Professional Documents
Culture Documents
Aging, Sarcopenia1 - Fall 2017 PDF
Aging, Sarcopenia1 - Fall 2017 PDF
Aging, Sarcopenia1 - Fall 2017 PDF
Sarcopenia, and
Sarcopenic Obesity
Normal age-related changes
in body composition
• Fat mass increases from birth, peaks around 60-75 y
• Differences in adipose tissue distribution over lifespan
• Visceral fat and intramuscular fat tend to increase
• Subcutaneous does not (or, in fact, decreases)
• Fat infiltration into muscle is associated with lower
muscle strength
Defining Sarcopenia
(a continuously evolving definition…)
Sarcopenia
Normal
A muscle mass
index 2 or
more SD
Mean
below the sex-
- 2 SD
specific mean
Appendicular Skeletal Muscle (kg/m2) for young,
Muscle Mass Index (MMI) (kg/m2) healthy adult