Collins 1

Jordan Collins

Dr. Guenzel

ENC 1102-0203

October 8, 2018

Digital Paper Trail

Questions:

What prescribe drugs at pain management facilities are the most addictive?

What is prescribed to prevent addiction, and how does it work?

What pharmaceutical advances are being made to prevent addiction?

What types of alternative medicine can take the place of prescription drugs to aid in pain
management?

Keywords:

 Addictive prescription drugs

 Pain management problems
 Opioids
 Pain management history
 Ways to manage pain
 Rate of addiction
 Alternative medicine
 Pain management

Sources:

Pain Management and Addiction [E-mail interview]. (n.d.). (Date TBD)

Drugs A-Z List - A on RxList. (n.d.). Retrieved September 19, 2018, from
https://www.rxlist.com/drugs/alpha_a.htm

Olson, K. A. (2015, May 19). History of Pain: The Treatment of Pain. Retrieved September 19,
2018, from https://www.practicalpainmanagement.com/treatments/pharmacological/history-
pain-treatment-pain?page=0,1

Collier, R. (2018, January 08). A short history of pain management. Retrieved September 19,
2018, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760261/
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Sabatowski, Rainer & Schäfer, Daniel & Kasper, Mario & Brunsch, H & Radbruch, Lukas.
(2004). Pain Treatment: A Historical Overview. Current pharmaceutical design. Retrieved
September 19, 2018.

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How Opioid Addiction Ocurrs (2018, February 16). Retrieved September 19, 2018, from
https://www.mayoclinic.org/diseases-conditions/prescription-drug-abuse/in-depth/how-
opioid-addiction-occurs/art-20360372

Inspirion Delivery Technologies Announces FDA Acceptance of MorphaBond^TM^ ER

morphine sulfate extended-release New Drug Application; Its Investigational Abuse-
Deterrent, Extended-Release Opioid. (2015). Biotech Week. Retrieved from
http://abusedeterrent.org/news/Inspirion-Delivery-Technologies-Announces-FDA-
Acceptance-of-MorphaBonde284a2-ER-morphine-sulfate-extended-release-New-Drug-
Application3b-Its-Investigational-Abuse-Deterrent-Extended-Release-Opioid-7c-PR-
Newswire.aspx#.W79bT2hKg2w

Collegium updates US FDA’s review of abuse-deterrent analgesic Xtampza ER. (2015). M2

Communications. Retrieved from
https://www.thefreelibrary.com/Collegium+updates+US+FDA%27s+review+of+abuse-
deterrent+analgesic...-a0431422855

Salwan, A. J., Hagemeier, N. E., & Harirforoosh, S. (2018). Abuse-Deterrent Opioid

Formulations: A Key Ingredient in the Recipe to Prevent Opioid Disasters? Clinical Drug
Investigation, 38(7), 573–577. Retrieved from
https://login.ezproxy.net.ucf.edu/login?auth=shibb&url=https://search.ebscohost.com/login.a
spx?direct=true&db=sph&AN=130360541&site=eds-live&scope=site

Pergolizzi, J. V., Jr., Raffa, R. B., Taylor, R., Jr., & Vacalis, S. (2018). Abuse-deterrent opioids:
an update on current approaches and considerations. CURRENT MEDICAL RESEARCH
AND OPINION, 34(4), 711–723. https://doi.org/10.1080/03007995.2017.1419171

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Embeda with abuse-deterrent properties. (2014). MPR Monthly Prescribing Reference, (12), 14.
Retrieved from
https://login.ezproxy.net.ucf.edu/login?auth=shibb&url=https://search.ebscohost.com/login.a
spx?direct=true&db=edsgao&AN=edsgcl.436983637&site=eds-live&scope=site

Tayebeh Rakhshani, Mahbobeh Firouzkouhi Moghaddam, Fariba Kadkhodaie, & Mostafa

Rashki. (2018). Methadone and Buprenorphine for the Treatment of Opiate
Addiction. Journal of Human, Environment, and Health Promotion, Vol 3, Iss 2, Pp 80-86
(2018), (2), 80. Retrieved from
https://login.ezproxy.net.ucf.edu/login?auth=shibb&url=https://search.ebscohost.com/login.a
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spx?direct=true&db=edsdoj&AN=edsdoj.4f7f626933a4a1a924746eefc9fb47d&site=eds-
live&scope=site

