a subjective feeling of tiredness that has a gradual onset.

Unlike weakness, fatigue can be

alleviated by periods of rest. Fatigue can have physical or mental causes. Physical fatigue is the
transient inability of a muscle to maintain optimal physical performance, and is made more severe
by intense physical exercise.[1][2][3] Mental fatigue is a transient decrease in maximal cognitive
performance resulting from prolonged periods of cognitive activity. It can manifest
as somnolence, lethargy, or directed attention fatigue.[4]
Medically, fatigue is a non-specific symptom, which means that it has many possible causes and
accompanies many different conditions. Fatigue is considered a symptom, rather than a sign,
because i