Name : Amalia Savira

BP : 1410311032

DEMENTIA
Researchers have discovered a significant link between high use of anticholinergic
drugs including popular non-prescription sleep aids and the antihistamine Benadryl
(diphenhydramine) and increased risk of developing dementia and Alzheimer's disease in
older people.
Anticholinergics are a class of drug that blocks the action of the neurotransmitter
acetylcholine in the brain and body. This can lead to many side effects, including drowsiness,
constipation, retaining urine and dry mouth and eyes.
The researchers, led by Shelly Gray, a professor in the University of Washington
School of Pharmacy in Seattle, reported their findings in JAMA Internal Medicine in January
2015.
Prof. Gray says: "Older adults should be aware that many medications - including some
available without a prescription, such as over-the-counter sleep aids - have strong
anticholinergic effects." Prof. Gray urges people not to stop their therapy based on the
findings of this study – they should talk to their health care provider, and also tell them
about all their over-the-counter drug use. "Health care providers should regularly review
their older patients' drug regimens – including over-the-counter medications - to look for
chances to use fewer anticholinergic medications at lower doses.

Simple present ( fact ) : Red word