UREUM REDUCTION RATIO DAN ESTIMATED GLOMERULAR FILTRATION

RATE IN PATIENT OUTGOING HAEMODIAYSIS

Silaban EMH1, ,Hariman H1
1
Postgraduate Program in Clinical Pathology Specialization, University of North Sumatra
2
Department of Clinical Pathology, Faculty of Medicine, University of North Sumatra
3
Department of Internal Medicine, Faculty of Medicine, University of North Sumatra

ABSTRACT
Background
Hemodialysis is the most frequent kidney replacement therapy in patients with stage V CKD (eGFR <15ml
/ minute / 1.73m2). Hemodialysis aims to remove excessive toxins or urea in the body, find adequate
hemodialysis, then need to know the value of urea reduction ratio (URR).
Aim
To determine the correlation of URR and eGFR in patients with regular hemodialysis.
Method
This study was conducted on stage V CKD patients who received regular HD with a total of 50 patients.
Urea examination is done before and after 30 minutes after HD is done. Ureum is examined using Architec
plus 4100 devices. The URR value is calculated with the pre HD ureum formula - Ureum post HD and
divided by pre HD ureum. The eGFR value is calculated using the CKD-EPI formula.
Results and Discussion
A total of 50 subjects participated in the study ,30 men (60%), 20 woman (40%). average value of the URR
was obtained (72.23 ± 7.9) and average value of eGFR (3.9 ± 1.76). there was no correlation between URR
and eGFR values in patients undergoing regular HD (p = 0.973).
Conclusion
No correlation between URR values and eGFR in patients undergoing regular HD.
Keyword: URR, eGFR, hemodialysis