CHM556

ORGANIC CHEMISTRY II LABORATORY

Contact hours: 3 hours/week
Laboratory textbook: Pavia, Lampman, Kriz and Engel, Introduction to Organic
Laboratory Techniques 3rd Edition (2011)
Laboratory: M606

Students must obtain a copy of the textbook. The instruction sheets only contain brief
guidelines to the experiments but the detailed procedural information must be referred
to the textbook.

The experiments selected from the laboratory textbook will reinforce the theory and
concepts studied in Organic Chemistry II. The experiments involve laboratory
techniques such as reflux, distillation, extraction, recrystallization and melting point
determination, synthesis of organic compounds and separations of mixtures. Analysis
of compounds using IR and NMR spectroscopy will also be included.

The Techniques

Students are required read and understand the various techniques that will be covered
in the laboratory sessions from the textbook.

Techniques Page
1. Laboratory Safety 6
2. Laboratory Glassware: Care and Cleaning 31
3. Measurement of Volume and Weight 39
4. Heating and Cooling Methods 58
5. Reaction Methods (Eg: Distillation, Reflux) 68
6. Filtration 90
7. Physical Constants of Solids: The Melting Point 103
8. Crystallization: Purification of Solids 122
9. Extractions, Separations and Drying Agents 141
10. Simple Distillation 179
11. Thin Layer Chromatography 261
12. Infrared Spectroscopy 311
13. NMR Spectroscopy (Proton NMR) 346
14. NMR Spectroscopy (Carbon-13 NMR) 383

Laboratory Note Book

Please read Technique 2 on page 23 on the Laboratory Note Book, Calculations and
Records carefully. The laboratory note book is mandatory and a student will not be
allowed to conduct the experiment without a laboratory note book. Only hard bound
notebook is acceptable. This note book is required for the pre-laboratory preparations
as well as recording results, data and observation of each experiment. The pre-
laboratory preparations must include not only procedural notes but also reactions and
calculations.

Assessment and Grading

The laboratory sessions contribute 20% of the course grade. The success of your
experiments will depend on how well you conduct the experiments to achieve the
objectives. This is reflected in the marks obtained. The marks for each experiment
will come from the following:

A. Pre-laboratory preparations 2 marks

(assessed from the lab note books)
B. Laboratory techniques 1 marks
(performance in the lab)
C. Laboratory reports 17 marks
(all reports are individual work)
Total 20 marks

A well written report is vital in achieving a good grade. Besides conducting the
experiments carefully, the students are expected to write a good report which will
reflect a good understanding of chemistry behind the experiments.

1. All laboratory reports must be typed and submitted one week after the
experiments.

2. The cover page should contain the following information: Course name,
Course code, number and title of experiment, name of student, name of
partners (for group work), name of lecturer, and date of experiment and date
of submission of report.

3. The following marking scheme table must be included with the laboratory
report.

4. Should the student fail to submit the week’s report, the student is given
maximum of 3 marks (for prelab and technique). Marks will also be
deducted for late submission of report.

5. No report will be accepted (no marks given) from students who did not
perform the week’s experiment.

6. Students who missed any lab session (with medical certificate) will be
graded based on the remaining number of experiments.
Laboratory Report Marking Scheme

Full Marks
Mark(s) (to be filled by lecturer)
Objective of the Experiment 1.0
Introduction 2.0
Experimental Procedure 1.0
Results and Observations 3.0
Calculations 3.0
Discussion 2.0
Conclusion 1.0
Answers to Questions 3.0
References 1.0
Pre-laboratory preparations 2.0
Laboratory techniques 1.0
Total Marks 20