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  ESTRO  37  
S465  
 
PO-0880 Independent Evaluation Of Dose-Volume PO-0881 Absolute dosimetry with EBT3 films
Histogram (Dvh) Calculation Accuracy F.J. San Miguel Avedillo1, F. Clemente Gutierrez1
1
S. Moragues Femenia1, J.F. Calvo-Ortega1, J. Casals1 Hospital de la Defensa Gomez Ulla, Radiotherapy,
1
HOSPITAL QUIRON BARCELONA, Radiotherapy, madrid, Spain
Barcelona, Spain Purpose or Objective
Most dosimetric quality assurance (QA) devices have low
Purpose or Objective spatial resolution. In treatments with small or modulated
To evaluate the accuracy of DVH calculateion against fields such as intensity modulated radiotherapy (IMRT),
published analytical values. stereotactic body radiation therapy (SBRT) and
Material and Methods stereotactic radiosurgery (SRS), a high resolution dose
The designed datasets and metrics reported by Nelms et measurement technique would be advantageous, and
al (Med Phys. 2015 Aug;42(8):4435-48) have been use as radiochromic film dosimetry is suitable for this purpose.
reference (“ground truth”) to check the accuracy of the In this work, two different multichannel film dosimetry
DVH calculated by Eclipse v 10.0. These datasets include algorithms using the triple channel approximation and a
DICOM RT structure sets (a small sphere, cylinder, and hybrid version have been compared.
cone) created programmatically with axial plane spacing Material and Methods
varying from 0.2 to 3 mm, and synthetic DICOM RT dose EBT3 film was used for QA of IMRT and SBRT cases for a
files generated with 1D linear dose gradient and with grid range of anatomical sites. Dose distributions were
resolution varying from 0.4 to 3 mm. We focused our generated from the film using:
investigation for the scenario of CT scans with 1 mm axial 1. Red channel only
spacing and 1 mm calculation grid size, as used routinely 2. Méndez multichannel algorithm using the
in our cranial stereotactic (SRS) plans. DVHs for 20 truncated normal distribution (TN) [1]
combinations RT structure/RT dose file were analyzed. 3. Pérez-Azorín multichannel algorithm [2]
Differences (Eclipse vs. ground truth) in the following 4. A hybrid of the Méndez and Pérez-Azorín
metrics were calculated: structure volume (V), Dmax, algorithms developed in his study.
Dmin, D99%, D95%, D5%, D1% (where Dx% is the dose to All images were analysed at the same resolution. An
x% volume), and D0.03 cm3 (minimum dose at 0.03 cm3). adaptive median filter was used to minimise noise
Differences are referred as local percent differences, i.e, dependencies and the calibration curve was fitted to a
all normalized based on the ground truth values reported rational parametric form. To perform absolute dosimetry,
by Nelms et al. net optical density was used rather than pixel value.
Results OmniPro I’mRT software was used to perform absolute
Table 1 shows the differences obtained. Differences on gamma analysis using 3%/3mm and 2%2mm criteria on a
volume metric were within 2.5%. Very large differences 20% threshold comparing the various generated
(up to 70%) were found on Dmin, which were reduced distributions from film to the calculated distribution from
within 10% for D99%. Better agreement (within 5%) was the treatment planning system[M1] (TPS) (Monaco v5,
noted for D95%. Differences on remaining metrics were Elekta). All plans were calculated in the same TPS
within 5%. Results
Figure 1 shows a representative dose profile comparison
from a bilateral breast case comparing the hybrid
algorithm (4) from EBT3 film with the TPS.
Table 1 depicts the gamma analysis results for a range of
IMRT and SBRT cases. Dose delivered ranged from 180
cGy to 1800 cGy.

Conclusion
In SRS plans are commonly normalized such as D99% in
target volume is equal to the prescribed dose. As large Figure 1: Dose profile of a bilateral breast case
differences (up to 10%) have been noted on D99%, it comparing QA dose calculation from the Monaco TPS
seems reasonable to normalize the SRS plan using the (green) with the measured dose determinad from and
D95% metric instead of D99%. EBT3 film using the hybrid algorithm (4 )(red).

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