Personality Traits and Coffee Intake: Diogo R. Lara

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C H A P T E R

30
Personality Traits and Coffee Intake
Diogo R. Lara
Faculdade de Biociências, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS),
Porto Alegre, Rio Grande do Sul, Brazil

List of Abbreviations Although caffeine is unlikely to induce negative effects


ADHD  Attention deficit and hyperactivity disorder
when consumed in moderation, cessation of caffeine
BAS  Behavioral activation system intake often induces transient headache, drowsiness,
and fatigue.4 These withdrawal effects may contribute to
maintenance of a regular intake. In fact, individuals can
manipulate their caffeine doses to maximize their subjec-
30.1 INTRODUCTION tive benefits and avoid adverse and withdrawal effects.
The underlying mechanism of caffeine is the com-
Coffee is one of the most widely used and behav-
petitive antagonism at A1 and A2A adenosine recep-
iorally active foods.1 About 80% of the population
tors.5 Adenosine is a widespread neuromodulator that
voluntarily and routinely manipulate their mind phar-
interacts with other neurotransmitters at pre- and post-
macologically by ingesting coffee and other caffeinated
synaptic levels.6 Antagonism of A1 receptors increases
drinks. Coffee is a major source of caffeine, along with
dopamine D1 receptor affinity for dopamine and stimu-
soft drinks and tea, and their intake varies considerably
lates the release of neurotransmitters such as glutamate,
according to lifestyle, age, and culture. About half of caf-
dopamine, and acetylcholine.6 Also, antagonism of A2A
feine consumers ingest caffeine from multiple sources.1
receptors increases neurotransmission through dopa-
Since there is great individual variation in coffee con-
mine D2 receptors.6
sumption, it is expected the personality traits may be
Chronic administration of caffeine may result in par-
involved in the volume of intake and response to caf-
tial tolerance to a number of physiological, subjective,
feine (and possibly other ingredients of coffee). Another
and behavioral effects.4 There may not be a net benefit
possibility is that, by being regularly consumed, coffee
from caffeine consumption with regard to alertness and
may exert effects on personality itself and traits related
psychomotor performance because even brief abstinence
to psychiatric disorders. Most of these associations are
of dietary caffeine intake is accompanied by character-
putatively caused by the effects of caffeine on the central
istic withdrawal symptoms. Also, some of its putative
nervous system.
benefits on cognitive performance and mood may be
Caffeine produces behavioral and subjective effects
caused by the reversal of negative withdrawal effects.7
similar to typical psychomotor stimulant drugs (e.g.,
Personality traits are a major issue related with the use
amphetamine and cocaine),2 but the net effects are milder.
and abuse of and dependence on psychoactive drugs.8,9
Caffeine enhances feelings of well-being, energy, motiva-
Given the interaction between caffeine with neurotrans-
tion for work, and concentration; delays sleep; and pro-
mitters and caffeine’s effects on human behavior, it is
motes vigilance while performing psychomotor tasks.3
possible that its effects and intake pattern vary accord-
The effects of increased alertness and reduced fatigue
ing to personality traits. The main issues on this topic
induced by caffeine are more apparent in low-arousal sit-
addressed here are:
uations. The effects of caffeine are dose dependent, and as   

little as 30 mg of caffeine may affect mood and alertness, • A


 re there personality traits related to higher coffee
improve reaction times, and vigilance while performing intake? If present, do they remain after controlling
tasks.4 Higher doses can produce anxiety in susceptible for smoking, since smoking and coffee intake are
individuals and commonly induce insomnia when taken associated? How about other caffeinated drinks, such
at night. These are the main reasons to avoid coffee intake. as tea and colas?

Coffee in Health and Disease Prevention 275


http://dx.doi.org/10.1016/B978-0-12-409517-5.00030-9 © 2015 Elsevier Inc. All rights reserved.
276 30.  PERSONALITY TRAITS AND COFFEE INTAKE

