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Cost Savings From Emergency Contraceptive

Pills in Canada
JAMES TRUSSELL, PhD, ELLEN WIEBE, MD, TARA SHOCHET, MPH, AND
ÉDITH GUILBERT, MD, MSc

Objective: To estimate cost savings from emergency contra- and progestin and pills containing progestin only can
ceptive pills in Canada. be used for emergency contraception. Several brands of
Methods: We modeled cost savings when a single emer- combined oral contraceptives, one dedicated combina-
gency contraceptive treatment was provided after unpro-
tion product (Preven; Shire Canada, Inc., Oakville,
tected intercourse and when women were provided emer-
Ontario), and one dedicated progestin-only product
gency contraceptive pills in advance.
Results: Each dollar spent on a single treatment saved
(Plan B; Paladin Labs, Inc., Montreal) are available in
$1.19 –$2.35 (in Canadian currency), depending on the regi- Canada. All require a prescription and are available in
men and on assumptions about savings from costs avoided family planning clinics and through general practitio-
by preventing mistimed births. The dedicated products ners and gynecologists. Use of combined pills reduces
Preven (Shire Canada, Inc., Oakville, Ontario) and Plan B the risk of pregnancy by about 75%,2– 4 whereas use of
(Paladin Labs, Inc., Montreal) were cost-saving even under progestin-only pills reduces the risk by 89%.5
the least favorable assumption that mistimed births pre- Emergency contraception has the potential to reduce
vented today occur 2 years later. Each dollar spent on significantly the incidence of unintended pregnancy
advance provision of Preven saved $1.24 –$12.23, depending and the consequent need for abortion.6 In Canada, more
on the regular contraception method, on how consistently
than 100,000 women each year have abortions.7
emergency contraception was used when needed, and on
whether mistimed births were averted forever or simply
delayed. Plan B was almost always cost-saving, although less
so.
Methods
Conclusion: Emergency contraception was cost-saving We analyzed cost savings from two different emergency
whether provided when the emergency occurred or in ad- contraceptive protocols: (1) women seeking treatment
vance to be used as needed. More extensive use of emer-
after unprotected intercourse, and (2) providing women
gency contraception could save considerable medical costs
with emergency contraceptive pills during routine vis-
by reducing unintended pregnancies. (Obstet Gynecol 2001;
97:789 –93. © 2001 by The American College of Obstetri-
its to a clinician for later use if unprotected intercourse
cians and Gynecologists.) occurs.6 We considered only costs associated with med-
ical care and ignored social, psychologic, and other
nonmedical costs. Whether emergency contraceptive
Emergency contraceptive pills, which prevent preg- pills were cost-saving to the payer (the Ministry of
nancy after unprotected sexual intercourse, were found Health) depended on cost of treatment, probability of
to be cost-saving in the United States.1 In this study, we preventing an unintended pregnancy, and cost of such
estimate cost savings generated by use of emergency a pregnancy. Cost data were obtained from the British
contraception in Canada by comparing costs of treat- Columbia Ministry of Health. Each province adminis-
ment with savings generated by preventing unintended ters its medical insurance plan slightly differently, but
pregnancy. All costs are given in Canadian dollars. we chose to use one province’s data for convenience.
Ordinary oral contraceptives that contain estrogen The average cost of an unintended pregnancy is
$1289 (Table 1), which represents the weighted average
of the costs of ectopic pregnancy, induced abortion,
From the Office of Population Research, Princeton University, Prince- spontaneous abortion, and birth, with weights (1%,
ton, New Jersey, Department of Family Practice, University of British
Columbia, Vancouver, British Columbia, and Department of Obstetrics 51%, 12%, and 37%, respectively) equal to the probabil-
and Gynecology, Laval University, Ste-Foy, Quebec, Canada. ities of each outcome for unintended pregnancies.8

