A.

EXPERIMENT RESULT
No Result of Experiment
Assumption/
Experiment Procedures Conclusion
. Before After Reaction

1. 1. Synthesis of Aspirin - Dry salisilic acid : ‐ 2,5 gram of dry Mass of aspirin is
wie powder salysilic acid + 0,4gram
2,5 grams of dry salicylic acid
- Anhydride acetic 3,75 gram
1. Entered into Erlenmeyer 125 mL acid : coloeless anhydride acei +
2. Added 3,75 grams of anhydrate solution acid : White turid H2SO4
acetic acid - H2SO4 solution
3. Added 3 drops of concentrated concentrated : ‐ + H2SO4 : White
H2SO4
colorless solution turid solution
4. Shaked until homogeneous
5. Heated in 50 - 60℃ temperature smoky ‐ Heated in 50-60°
of water bath while shaking - Ethanol 96 % : C : white turbid
slowly in 5 minutes colorless souion (souble) +
6. Cooled at 25℃ temperature while - Aquades : ‐ Salisiyc solution (aspirin)
shaking colorless filtered wih
7. Added 37,5 mL aquadest then
shaked
buchner funner :
8. Filtered the precipitation with Filtrate :colorless
buchner funnel + filtrate paper Residu : white
powder (acetic acid)
Filtrate Residue ‐ Residue + ethanol
+ aqudes :
colorless
No Result of Experiment
Assumption/
Experiment Procedures Conclusion
. Before After Reaction

‐ Residue + ethanol
v + aqudes +
9. Entered into Erlenmeyer 125 mL
10. Added 7,5 mL ethanol 96% and 25 heated :
mL aquadest homogeneous
11. Heated above the burner until solvent solution
boiled while shaking ‐ Weighed : 0,4 +
12. Added water while shaking until the
gram FeCl3
crystal fully dissolved
13. Measure the volume of water used ‐ Melting point :
14. Added some drops of water until 138° C
homogeneous ‐ Tested with
15. Filtered in hot condition sing buchner FeCl3 : purple
funner equipped by suction flask
16. Filtered the precipitation with
buchner funnel + filtrate paper

Filtrate Residue

19. Heated until colorless

20. Cooled at 25℃ temperature until
formed crystal
21. Filtered with filter paper

v
No Result of Experiment
Assumption/
Experiment Procedures Conclusion
. Before After Reaction

v
Residue

19. Dried in the desiccator

20. Measure the mass
21. Compared the melting melting point
with the initial substance
22. Tested the purity of aspirin using FeCl3
solution

Mass and melting

point of asirin
No Result of Experiment
Assumption/
Experiment Procedures Conclusion
. Before After Reaction

2. 2. Recrystallization - Dry Salisilyc - Salisilyc acid + Water is good solvent

1 gram of dry salicylic acid acid : white aquades :
for recrystalization
powder insoluble (turbid
1. Entered into Erlenmeyer 125 mL + 5 solution) (s) + H2O (l)
- Aquades :
mL water - Heated + 28 mL
colorless of aquades :
2. Heated above the burner until
solvent boiled while shaking solule, colorless
3. Added water while shaking until the solution (salisilyc
crystal fully dissolved solution)
4. Measure the volume of water used - Salisilyc solution
filtered with (aq)
5. Add some drop of water until
homogeneous buchner funnel :
6. Filtrated in hot condition using crystal of
buchner funnel equippedby sucktion salisilyc acid
flask formed
- Filtrate : +
Filtrate Residue Filtere and heated
FeCl3
: colorles haf
7. Moved into beaker glass dissoved
8. Boiled until dissoleved - Cooled : crystal
9. Cooled at 25℃ temperature until of salisilyc acid
formed crystal formed
10. Filtered with buchner funnel - Crystal filtered :
crystal of
salisilyc acid
No Result of Experiment
Assumption/
Experiment Procedures Conclusion
. Before After Reaction

- Mass of salisilyc
acid : 0,4 gram
- Melting point :
159° C
Filtrate Residue - Tested with FeCl3
: purple
11. Dried in desiccator
12. Measure the mass
13. Composed melting point
with that initial substance

Mass and melting point