A 68-year-Old woman with rheumatoid arthritis, who has been taking

nonsteroidal anti-

inflammatorY drugs (NSAIDS) for the past 10 years comp1atIS of burning epsthC

pain that is relieved by antacids, but worsened with food. Her doctor d
onunues *e

nsaids and starts her on cimetidifle Which of the following is truc regatthng
Ûie

pharmaCO10gi blockade of histamine H2 receptors in the pstric mucosa’

A. It Inhibits both gastrifl and acetylChO1iflmedu1t secretion of acìt

B. It inhibits gastrininduc but not mealstimulated secretion of acid

C. It has no effect on either gastrininduced or mea1.StimUlat sectetiOfl of

acid

D. It prevents activation of adenyl cyclase

E.It causeS an increase in potassium t1’