DRUGS

NURSING
DRUG SPECIFIC MECHANISM OF ADVERSE EFFECT
INDICATION CONRAINDICATION RESPONSIBILITIES
ORDERED ACTION ACTION
 headache,  Assess for Renal
Ketoroloac Anti-pyretic Anti-inflammatory and Short-term  Contraindicated  dizziness, impairment,Impaired
NSAID analgesic management of with significant  somnolence, hearing,allergies,
40mg IV q6x2 activity;inhibits pain (up to 5 renal impairment  insomnia hepatic
doses prostaglandins and days)  fatigue,
leukotriene synthesis  Aspirin allergy  dizziness  Assess Skin color and
 tinnitus, lesions,orientation,
 Recent GI bleed or  ophthalmologic reflexes,peripheral
perforation effects sensation,clotting
times,
 Use cautiously with CBC,adventitious
impaired hearing sounds

 Allergies  Be aware that patient

may be at risk for CV
 Hepatic conditions events, GI
bleeding,renal toxicity,
monitor accordingly.

 Keep emergency
equipment readily
available at time of
initial dose, in case of
 severe hypersensitivity
reaction.

 Protect drug vials from

light.

 Administer every 6 hrs

to maintain serum
levels and control
pain.
 DRUG SPECIFIC MECHANISM OF CONRAINDICAT ADVERSE NURSING
INDICATION
ORDERED ACTION ACTION ION EFFECT RESPONSIBILITIES

Omeprazole Proton Pump Gastric acid pump Indicated for: Contraindicated  CNS :  Take the drug before meals.
Inhibitor inhibitor with Headache,  Report severe
40mg IV PTOR suppresses gastric  Short-term hypersensitivity to dizziness,asthen headache,worsening of
acid secretion treatment of omeprazole or its ia, vertigo, symptoms, fever, chills.K:
active duodenal components; Use insomnia,apathy  Swallow the capsules
ulcer; cautiously with , whole; do not chew, open,
pregnancy,lactatio anxiety,paresthe or crush them.
 First-line n sias, dream
therapy in abnormalities
treatment of
heartburn or  Dermatologic :
symptoms of Rash,inflammati
gastroesophagea on,
l reflux disease urticaria,pruritu
(GERD); s, alopecia, dry
skin
 Short-term
treatment of
active benign  GI :
gastric ulcer; y Diarrhea,
GERD, severe abdominal pain,
erosive nausea,
esophagitis, vomiting,constip
poorly ation, dry
responsive mouth,tongue
symptomatic atrophy
 GERD;

 Long-term
therapy:  Respiratory :
URI
Treatment of symptoms,cough
pathologichyper , epistaxis
secretory
conditions(Zollinger-  Other : Cancer
Ellison syndrome, in pre clinical
multiple adenomas, studies,back
systemic pain, fever
mastocytosis);

 Eradication of
H. pylori with
amoxicillin or
metronidazole
and
clarithromycin;
 DRUG SPECIFIC MECHANISM INDICATION CONRAINDICATION ADVERSE EFFECT NURSING
ORDERED ACTION OF ACTION RESPONSIBILITIES

Cefuroxime Antibiotic Second-generation Pharyngitis,  Contraindicated in Body as a Whole:  Determine history of

cephalosporin that tonsillitis,infections patients Thrombophlebitis (IV hyper sensitivity
750mg IV q8 inhibits cell-wall of the urinary and hypersensitive to site); pain, burning, reactions to
synthesis, lower respiratory drug.* cellulitis( IMsite); cephalosphorins,
promoting osmotic tracts, and skin and super infections, penicillins and history
instability; usually skin-structure  Use cautiously in positive Coombs' test. of allergies
bactericidal. infections caused patients particularly to drugs
by Streptococcus hypersensitive to GI: Diarrhea,nausea, before therapy
pneumoniae and S. penicillin because antibiotic- isinitiated.
pyogenes, of possibility of associatedcolitis.
Haemophillus cross-sensitivity  Report onselt of loose
influenzae, with other beta- Skin: stools
Staphylococcus lactam antibiotics. Rash, pruritus,
aureus, urticaria  Absorption of
Escherichia coli  Use with caution cefuroxime is enhanced
in breast-feeding Urogenital: Increased by food.
women and serum cretonne and
inpatients with BUN, decreased  Notify prescriber about
history of colitis or creatinine clearance rashes or super
renal sufficiency. infections
 NAME OF SPECIFIC MECHANISM OF INDICATION CONTRAINDICATION ADVERSE REACTION NSG.RESPONSIBILITIES
DRUG ACTION ACTION

Allergies  Flushing
Amlodipine Anti- Binds to To decrease the level  Monitor v/s esp. BP frequently
hypertensive dihydropyridine of blood pressure. Hypersensitivity to all  Increase angina  Observe for any adverse effect
50mgtab OD and cell skin therapy that may occur
membrane  hypotension  Avoid abrupt movement, the
receptor sites on drug may cause dizziness; to
 tachycardia
myocardial and prevent possible injury
vascular smooth  vasodilation  Administer as prescribed by the
muscles and physician only
 nausea and
inhibits ions across
vomiting
calcium channels.
 Headache

 lightheadedness

 dizziness

 anxiety
 NAME OF SPECIFIC MECHANISM OF INDICATION CONTRAINDICATION ADVERSE REACTION NSG.RESPONSIBILITIES
DRUG ACTION ACTION

Allergies  Headache
Ondansetron Anti-emetics Blocks the effects Prevents nausea and  Assess for nausea and vomiting
of serotonin at 5- vomiting Hypersensitivity  Dizziness abdominal distention, and bowel
40mg IV PTOR HT3- receptor sounds
sitesheadache; Liver impairment  Drowsiness  Check after giving medication
dizziness;  hold or not give this me if pt is
Abnormal surgery  Dry mouth
drowsiness; experiencing extrapyramidal
fatigue; weakness; Pregnancy  Fatigue effects (involuntary
constipation; movements, facial grimacing
 Body Weakness
diarrhea;(selective rigidity, shuffling
antagonist)  nausea and walk,trembling of hands
located in vagal vomiting
nerve
terminalsabdomin  lightheadedness
al pain; dry mouth;  Constipation
increased liver
enzymesand the  Diarrhea
chemoreceptor
trigger zone in the
CNSs.