VOL. 97, NO. 5, PART 1, MAY 2001 0029-7844/01/$20.00 789


PII S0029-7844(01)01333-3
Table 1. Cost* of Unintended Pregnancy and Emergency used perfectly but nevertheless broke or slipped. In
Contraceptive Pills contrast, women who rely on other methods would use
Average cost of an unintended pregnancy, $1,288.61 emergency contraception only when they did not use
averted-birth model† their contraceptive or used it incorrectly. Only at such
Average cost of an unintended pregnancy, $734.79
times would they know that intercourse was unpro-
delayed-birth model‡
Average cost of a birth $2,381.39 tected. Therefore, we assumed that use of combined
Average cost of a spontaneous abortion $742.78 and progestin-only pills would prevent 74% and 89%,
Average cost of an ectopic pregnancy $1,580.46 respectively, of pregnancies conceived during typical
Average cost of an induced abortion $618.46 (perfect and imperfect) use of condoms and imperfect
Cost of Preven $5.00
use of other methods (Table 2). For all methods except
Cost of Plan B $15.95
Cost of physician visit $26.53 the sponge, typical-use and perfect-use probabilities
were taken from a literature review.11 The typical-use
* Costs are in Canadian dollars.

Assumes that an unintended (either unwanted or mistimed) birth, probability for the sponge was taken from results of a
if avoided today, will never occur later. clinical trial (Colin P, Creatsas G, Guerrero E, Guilbert

Assumes that an unwanted birth, if avoided today, will never E, Guimont J, Serfaty D. Multinational open phase II
occur later but that a mistimed birth, if avoided today, will occur 2
years later. study of the efficacy, safety and acceptability of the
Protectaid contraceptive sponge. Presented at the 55th
Annual Conference of the Society of Obstetricians and
Estimates in our base model, hereafter denoted the Gynecologists of Canada. June 1999, Ottawa, Ontario,
averted-birth model, overstate the medical costs of Canada). However, in this study the perfect-use prob-
unintended pregnancies because we assumed that ability (0.11) was estimated incorrectly and therefore
births, if prevented today, would not occur later. In fact, biased downward because all exposure was included in
only 30% of unintended births, if prevented, will not the denominator, not just exposure during correct and
occur later; the remainder are timing failures (births consistent use of the method. Therefore we arbitrarily
that occur sooner than intended).9 Therefore, we also set the perfect-use probability at 0.13. Given that
developed a delayed-birth model, assuming that women do not use their regular contraceptive perfectly,
women with timing failures would become pregnant they might not use emergency contraception after every
intentionally 2 years later and discounting costs beyond incidence of unprotected intercourse. Therefore, we
the current year to present value at an annual rate of modeled two scenarios, in which emergency contracep-
5%. In the delayed-birth model, the average cost of an tives are used after all and after three quarters of all
unintended birth decreased to $869 (⫽$2381 ⫺ [1.0 ⫺ unprotected acts of intercourse.
0.70/1.052]), and the average cost of an unintended
pregnancy consequently decreased to $735. The average
Results
cost of treating women after unprotected intercourse
was $31.53 for Preven ($26.53 for the office visit and In the averted-birth model, one use of Preven saves
$5.00 for the drug) and $42.48 for Plan B ($26.53 for the $2.35 in unintended pregnancy costs for every dollar
office visit and $15.95 for the drug). spent on the drug (Table 3), whereas Plan B saves $2.09
The cost of advance provision depends directly on per dollar spent. In the delayed-birth model, a single
the number of times women use emergency contracep- treatment with Preven or Plan B is still cost-saving. In
tion. We assumed that women using barrier methods, the averted-birth model, advance provision and consis-
spermicides, periodic abstinence, and withdrawal rou- tent use of Preven would produce annual savings from
tinely are provided three packs of either product.6 (We $2.90 among women who use the sponge to $12.23
ignored treatment among women using oral contracep- among parous women who use the cervical cap (Table
tives who miss pills.10) The cost per woman receiving 4) for each dollar spent on emergency contraception.
Preven would be $41.53 ($26.53 for the office visit and With less consistent use, savings would decrease by
$15.00 for the drug), and the cost per woman receiving 25%, but savings for each dollar spent would be at least
Plan B would be $74.38 ($26.53 for the office visit and $2.17. Advance provision of Plan B saves less because
$47.85 for the drug). For the diaphragm and the cervical the higher price of the drug outweighs its higher
cap, costs would be lower ($15.00 for Preven and $47.85 efficacy. Nevertheless, advance provision of Plan B is
for Plan B) because no extra office visit would be cost-saving.
required beyond the one to fit the device. In the delayed-birth model, annual savings per dollar
Women who rely on male or female condoms could spent on Preven (provided in advance) would range
use an emergency regimen whenever condoms were from $1.65 among women using the sponge to $6.97
used imperfectly (not used or used incorrectly) or were among parous users of the cervical cap, when the

