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  • Second Professional MBBS Degree Examinations, February 2016: Q.P. Code: 205001 Reg. No.

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    1. The clinical history describes a 24-year-old man admitted with diarrhea for two days who is severely dehydrated and has rice water stool. The probable diagnosis is cholera caused by Vibrio cholerae. A stool sample should be collected in Cary-Blair transport medium and sent to the laboratory for analysis. Cholera's pathogenesis involves colonization of the small intestine by V. cholerae which produces an enterotoxin causing a massive outpouring of fluid into the intestine. Laboratory diagnosis of cholera involves culture, microscopy, and biochemical testing of the stool sample. Prophylaxis involves oral rehydration therapy.

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    1. The clinical history describes a 24-year-old man admitted with diarrhea for two days who is severely dehydrated and has rice water stool. The probable diagnosis is cholera caused by Vibrio cholerae. A stool sample should be collected in Cary-Blair transport medium and sent to the laboratory for analysis. Cholera's pathogenesis involves colonization of the small intestine by V. cholerae which produces an enterotoxin causing a massive outpouring of fluid into the intestine. Laboratory diagnosis of cholera involves culture, microscopy, and biochemical testing of the stool sample. Prophylaxis involves oral rehydration therapy.

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    Second Professional MBBS Degree Examinations, February 2016: Q.P. Code: 205001 Reg. No.

    Uploaded by

    Thushara
    1. The clinical history describes a 24-year-old man admitted with diarrhea for two days who is severely dehydrated and has rice water stool. The probable diagnosis is cholera caused by Vibrio cholerae. A stool sample should be collected in Cary-Blair transport medium and sent to the laboratory for analysis. Cholera's pathogenesis involves colonization of the small intestine by V. cholerae which produces an enterotoxin causing a massive outpouring of fluid into the intestine. Laboratory diagnosis of cholera involves culture, microscopy, and biochemical testing of the stool sample. Prophylaxis involves oral rehydration therapy.

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    of 1

    Q.P. Code: 205001 Reg. no.

    : …………………
    Second Professional MBBS Degree Examinations, February 2016
    Microbiology - Paper I
    Time: 2 Hours Total Marks: 40
    • Answer all questions
    • Draw diagrams wherever necessary

    Essay: (10)
    1. Read the clinical history and answer the following questions:
    A 24 years old man was admitted in medical ward with a history of diarrhea for the
    past two days. On clinical examination he was severely dehydrated. The macroscopic
    appearance of the stool resembled ‘rice water’. Answer the following:
    • What is the probable diagnosis and name the causative agent
    • Mention the method of sample collection and transportation of the sample to the
    laboratory.
    • What is the pathogenesis of the above disease.
    • Describe the laboratory diagnosis.
    • What is the prophylaxis. (1+2+2+4+1=10)

    Short essay: (2x5=10)


    2. Type IV hypersensitivity reaction.
    3. Pathogenesis and laboratory diagnosis of enteric fever.

    Short notes: (10x2=20)


    4. Tyndallisation.
    5. T-helper cells.
    6. Transduction
    7. Bacterial flagella
    8. Enrichment medium.
    9. Lymphogranuloma venereum.
    10. Helicobacter pylori.
    11. Coagulase test.
    12. Nagler reaction.
    13. Types of diarrhoeogenic esherichia coli.
    **********************

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