• D o people with different personality profiles respond self-directedness (controlling for coffee consumption,
differently to coffee or caffeine? tea consumption, and smoking). This is a more favorable
• Can chronic use of coffee affect psychiatric disorders, and mature personality profile.
such as depression, perhaps by modulating The most robust link was the higher levels of harm
underlying personality traits? avoidance and novelty seeking and lower levels of self-
directedness and cooperativeness associated with cola
drink intake, using the other three substances as covari-
30.2  PERSONALITY TRAITS ates. This profile reflects a more unstable, pessimistic,
ASSOCIATED WITH COFFEE AND and immature personality. Controlling for coffee, tea,
CAFFEINE INTAKE and cola intake, smoking was associated mostly with
higher novelty seeking and lower self-directness. Alto-
One of the first studies to report an association gether, these findings point to a less adaptive personality
between caffeine consumption and personality traits profile among heavy cola drinkers and smokers, a puta-
showed that impulsive men, but not women, consumed tive association with more frequent mental disorders, a
almost twice the amount of caffeine as nonimpulsive neutral relationship with coffee, and a favorable person-
men (pooled data from many caffeine sources), without ality profile for heavy tea drinkers. Importantly, the nov-
controlling for smoking.10 This is a significant limitation elty seeking trait, commonly associated with drug abuse
since the association of coffee intake and cigarette smok- and dependence, was not different among those with
ing is common.11 Adan12 found higher levels of neuroti- high coffee intake. Another recent study showed that
cism were associated with heavier intake of cola drinks impulsivity, sensation seeking, behavioral activation
but found no difference in personality regarding coffee system (BAS)-drive, and BAS-fun were positively associ-
and tea intake among 537 subjects. Brice and Smith13 ated with caffeine intake but failed to analyze the differ-
also found no association between coffee consumption ent sources of caffeine and did not control for smoking.17
and extraversion or introversion among 243 individu- Altogether, these studies suggest that the personality
als. Another case–control study found that those with and caffeine measures (e.g., continuous or categorized
caffeine dependence (mostly from coffee and tea) have as high intake), the sample, the study design, and the
more sensation-seeking traits, but again, this study did sources of caffeine (combined or separate) can affect the
not control for tobacco use.14 A later study using the results.
Temperament and Character Inventory (first version) Caffeine induces anxiety at higher doses, typically
on 498 subjects and controlling for smoking reported >300 mg, and in susceptible individuals.18 However, the
higher novelty seeking behavior, but not other person- consumption of caffeine is poorly correlated with anxi-
ality traits, with heavy caffeine consumption (>200 mg/ ety or anxiety traits.15,19 Another trait associated with
day).15 However, this study evaluated caffeine intake caffeine intake relates to circadian rhythm. Subjects with
from a combination of multiple sources, so the specific an evening preference (i.e., evening types) drink more
associations of personality traits with different sources coffee and cola drinks.12 Interestingly, evening prefer-
of caffeine were not clear. ence is much more correlated with cola drink intake
The only study that distinguished between caffeine than with coffee intake.20 Penolazzi et al.17 reported that
sources and controlled for smoking was conducted morning-types consume more caffeine and coffee than
by Lara et al.16 This study evaluated the relationship evening-types in the morning and evening-types con-
between coffee, tea, and cola drink intake and personal- sume more at night than morning-types, suggesting that
ity traits measured with the full version of the revised caffeine is not necessarily used to counterbalance their
Temperament and Character Inventory in a large sample natural circadian cycles.
of the general population. The relationship of smok-
ing status with personality traits, controlling for these
caffeine sources, also was analyzed. The main finding 30.3  DIFFERENTIAL RESPONSE TO
of this study was the different associations of caffeine CAFFEINE ACCORDING TO
sources and smoking with personality traits. Controlling PERSONALITY TRAITS AND
for smoking, tea consumption, and cola drink intake, PSYCHIATRIC DISORDERS
coffee intake was only modestly related to tempera-
ment (reward dependence) and character differences One of the first studies showing personality dif-
(self-directedness and self-transcendence), and only for ferences in response to caffeine evaluated the trait of
the consumers of very large amounts, which accounted introversion/extraversion.21 This study showed that
for 3.3% of the sample (>10 cups/day). In contrast, tea time pressure and caffeine differentially affected the
consumption was linearly and significantly associated performance of introverts on verbal ability tests. With
with lower harm avoidance and higher persistence and 200 mg of caffeine and time pressure, the performance

