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Journal Massage Untuk Bell Palsy
Journal Massage Untuk Bell Palsy
Journal Massage Untuk Bell Palsy
Clinical Rehabilitation
25(7) 649–658
Facial exercise therapy for facial ! The Author(s) 2011
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Abstract
The effectiveness of facial exercises therapy for facial palsy has been debated in systematic reviews but its
effects are still not totally explained.
Objective: To perform a systematic review with meta-analysis to evaluate the effects of facial exercise
therapy for facial palsy.
Data sources: A search was performed in the following databases: Cochrane Controlled Trials Register
Library, Cochrane Disease Group Trials Register, MEDLINE, EMBASE, LILACS, PEDro, Scielo and DARE
from 1966 to 2010; the following keywords were used: ‘idiopathic facial palsy’, ‘facial paralysis’, ‘Bell’s
palsy’, ‘physical therapy’, ‘exercise movement techniques’, ‘facial exercises’, ‘mime therapy’ ‘facial expres-
sion’, ‘massage’ and ‘randomized controlled trials’.
Review methods: The inclusion criteria were studies with facial exercises, associated or not with mirror
biofeedback, to treat facial palsy.
Results: One hundred and thirty-two studies were found but only six met the inclusion criteria. All the
studies were evaluated by two independent reviewers, following the recommendations of Cochrane
Collaboration Handbook for assessment of risk of bias (kappa coefficient ¼ 0.8). Only one study pre-
sented sufficient data to perform the meta-analysis, and significant improvements in functionality was
found for the experimental group (standardized mean difference (SMD) ¼ 13.90; 95% confidence interval
(CI) 4.31, 23.49; P ¼ 0.005).
Conclusion: Facial exercise therapy is effective for facial palsy for the outcome functionality.
Keywords
Physical therapy, exercise, meta-analysis, neurological rehabilitation
Received 31 May 2010; accepted 5 December 2010
4
Faculdades Integradas Aparicio Carvalho and Faculdade
Interamericana of Porto Velho, Brazil
5
Physiotherapy Department, Universidade Estadual de Londrina,
1
MSc Programme in Physical Education, Universidade Estadual Londrina, Brazil
de Londrina-UEM, Londrina, Brazil Corresponding author:
2
Laboratory of Kinesiologic Electromyography and Kinematic, Jefferson Rosa Cardoso, Physiotherapy Department, University
Londrina, Parana, Brazil Hospital, Universidade Estadual de Londrina, Av. Robert Koch,
3
MSc Programme in Rehabilitation, Universidade Estadual de 60. Londrina PR, Brazil 86038-440
Londrina-UNOPAR, Londrina, Brazil Email: jeffcar@uel.br
Caribbean Health Science, 1982–2010), Pedro Brackmann in 1985. This scale analyses the sym-
(Physiotherapy Evidence Database), Cinahl metry, synkinesis, stiffness and global mobility
(1982–2010), Dare (Database of Reviews of of the face. It is divided into six categories
Effects), and Scielo (Scientific Electronic (normal, mild dysfunction, moderate dysfunc-
Library Online, 1998–2010). There were no tion, moderately severe dysfunction, severe dys-
restrictions with regard to language or publica- function and total paralysis) and is a 0–6 point
tion date. This search strategy combined the fol- scale with 6 representing total paralysis.14
lowing specific subject (MeSH) headings and
free-text words: (a) type of disease – idiopathic (b) Linear Measurement Index. This is an
facial palsy, facial paralysis and Bell’s palsy; (b) alternative to the House–Brackmann Scale
type of intervention – physical therapy, exercise developed by Burres and Fisch.15 It analyses
movement techniques, facial exercises, mime the symmetry and global function of the face
therapy or facial expression and massage; and, in an objective and quantitative form. It uses a
(c) type of study – randomized controlled trials, 100-point scale, with higher scores indicating
controlled clinical trials, systematic review and less impairment and handicap.
meta-analysis. Manual searches were also per-
formed in specialized journals. (c) Facial Disability Index. Developed by Van
Swearingen and Brach,16 this questionnaire has
ten items that evaluate patients’ physical and
Selection
social aspects (mastication, deglutition, commu-
The studies selected for this review were ran- nication, labial mobility, emotional alterations
domized controlled trials that analysed both and social integration). It uses a 100-point
mirror biofeedback facial exercises and conven- scale, with higher scores indicating less impair-
tional exercises performed with a therapist as ment and handicap.