790 Trussell et al Emergency Contraception in Canada Obstetrics & Gynecology


Table 2. Annual Probabilities of Pregnancy During Typical and Perfect Use and With Emergency Contraceptive Backup
Emergency contraceptive backup*

Method use Consistent use† Inconsistent use‡

Method Typical Perfect Preven Plan B Preven Plan B

Male condom 0.14 0.03 0.04 0.02 0.06 0.05


Female condom 0.21 0.05 0.05 0.02 0.09 0.07
Diaphragm 0.20 0.06 0.09 0.07 0.12 0.10
Cervical cap
Parous women 0.40 0.26 0.26 0.23 0.29 0.27
Nulliparous women 0.20 0.09 0.11 0.09 0.13 0.11
Sponge 0.23 0.13 0.14 0.12 0.16 0.15
Spermicides 0.26 0.06 0.10 0.07 0.14 0.12
Withdrawal 0.19 0.04 0.07 0.05 0.10 0.08
Periodic abstinence 0.25 0.09 0.12 0.09 0.15 0.13
* We assumed that for methods other than condoms, pregnancy rates during imperfect use would be reduced by E% if emergency contraceptive
pills are used consistently (where E ⫽ 74% for combined pills and E ⫽ 89% for progestin-only pills); therefore, the pregnancy rate during typical
use of a method combined with consistent use of emergency contraception would be Ppfp ⫹ (1 ⫺ E) ⫺ (ft ⫺ Ppfp), where ft and fp are contraceptive
failure rates during typical and perfect use, respectively, and Pp is the proportion of use that is perfect, here assumed conservatively to be 80%.
Estimates of ft and fp are drawn from the literature on contraceptive efficacy.11 When emergency contraceptive pills are used after only
three-quarters of all unprotected acts of intercourse, the pregnancy rate during typical use of a method would be Ppfp ⫹ (1.0 ⫺ 0.75 ⫺ E)(ft ⫺ Ppfp).
We ignored the distinction between annual probabilities of failure (ft and fp) and annual failure rates because the two are nearly identical. Consider
the following simple birth-interval model for women using spermicides. An annual probability of failure during typical use of 0.21 implies an
average monthly probability of failure of 0.0195 (⫽ 1.0 ⫺ [1.0 ⫺ 0.21]1/12). Assuming this probability is constant over time, the average waiting time
to conception while using spermicides is 51 months (⫽ 1/0.0195). Then ignoring ectopic pregnancies, spontaneous abortions, and stillbirths and
assuming that every other pregnancy ends in induced abortion, the waiting time to a conception leading to a live birth would be 106 months: 51
months to get pregnant the first time, three months’ gestation until the abortion, 1 month of postpartum nonsusceptibility after the abortion, and
51 months to get pregnant again. The entire interval from one birth to the next would be 117 months: 2 months of postpartum nonsusceptibility
after the birth (assuming minimal breastfeeding), 106 months of waiting time to the next live-birth conception, and 9 months for gestation. Hence
a birth occurs every 117 months or 9.75 years, so the birth rate per year is 0.103 (⫽ 1/9.75). Because there are two pregnancies for each birth, the
pregnancy rate per year is 0.206 (⫽ 2 ⫺ 0.103), a rate that is close to the annual probability of failure of 0.21. Differences are even smaller for more
effective methods.

Assumes use 100% of the time when needed.

Assumes use only 75% of the time when needed.

regimen is used consistently. Less consistent use would Discussion


still be cost-saving among users of all methods. Ad-
vance provision of Plan B is cost-saving whether the Emergency contraception reduces expenditures on
drug is used consistently or inconsistently, except medical care by preventing unintended pregnancies,
among women who rely on the male condom or the which are expensive. It is generally cost-saving whether
sponge. it is provided when the emergency occurs or in advance
to be used as needed. Several caveats are in order when
interpreting our results. We used data from the United
States on contraceptive failure, outcomes of unintended
Table 3. Costs* and Cost Savings for Single Use of pregnancies, and proportion of unintended births that
Emergency Contraceptive Pills
are unwanted because Canadian data were not avail-
Averted-birth Delayed-birth able. The proportion of unwanted among unintended
model† model‡
births might be lower in Canada because unwanted
Savings/ Savings/ births are a larger fraction of unintended births among
ECP regimen Cost Savings cost Savings cost
the poor and blacks,9 and Canada has proportionately
Preven $31.53 $74.10 $2.35 $42.25 $1.34 fewer women in these groups than does the United
Plan B $42.48 $88.79 $2.09 $50.63 $1.19
States. Contraceptive failure rates during typical use
ECP ⫽ emergency contraceptive pills.
might be lower in Canada for the same reason.12,13
* Costs are in Canadian dollars.

