Radiobutton) QID: 261

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Q: 69 Tuberculin Skin Test is performed to determine the presence of TB infection. The procedure involves a Mantoux test.
An injection of tuberculin into the forearm which is read 48-72 hours later, is given by which route

✓ Correct Ans A. Intradermal


B. s.c.
C. IM
D. IV

Section: Mock test no 5 Question Type: Multiple Choice (Radiobutton) QID: 275

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Q: 70 Stockes law is related to

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A. syrup
✓ Correct Ans B. suspension

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C. solution
D. none of these

Section: Mock test 4 Question Type: Multiple Choice (Radiobutton) QID: 252

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