treatment for patients with facial palsy. Facial
mime or expression exercises serve the following (d) Lip-length (LL) and Snout (S)
functions: to stimulate both functional move- Indices. These use the ratio between the inter-
ments of the face and facial expression, to pro- commissural distances (ICD) to assess the func-
mote the symmetry of the face, to control and to tioning of the perioral muscles by mouth
reduce synkinesis, to reintegrate emotional mobility. The length of the lips can be measured
expressions and to maintain active musculature in two ways: by pulling the corners of the mouth
and movement perception.13 Studies that apart as far as possible and by pushing the cor-
reported the use of any other type of treatment, ners together. Labial mobility is evaluated by
such as drugs, surgery, electrotherapy or combi- the distance between the labial joints in various
nations of these, were excluded. The outcome movements.17
measures considered were: facial symmetry,
synkinesis, muscle stiffness, labial mobility and (e) Five-Point Scale. This is a subjective scale
patient physical and psychosocial aspects relat- that evaluates synkinesis and stiffness. Patients
ing to facial palsy. For evaluation of these out- indicate the stiffness they experience on a
comes, therapists scored their patients using the 5-point scale, with 5 being very stiff.18
scales described as follows:
(f) Sunnybrook Facial Grading System. The
(a) House–Brackmann Scale. Classified as a system measures three components of facial
universal scale by the American Academy of asymmetry: Resting asymmetry (scored from
Otolaryngology – Head and Neck Surgery – 0–4 with 4 being the most asymmetrical), sym-
Committee of Disorders of the Facial Nerve, metry of voluntary movement (scored from 0–5
it was proposed and modified by House and with 5 being the most symmetrical) and
synkinesis (scored from 0–3 with 3 being the Trials Register Library ¼ 12, Embase ¼ 28,
worst). A perfect score of 100 points represents Medline ¼ 24, Lilacs ¼ 43, Pedro ¼ 04,
normal facial symmetry.19 Dare ¼ 08 and Scielo ¼ 13. Twenty-six studies
were indexed in two or more databases resulting
in duplication. One hundred studies were
Validity assessment
excluded because they did not match the inclu-
The two authors collected and analysed titles sion criteria (Figure 1). Six studies met the inclu-
and abstracts of all studies found, as well as sion criteria (Table 1).
the information about participants, differences Ross et al.22 randomized 31 patients who had
at baseline, interventions, outcomes and results been suffering from facial palsy for a minimum
of the randomized controlled trials using a data of 18 months into three groups. Group I
collection form. When data were not available included 13 patients who did only mirror exer-
or were unclear, the author of the original study cises. Group II included 11 patients who did
was contacted to request relevant information. mirror exercises as well as 30-minute electromy-
Two independent authors evaluated the risk of ography biofeedback sessions. Group III
bias of the included studies following the recom- included 7 patients did not undergo treatment
mendations of the Cochrane Collaboration and served as controls. All patients were objec-
Handbook20 and assigned a score according to the tively evaluated prior to the study and at six and
criteria. In case of disagreement, a third reviewer twelve months afterwards using three different
intervened and made a judgement to prevent any techniques described in Table 1.
inter-observer bias. The assessed items were: ade- Segal et al.23 analysed 10 patients who had
quate sequence generation, allocation concealment, had from 0.5 to 27 years of facial palsy, random-
blinding, follow-up, intention-to-treat analysis, izing them into two groups with five participants
incomplete outcome data and selective outcome each. Group I was treated with a conventional
reporting. All items were classified as ‘Yes’ when neuromuscular retraining programme consisting
the criteria were clearly described or ‘No’ when the of patient facial anatomy education, relaxation,
item was unclear or not cited. All data were entered face-tapping exercises, biofeedback training
into the analysis program by one review author. using a mirror or electromyography and specific
This review following the PRISMA Statement.21 facial exercises. Group II received the same
The descriptive results were presented in treatment except that each patient performed a
tables. Meta-analysis was performed in order single maximal movement and was obliged to
to compare the outcomes of functionality stop when synkinesis occurred. Subsequent
between the mime therapy group and the control movements were at half of this maximum. All
group. The standardized mean difference (SMD) patients did therapy three times a week for four
with 95% confidence intervals (CI) was calcu- weeks, totalling 12 sessions. Subjects were also
lated because the outcome was measured using assessed weekly using the House Scale.