Assuming that an unintended (either unwanted or mistimed) birth, Moreover, our estimates of cost savings from emer-
if avoided today, will never occur later. gency contraceptive pills are likely to be understated for

Assuming that an unwanted birth, if avoided today, will never
occur later but that a mistimed birth, if avoided today, will occur 2 six reasons. First, in the scenario in which emergency
years later. contraception is provided only after unprotected inter-

VOL. 97, NO. 5, PART 1, MAY 2001 Trussell et al Emergency Contraception in Canada 791
Table 4. Costs* and Cost Savings for Advance Provision of Emergency Contraceptive Pills
Averted-birth model†—Preven Delayed-birth model‡—Preven

Inconsistent use of Inconsistent use of


Consistent use of ECPs§ ECPs¶ Consistent use of ECPs§ ECPs¶

Method Cost Savings Savings/cost Savings Savings/cost Savings Savings/cost Savings Savings/cost

Male condom $41.53 $133.75 $3.22 $100.31 $2.42 $76.27 $1.84 $57.20 $1.38
Female condom $41.53 $200.63 $4.83 $150.47 $3.62 $114.40 $2.75 $85.80 $2.07
Diaphragm $15.00 $145.22 $9.68 $108.91 $7.26 $82.81 $5.52 $62.10 $4.14
Cervical cap
Parous $15.00 $183.43 $12.23 $137.57 $9.17 $104.60 $6.97 $78.45 $5.23
Nulliparous $15.00 $122.29 $8.15 $91.72 $6.11 $69.73 $4.65 $52.30 $3.49
Sponge $41.53 $120.38 $2.90 $90.28 $2.17 $68.64 $1.65 $51.48 $1.24
Spermicides $41.53 $202.54 $4.88 $151.90 $3.66 $115.49 $2.78 $86.62 $2.09
Withdrawal $41.53 $150.95 $3.63 $113.21 $2.73 $86.07 $2.07 $64.56 $1.55
Periodic abstinence $41.53 $170.06 $4.09 $127.54 $3.07 $96.97 $2.33 $72.73 $1.75

Averted-birth model†—Plan B Delayed-birth model‡—Plan B

Male condom $74.38 $160.20 $2.15 $120.15 $1.62 $91.35 $1.23 $68.51 $0.92
Female condom $74.38 $240.30 $3.23 $180.23 $2.42 $137.02 $1.84 $102.77 $1.38
Diaphragm $47.85 $173.93 $3.63 $130.45 $2.73 $99.18 $2.07 $74.38 $1.55
Cervical cap
Parous $47.85 $219.70 $4.59 $164.78 $3.44 $125.28 $2.62 $93.96 $1.96
Nulliparous $47.85 $146.47 $3.06 $109.85 $2.30 $83.52 $1.75 $62.64 $1.31
Sponge $74.38 $144.18 $1.94 $108.14 $1.45 $82.21 $1.11 $61.55 $0.83
Spermicides $74.38 $242.59 $3.26 $181.94 $2.45 $138.33 $1.86 $103.75 $1.39
Withdrawal $74.38 $180.80 $2.43 $135.60 $1.82 $103.09 $1.39 $77.32 $1.04
Periodic abstinence $74.38 $203.68 $2.74 $152.76 $2.05 $116.14 $1.56 $87.11 $1.17
ECPs ⫽ emergency contraceptive pills.
* Costs are in Canadian dollars.

Assuming that an unintended (either unwanted or mistimed) birth, if avoided today, will never occur later.

Assuming that an unwanted birth, if avoided today, will never occur later but that a mistimed birth, if avoided today, will occur 2 years later.
§
Assuming ECPs are used 100% of the time when needed.