FDA Approves Abuse Deterrent Labeling for EMBEDA[R] (morphine sulfate and naltrexone
hydrochloride) Extended-Release (ER) Capsules CII. (2014). Business Wire. Retrieved from
https://login.ezproxy.net.ucf.edu/login?auth=shibb&url=https://search.ebscohost.com/login.a
spx?direct=true&db=edsggo&AN=edsgcl.411809497&site=eds-live&scope=site

Abuse-Resistant Prescription Painkiller Approved; Hysingla ER is only for chronic pain, and is
formulated to resist crushing, dissolving. (2014). Consumer Health News (English).
Retrieved from
https://login.ezproxy.net.ucf.edu/login?auth=shibb&url=https://search.ebscohost.com/login.a
spx?direct=true&db=edsgbe&AN=edsgcl.390928657&site=eds-live&scope=site

2018 Prescription Drug Abuse Statistics You Need To Know. (2018, September 10). Retrieved
October 8, 2018, from https://talbottcampus.com/prescription-drug-abuse-statistics/

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A New Abuse-Deterrent Opioid - Xtampza ER | The Medical Letter, Inc. (2016, June 20).
Retrieved October 8, 2018, from https://secure.medicalletter.org/w1497a

Chronic Pain: In Depth. (2018, September 12). Retrieved October 8, 2018, from
https://nccih.nih.gov/health/pain/chronic.htm

Coronado, R. A., & Bialosky, J. E. (2017, July 12). Manual physical therapy for chronic pain:
The complex whole is greater than the sum of its parts. Retrieved October 8, 2018, from
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498791/

Khazzoom, L. (n.d.). Alternative Treatments for Chronic Pain without Drugs - AARP The M...
Retrieved October 8, 2018, from https://www.aarp.org/health/alternative-medicine/info-11-
2008/drug_free_remedies_chronic_pain.html

National Institute on Drug Abuse. (2016, February 08). Abuse of Prescription (Rx) Drugs
Affects Young Adults Most. Retrieved October 8, 2018, from
https://www.drugabuse.gov/related-topics/trends-statistics/infographics/abuse-prescription-
rx-drugs-affects-young-adults-most

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Opioid Overdose. (2017, August 30). Retrieved October 8, 2018, from

https://www.cdc.gov/drugoverdose/data/prescribing.html

Pain Medications. (n.d.). Retrieved October 8, 2018, from https://www.webmd.com/pain-

management/guide/pain-relievers#1
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Physical Therapy for Chronic Pain Is Proven to Be Highly Effective. (n.d.). Retrieved October 8,
2018, from https://lasvegasrecovery.com/pain/chronic-pain-therapy/physical-therapy-for-
chronic-pain/

Sahai-Srivastava, S. (n.d.). Common Alternative Treatments for Chronic Pain. Retrieved October
8, 2018, from https://www.practicalpainmanagement.com/common-alternative-treatments-
chronic-pain

Taking pills for chronic pain? (2018, February 14). Retrieved October 8, 2018, from
https://www.mayoclinic.org/chronic-pain-medication-decisions/art-20360371

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Tennant, F. (2018, May 1). Medications for Chronic Pain. Retrieved October 8, 2018, from
https://www.practicalpainmanagement.com/patient/treatments/medications/medications-
chronic-pain

Herzberg, D. (2015, September 15). The Other Drug War: A History of Prescription Drug Abuse
in America. Retrieved October 8, 2018, from http://grantome.com/grant/NIH/G13-
LM012050-01

Torborg, L. (2017, January 14). Mayo Clinic Q and A: Alternative treatments for chronic pain.
Retrieved October 8, 2018, from https://newsnetwork.mayoclinic.org/discussion/mayo-
clinic-q-and-a-alternative-treatments-for-chronic-pain/