I.   INTRODUCTORY AND GENERAL TEXT


30.4  Chronic Use of Coffee, Personality Traits, and Psychiatric Disorders 277
of introverts decreased substantially, whereas extroverts’ as low as 50–100 mg of caffeine suffice to induce mood
performance improved significantly. Ambiverts showed effects and in some individuals even 20–30 mg of caf-
no change with caffeine. Based on these results, Rev- feine cause noticeable effects.
elle et al.21 were the first to suggest that caffeine neither
increases or decreases average performance, but its effect
depends on individual differences in extroversion. These 30.4  CHRONIC USE OF COFFEE,
findings were replicated for impulsivity traits: caffeine PERSONALITY TRAITS, AND
increased the error detection rate of impulsive subjects PSYCHIATRIC DISORDERS
but decreased the error detection rate of less impulsive
subjects.22 Revelle et al.23 also suggested that the effect of There is a large body of data showing that individuals
caffeine may vary according to personality and time of with psychiatric disorders have different temperament
the day. According to their work cognitive performance and personality traits compared to healthy subjects.29
of impulsive subjects benefits particularly in the morn- One interesting possibility is that psychotropic treat-
ing but is hindered in the evening. The opposite pat- ment may produce its effect exactly by tackling these
tern seems to apply to nonimpulsive subjects. However, underlying traits. Thus, studies addressing how chronic
another study failed to replicate these findings, showing intake of coffee and caffeine relates to psychopathology
only a trend toward more caffeine-induced happiness may shed light on their effects on traits.
among extraverts.24 Some studies showed that caffeine intake is negatively
Smillie and Gökcen25 more recently evaluated the associated with the risk of depression. In one of the few
effect of 200 mg caffeine on working memory accord- cross-sectional population studies, Smith30 reported that
ing to introversion/extraversion. Their results showed consumption of caffeine, even at low doses, was associ-
that only extraverts benefitted from caffeine and in con- ated with a reduced risk of depression (odds ratio (OR),
ditions of high load for working memory (i.e., a three- 0.32 (95% confidence interval (CI)), 0.2–0.5 for 1–140 mg/
back task). These results have been interpreted in terms day; OR, 0.18 (95% CI), 0.1–0.3 for 141–260 mg/day; and
of dopamine function, which is a common neurochemi- OR, 0.12 (95% CI, 0.1–0.2) for >260 mg/day) compared to
cal denominator linking caffeine, working memory, and those with no caffeine intake. This study was conducted
extraversion. In this regard, the effect of caffeine may using a nonworking population, which may have higher
resemble the effect of other dopaminergic stimulants baseline levels of depression, probably facilitating
such as methylphenidate,26 improving a phasic mecha- the identification of this effect compared to a working
nism (dopamine reactivity) rather than a tonic mecha- population. A recent cross-sectional study confirmed
nism (dopamine activity). that coffee consumption was inversely associated with
The presence of specific anxiety disorders may influ- depressive symptoms (>2 vs 1 cup/day: OR, 0.57; P for
ence the perceived effects of caffeine. Earlier studies trend = 0.02) after adjusting for multiple factors.31 They
found patients with panic disorder and generalized found a similar association for tea consumption and for
anxiety disorder are more sensitive to the anxiogenic total caffeine intake from coffee and tea.
effects of high doses of caffeine (typically >400 mg). This Ruusunen et al.32 reported the first prospective but
pattern may be present to a lesser extent in depressed relatively small follow-up study examining the associa-
patients and patients with performance anxiety disorder, tions between the intake of coffee, tea, and caffeine and
but not generalized social anxiety disorder, as well as in depression. In a sample of 2232 middle-aged men with-
first-degree relatives of patients with panic disorder.27 out depression at baseline and followed for 17.5 years, a
Thus vulnerability to marked anxiogenic effects of caf- total of 4.9% of the noncoffee drinkers, 1.3% of the light
feine seems to be restricted to some individuals with at coffee drinkers, 2.6% of the moderate coffee drinkers, and
least a predisposition for specific anxiety disorders. 1.5% of the heavy coffee drinkers received a discharge
Considering preference for caffeine itself as a trait, diagnosis of depression during follow-up. After adjusting
those who prefer caffeine pills over placebo tend to for age, years under examination, socioeconomic status,
report stimulant and “positive” effects of caffeine on alcohol consumption, smoking, maximal oxygen uptake,
mood, whereas individuals that choose placebo tend to body mass index, and the energy-adjusted daily intakes
report aversive effects (increased anxiety and dysphoria) of folate and polyunsaturated fatty acids, heavy coffee
after caffeine intake.28 Similarly, caffeine only has sig- drinkers had a decreased risk (relative risk, 0.23; 95% CI,
nificant reinforcing effects on mood and psychomotor 0.06–0.83) for depression when compared with nondrink-
performance among caffeine consumers, but self-rated ers. Interestingly, they found no association with total caf-
alertness to caffeine increased among both caffeine con- feine intake, tea, or other caffeinated beverages.
sumers and nonconsumers. Interestingly, caffeine seems In 2011 a similar but larger cohort study addressed
to improve performance more in the nonconsumers the risk of depression in women according to coffee
while especially benefitting consumers’ mood. Doses intake.33 They showed that among 50,739 older women