Assuming ECPs are used only 75% of the time when needed.

course, we assumed that an office visit is always re- Fourth, when we examined advance provision, we
quired. In fact, some clinicians prescribe by telephone, assumed in the worst-case scenario that emergency
especially for established patients, or delegate to a contraceptive pills would be used on only three quar-
nurse because a physical examination is not medically ters of occasions when they were needed. Women and
necessary. When an emergency regimen is prescribed in couples who consistently do not use a regular method
advance, women can renew their prescription by tele- of contraception might use emergency regimens far
phone as needed. more consistently. One might argue instead that a
Second, we assumed that women or providers would woman who knows she has a backup will become less
pay average wholesale prices for pills. In fact, many diligent with her regular method; however, if used as
providers receive discounts. For example, some pay ongoing methods, emergency regimens would be far
only $3.25 for an entire pack of Ovral (Wyeth-Ayerst less effective than most other contraceptives. During a
Canada, Inc., St-Laurent, Quebec) (enough for five year of typical use, a woman’s risk of pregnancy would
treatments), whereas we assumed they would provide be 20% with Plan B and would exceed 35% with Preven.
Preven, which costs $5.00 for a single treatment. One in two women have nausea and one in five women
Third, we assumed that treatment after unprotected vomit after using the combination regimen, and using it
intercourse prevented 74% (combined pills) or 89% repeatedly in one cycle or in several cycles in a row
(progestin-only pills) of pregnancies that would oth- would result in menstrual chaos. Those risks are likely
erwise occur. The true effectiveness of these regimens to dissuade women from frequent use and might en-
is probably higher because the observed number of hance regular contraceptive use. Making emergency
pregnancies is likely to be too high and the expected contraception more widely available does not increase
number of pregnancies is probably too low in efficacy risk-taking but reduces the incidence of unintended
studies.2– 4 pregnancy.14 Women who are the most diligent about

792 Trussell et al Emergency Contraception in Canada Obstetrics & Gynecology


ongoing contraceptive use are those most likely to seek tive pills: A simple proposal to reduce unintended pregnancies.
emergency treatment.15 Fam Plann Perspect 1992;24:269 –73.
7. Statistics Canada. Therapeutic abortions, 1995. Health Reports
Fifth, when we examined advance provision, we 1997;9(3):55.
assumed that each woman would use her emergency 8. Henshaw SK. Unintended pregnancy in the United States. Fam
regimen three times. Use of emergency contraception Plann Perspect 1998;30:24 –29, 46.
three or more times in a year is very uncommon,14 so 9. Abma JC, Chandra A, Mosher WD, Peterson LS, Piccinino LJ.
the average annual cost of advance provision is over- Fertility, family planning, and women’s health: New data from the
1995 National Survey of Family Growth. Vital Health Stat 1997;23:
stated. If each woman used only two packs of emer- 25.
gency contraceptive pills on average, then advance 10. Guillebaud J. When do you need to give emergency contraception
provision of Plan B would be cost-saving even under for missed pills? Fertil Control Rev 1995;4:18 –20.
the least favorable assumptions that mistimed births are 11. Trussell J. Contraceptive efficacy. In: Hatcher RA, Trussell J,
merely delayed for 2 years and that the regimen is used Stewart F, Cates W, Stewart GK, Kowal D, Guest F, eds. Contra-
ceptive technology. 17th rev ed. New York: Ardent Media, 1998;
only 75% of the time when needed. 779 – 844.
Sixth, we underestimated cost of births resulting from 12. Trussell J, Vaughan B. Contraceptive failure, method-related dis-
unintended pregnancy. We assumed that unintended continuation and resumption of use: Results from the 1995 Na-
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13. Fu H, Darroch JE, Haas T, Ranjit N. Contraceptive failure rates:
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be much longer; and the longer such births are post- Fam Plann Perspect 1999;31:56 – 63.
poned, the more likely it is that they will never occur. 14. Glasier A, Baird D. The effects of self-administering emergency
We incorrectly assumed that the cost of medical care for contraception. N Engl J Med 1998;339:1– 4.
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emergency contraception in Finland. Contraception 1997;55:153–7.
for all births.16 16. Brown SS, Eisenberg L, eds. The best intentions: Unintended
pregnancy and the well-being of children and families. Washing-
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E-mail: trussell@princeton.edu
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VOL. 97, NO. 5, PART 1, MAY 2001 Trussell et al Emergency Contraception in Canada 793

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