different instruments. The kappa coefficient Beurskens and Heymans18 divided 50 patients
was used to assess agreement among assessors who had had unilateral peripheral facial paraly-
for quality of randomized controlled trial. sis for at least nine months into two groups. The
Statistical analysis was performed using control group had 25 participants and received
Review Manager 5 software and SPSS 15.0 no intervention. The experimental group
(SPSS Inc., Chicago, IL, USA). received mime therapy during ten weekly
45-minute sessions. The therapy was composed
of self-massage of the face and neck, breathing
Results
and relaxation exercises, specific exercises for the
The literature search resulted in 132 abstracts, face to coordinate both halves and to decrease
distributed as follows: Cochrane Controlled synkinesis, lip-closure exercises, letter and word
24 28 43 4 8 12 13
citations citations citations citations citations citations citations
Citations excluded
(n =44)
Abstracts excluded
(n= 30)
pronunciation exercises, emotional expression into an experimental group (n ¼ 29) and a control
exercises and guidance about communication group (n ¼ 30). The experimental group was trea-
possibilities. Patients performed the exercises ted with techniques tailored to each patient that
daily at home using a homework manual. involved mirror biofeedback. The patients did
Nakamura et al.24 studied 27 patients, 10 of 5–10 repetitions of facial exercises three times a
whom had a diagnosis of Bell’s palsy and 17 of day in the initial stages. They were instructed to
herpes zoster oticus. Twelve patients did 30 min- perform facial movements on the affected side
utes of daily home training that consisted of without the voluntary movement of the unaf-
trying to keep their eyes open symmetrically fected side. The control group received electrical
during three designated mouth movements stimulation six days a week for a period of two
(pursing the lips, baring the teeth, and puffing weeks, gross facial expression exercises and mas-
out the cheeks) with mirror biofeedback. Fifteen sage. Both groups were instructed to do these
patients served as controls and did not receive exercises daily at home for three months.
any kind of intervention. Barbara et al.26 published a randomized trial
Manikandan25 did a study with 59 patients with 20 patients who underwent medical treat-
diagnosed with Bell’s palsy who were allocated ment, a combination of antiviral and steroid
(2007)25 palsy niques (facial neuromuscu- the onset treatment and is more effective than
G2 ¼ 30 subjects with lar re-education) that were after a period of 3 months conventional therapeutic
the same diagnosis served tailored to each patient in measures in improving the
as controls 3 sessions per day for 6 facial symmetry in patients
days per week for a period with Bell’s palsy
of 2 weeks
G2 ¼ Received conven-
tional therapeutic mea-
sures (electrical
stimulation, gross facial
expression exercises and
massage for the same
period as G1
Barbara et al. G1 ¼ 10 patients with Bell’s Medical treatment for 10 House–Brackmann Facial When applied at an early
(2009)26 palsy days. Then, patients were Grading System (Six stage, Kabat’s rehabilita-
G2 ¼ 9 patients with the divided in two groups: grades, where grade I rep- tion was proved to achieve
same diagnosis were G1 ¼ Patients who resents normal function better and faster recovery
placed on a waiting list for received physical therapy and grade VI represents in comparison to the non-
three months. for 15 days, once a day total paralysis) rehab patients
G3 ¼ Patients from G2 ¼ Non-rehabilitation Amplitude of the com-
group 2 who did not show group pound motor action
signs of clinical recovery G3 ¼ Kabat́s rehabilitation potential
after 2 weeks of exclusive (after day 15)
drugs, continuously for 15 days. After that, they presented the mean and standard deviation for
were divided in two groups: The first group, with functionality. This is for both pre- and
nine patients, did a rehabilitation programme post-treatment experimental and control group
with one session per day for six days, and con- outcomes. The scarcity of the randomized con-
tinued for 15 days. The second group, with 11 trolled trials as well as the low quality of the
patients did not undergo the physical rehabilita- randomized controlled trials found in this
tion. These second group was divided again and review should be a cause for concern to health
formed a third group with patients who did not professionals since few studies for this type of
show signs of clinical recovery after two weeks therapy have been carried out.
of exclusive medical treatment and then under- A systematic review about mime therapy for
went a delayed Kabat rehabilitation. This study facial palsy was published in 200812 with four
was not included in this review because the studies. Meta-analysis was not performed
second group division was not randomized. In because the studies had an incompatible combi-
addition to this it creates unnecessary confusion. nation of characteristics such as treatment type,
Agreement between reviewers regarding the time of duration of the intervention and out-
studies’ risk of bias assessment was considered come measures. The study did not demonstrate
perfect (kappa coefficient ¼ 0.8). The most clinical or statistically significant differences
common risks of bias compromising the quality among the different treatment groups.
of the included studies were: allocation conceal- In 2008 the Cochrane Library published a
ment, blinding and intention-to-treat analysis. systematic review of articles about physical ther-
Figure 2 represents the meta-analysis for the func- apy and Bell’s palsy15 including six studies with
tionality outcome of patients who received phys- patients who had an exclusive diagnosis of
ical therapy (25) and the control group (25). The Bell’s palsy and underwent several types of
experimental group did mime therapy for ten treatment: faradic stimulation, galvanic current,
weekly 45-minute sessions, for three months. infrared treatment, massage, self-massage, acu-
The control group received no intervention. puncture and drugs. No statistically significant
This analysis demonstrated a significant improve- inter-group differences were found. Because of
ment in functionality for the experimental group differences in inclusion criteria, only two of the
(SMD ¼ 13.90; 95% CI 4.31, 23.49; P ¼ 0.005). studies included in the above-mentioned review
coincide with those in our systematic review.