I.   INTRODUCTORY AND GENERAL TEXT


278 30.  PERSONALITY TRAITS AND COFFEE INTAKE

free of significant depressive symptoms at baseline and intake and general cognitive ability and memory, but
followed for 20 years, risk of depression decreased in a most associations became nonsignificant after adjusting
dose-dependent manner with increasing consumption for intelligence quotient at age 11 and social class. How-
of caffeinated coffee. Multivariate relative risk of depres- ever, a strong positive association remained between
sion was 0.80 (95% CI, 0.68–0.95; P for trend = 0.02) for drinking ground coffee and cognitive performance on
women ingesting >550 mg caffeine/day versus those two tests, with no sex-related effects observed. Taken
with intake <100 mg caffeine/day. Interestingly, decaf- together, these cross-sectional studies suggest that caf-
feinated coffee was not associated with depression risk. feine produces benefits in cognitive functioning but that
Another important marker of mental disorder is suicid- those who consume more caffeine may have better cog-
ality. In three cohort studies34–36 there was strong inverse nitive performance, that is, higher caffeine intake may be
associations between coffee consumption and suicide, a behavioral marker of better cognition.
which is robustly associated with depression, although
a J-shaped relationship was found for coffee and suicide
risk in the Finnish cohort.36 Together, these results sug- 30.5 CONCLUSIONS
gest that intake of between 4 and 7 cups of regular coffee
(and caffeine) per day significantly reduces the risk of Some studies showed higher impulsivity, novelty
depression. No study evaluated changes in personality seeking, and sensation seeking among heavy caffeine
traits, however. The most likely candidate traits playing drinkers, but the relationship of coffee intake with per-
a role are volition/energy/self-directedness and emo- sonality traits is negligible when the results are con-
tional sensitivity to stress/harm avoidance/neuroti- trolled for smoking. However, the relationship of cola
cism. In summary, caffeine may have beneficial effects drinks with personality shows an association with more
on depressive or low-energy states and traits and may be impulsive and immature traits. A more adaptive profile
detrimental for some hypersensitive patients with panic was observed with higher tea consumption.
and/or performance anxiety disorder. The performance of extroverted and impulsive subjects
Caffeine often is used as a strategy to increase the abil- tends to benefit more from caffeine. Although coffee and
ity to sustain attention, particularly in situations of low caffeine may reverse low-energy states during the circa-
arousal or fatigue. Caffeine improves alertness and con- dian cycle, people seem to consume more coffee during
trol of executive functions in a dose–response manner, the more active phases of the day. Finally, chronic intake of
peaking at 200 mg. Encoding of new information also is caffeinated coffee seems to protect from depressive symp-
enhanced by 40 mg caffeine in volunteers with a mean toms, suicide, and cognitive decline, but the mechanisms
daily consumption of 138 mg. Thus caffeine may have of such benefit (e.g., effects on traits or states) need further
a therapeutic role in attention deficit and hyperactivity study. Since caffeine is easily available from coffee and
disorder (ADHD). The effects of caffeine on attention other sources, most individuals tend to naturally select
and performance have been studied in normal volun- doses that do not produce unfavorable subjective and
teers using several paradigms and protocols. somatic effects and may improve mood and performance.
Three cross-sectional population studies evaluated
the association between cognitive functioning and caf-
feine intake in real-life situations. Jarvis37 reported a 30.6  SUMMARY POINTS
dose–response trend of improved performance during
attention and memory tasks with higher levels of cof- • H igh impulsivity, novelty seeking, and sensation
fee consumption; a dose of 400 mg caffeine per day was seeking are traits associated with caffeine intake.
particularly beneficial. The associations were similar • When controlling for smoking, the association of
but weaker for tea consumption and more apparent in coffee intake with personality traits is negligible.
older than younger people. Smith38 showed that caffeine • Even controlling for smoking and coffee, intake of
consumption was significantly related to fewer cogni- cola drinks is related to impulsivity, novelty seeking,
tive failures (e.g., forgetting where things were, doing and immature personality.
the wrong thing, or failing to concentrate) in a working • The performance of extraverts responds more
population. Those who had low caffeine consumption favorably to caffeine than that of introverts.
had about twice the risk of self-reporting frequent/very • Caffeine may induce anxiety but the consumption of
frequent cognitive failures and accidents at work com- caffeine is poorly correlated with anxiety traits.
pared to those with higher caffeine intake. Finally, an • Caffeine reverses low-energy phases but is usually
elegant study evaluated the association of coffee and caf- ingested more during active phases of the day.
feine intake and cognitive decline, including intelligence • Coffee intake is negatively associated with the risk
quotient at age 11 as a covariate.39 The results showed of developing depression and committing suicide in
significant positive associations between total caffeine follow-up studies.

I.   INTRODUCTORY AND GENERAL TEXT


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I.   INTRODUCTORY AND GENERAL TEXT

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