CHE1016 Fermentation Technology

L,T,P,J,C
Pre-Req: NIL 3, 0, 0,0,3
Module Topics L Hrs SLO
Introduction to fermentation processes
1 Basic Microbiology, Microbial growth - Batch, Continuous and fed batch 6 1,2
culture, Industrial applications.
Component parts of fermentation process
2 5 1,2
Biomass, enzymes, metabolites and biotransformation
Microbial Strain Management:
3 The isolation preservation and improvement of industrial microorganisms. 5 1
Isolation and storage methods
Media and industrial fermentations
4 Media formulation, energy, carbon and nitrogen sources micro nutrients, 4 1,2
oxygen requirements.
Preparation of Media & Innocula:
Preparation of media and air for pure culture fermentation. Media sterilization,
5 Batch and continuous sterilization processes, Sterilization of fibrous filters and 6 1
their design, Development of inocula: for processes involving yeast, bacterial,
fungi, Aseptic inoculation of plant fermentations.
Design of Fermenter
Basic functions of fermenter – Aeration and agitation – process requirements
6 and mechanical design aspects. Maintenance of aseptic conditions, foam 8 2,4
control in stirred and sparred tanks fermenters. Tower fermenter, Packed
tower, Air lift and rotating disc fermenters, Solid State fermentation.
Downstream Processing
Recovery and purification of fermentation products. Filtration and
7 6 1
centrifugation basic concepts Cell disruption for releasing intro cellular
products. Liquid – liquid extraction, chromatography and ultrafiltration.
Process technology for bulk products
8 Production of alcohols, organic acids, enzymes, and antibiotics – flow sheet 5 2
and process description of modern processes
Total Lecture Hours 45
Mode:
Flipped Class Room, [Lecture to be videotaped], Use of physical and computer models to lecture, Visit to Industry
and
study the thermal equipments, Min of 2 lectures by industry experts
Text Books
1. PF Stanbury , A. Whitaker and Steve Hall, Principles of Fermentation Technology, 3rd Edition,
Butterworth-Heinemann (2015)
Reference Books
1. Ashok Pandey, Christian Larroche, Carlos Ricardo Soccol, Advances in Fermentation Technology,
Asiatech Publishers Inc.,(2008)
2. A Rhodes and Pletcher. D.L Principles of Industrial Microbiology, Pergamon Press (1977) Modern
Technology of Bioprocessing Published by Engineers India Research Institute
Complied by Prof. Aruna Singh
Recommended by BoS on 04.03.16

Approved by Academic Council on 18.03.16