The aetiology of facial palsy in the studies
Discussion
included in our review was heterogeneous: 67%
The main goal of this study was to carry out the had Bell’s palsy, 13% herpes zoster, 1% Lyme
meta-analysis to determine the effect of mime disease, 1% trauma, 1% operation trauma, 2%
therapy on facial palsy. This analysis is relevant meningioma and 1% facial neuronal apoptosis.
when making decisions about an effective treat- Future studies must include patients with a sin-
ment protocol for these patients. In this study, gle diagnosis in order to better substantiate
only three randomized controlled trials the effects of mime therapy on facial palsy.
Studies analysing the progression of such patients outcome descriptions. They must include
are also necessary. Only one study with one year patients with the same diagnosis and use valid
of follow-up was found, and the authors con- instruments for outcome measures (e.g. House–
cluded that benefits continued to be stable at Brackmann, Facial Disability System). Outcome
three and twelve months.27 measures must provide information about rest-
The differences in evaluation and description ing asymmetry, symmetry of voluntary move-
of outcomes were limitations for this study. Ross ment and synkinesis. The patients must be
et al.22 used distances between points at rest and evaluated prior to treatment, during treatment,
during facial expressions, standardized photog- immediately after the course of treatment and
raphy from video tapes and facial nerve response again some months later. Quality of life data
to electroneurography and presented the out- both before and after treatment is also impor-
comes in unclear graphics. Segal et al.23 used tant. Such measures will lead to advances in
the House–Brackmann Scale weekly but did our understanding of the efficacy of physical
not show the results of this measure. Their results treatment for these patients.
are described in an unclear table where muscle
movement symmetry score values were counted
and evaluated using an eight-level scale, but the
Implications for practice
number of synkinetic muscles was counted and Mime therapy can improve functionality for
classified with a four-level scale. Nakamura patients with facial palsy. The therapy must consist
et al.24 recorded facial movements and analysed of exercises with mirrors, which are both low cost
them with a computer program to evaluate and easily available, and the patient must help in
movement symmetry, but the results appear in the execution of the movements for both biofeed-
unclear graphics. All the authors were contacted back purposes and to prevent synkinesis. A daily
in order to collect better information but we home programme should be prescribed for
received no responses. For this reason, only patients in order to help the evolution of treatment.
three studies were included in the meta-analysis.
Allocation concealment and intention-
to-treat analysis were the most common risks
Conclusion
of bias found. Allocation concealment is neces- This systematic review suggests that mime ther-
sary to prevent differences in measured or apy is effective for facial palsy for the outcome
unmeasured baseline characteristics because of functionality.
the way participants were selected or assigned.
The intention-to-treat analysis is necessary to
prevent bias caused by the loss of participants, Clinical messages
which may disrupt the baseline equivalence . Facial exercises therapy may improve
established. Blinding is difficult for this type of facial functionality.
treatment because both therapist and patient are . This therapy may be included to assist
aware of treatment. The bias found in the stud- with the functionality recovery of patients
ies we reviewed can be partially explained by the with facial palsy.
fact that the CONSORT Statement was only
established in 1999.
References 16. VanSwearingen JM and Brach JS. The facial index dis-
ability: reliability and validity of disability assessment
1. Beurskens CH and Heymans PG. Physiotherapy in
instrument for disorders of the facial neuromuscular
patients with facial nerve paresis: description of out-
system. Phys Ther 1996; 76: 1288–1300.
comes. Am J Otolaryngol 2004; 6: 394–400.
17. Jansen C, Devrise PP, Jennekens FGI and Wijnne HJA.
2. Martyn CN and Hughes RA. Epidemiology of periph-
Lip-length and Snout Index in Bell’s palsy. Acta
eral neuropathy. J Neurol Neurosurg Psychiatry 1997;
Otolaryngol 1991; 111: 1065–1069.
62: 310–318.
18. Beurskens CH and Heymans PG. Positive effect of
3. Shafshak TS. The treatment of facial palsy from the
spoils therapy on sequelae of facial paralysis: stiffness,
point of view of physical and medicine rehabilitation.
lip mobility, and social and physical aspects of facial
Eura Medicophys 2006; 42: 41–47.
disability. Otol Neurotol 2003; 24: 677–681.
4. Rath B, Linder T, Cornblath D, et al. All that palsies is
19. Ross BG, Fradet G and Nedzelski JM. Development of
not Bell’s – the need to define Bell’s palsy as an adverse
a sensitive clinical facial grading system. Otolaryngol
event following immunization. Vaccine 2007; 26: 1–14.
Head Neck Surg 1996; 114: 380–386.
5. Lazarini PR, Vianna MF, Alcantara MPA, Scalia RA
20. Higgins JPT, Green S. Cochrane handbook for systematic
and Caiaffa Filho HH. Herpes simplex virus in the
reviews of interventions Version 5.0.0 (updated February
saliva of peripheral Bell’s palsy patients. Bras J
2008). The Cochrane Collaboration, 2008.
Otorrinolaringol 2006; 72: 7–11.
21. Moher D, Liberati A, Tetzlaff J, Altman DG; PRISMA
6. Hadlock T and Cheney ML. Facial reanimation: an
Group. Preferred reporting items for systematic reviews
invited review and commentary. Arch Facial Plast Surg
and meta-analyses: the PRISMA statement. BMJ 2009;
2008; 6: 413–417.
339: b2535.
7. Quinn R and Cramp F. The efficacy of electrotherapy
22. Ross B, Nedzelski JM and McLean JA. Efficacy of feed-
for Bell’s palsy: the systematic review. Phys Ther Rev
back training in long-standing facial nerve paresis.
2003; 8: 151–164.
Laryngoscope 1991; 101: 744–750.
8. Costa ACT, Garcia JM and Freitas MRG. Outlying
23. Segal B, Hunter T, Danys I, Freedman C and BMR
facial paralysis: analysis of 40 patients. Bras J Neurol
Black M. Minimizing synkinesis during rehabilitation
1988; 24: 139–141.
of the paralysed face: preliminary assessment of a new
9. Flores PF, Zazueta RM and Garcı́a LH. Tratamiento de
small-movement therapy. J Otolaryngol 1995; 3:
la parálisis facial periférica idiopática: terapia fı́sica
149–153.
versus prednisona. Rev Med Inst Mex Seguro Soc
24. Nakamura K, Toda N, Sakamaki K, Kashima K and
1998; 36: 217–221.
Takeda N. Biofeedback rehabilitation for prevention of
10. Teixeira LJ, Soares BG, Vieira VP, Prado GF. Physical
synkinesis after facial palsy. Otolaryngol Head Neck
therapy for Bell s palsy (idiopathic facial paralysis).
Surg 2003; 128: 539–543.
Cochrane Database Syst Rev 2008; 3: CD006283.
25. Manikandan N. Effect of facial neuromuscular re-edu-
11. La Touche R, Escalante K, Linares MT and Mesa J.
cation on facial symmetry in patients with Bell’s palsy: a
Effectiveness of physiotherapy treatment in peripheral
randomized controlled trial. Clin Rehabil 2007; 21:
facial palsy. A systematic review. Rev Neurol 2008; 12:
338–343.
714–718.
26. Barbara M, Antonini G, Vestri A, Volpini L and Monini
12. Cardoso JR, Teixeira EC, Moreira MD, Fávero FM,
S. Role of Kabat physical rehabilitation in Bell’s palsy: a
Fontes SV and Bulle de Oliveira AS. Effects of exercises
randomized trial. Acta Otolaryngol 2009; 8: 1–6.
on Bell’s palsy: systematic review of randomized con-
27. Beurskens CH, Heymans PG and Oostendorp RA.
trolled trials. Otol Neurotol 2008; 4: 557–560.
Stability of benefits of mime therapy in sequelae of
13. Allen D, Dunn L. Aciclovir or valaciclovir for Bell’s
facial nerve paresis during a 1 year period. Otol
palsy (idiopathic facial paralysis). Cochrane Database
Neurotol 2006; 7: 1037–1042.
Syst Rev 2004; 3: CD001869.
28. Schulz KF, Altman DG and Moher D. Update guide-
14. House JW and Brackmann OF. Facial nerve grading
lines for reporting parallel-group randomized trials. Ann
system. Arch Otolaryngol Head Neck Surg 1985; 93:
Intern Med 2010; 152: 1–7.
146–147.
15. Burres SA. Facial biomechanics: the standard of
normal. Laryngoscope 1985; 95: 708–714.