Drugs and their Antidotes

The need of antidotes for different drugs happened due to the toxicology of
drugs or we may say that due to the misuse of drugs.
Toxicology:
The study of the effect of poisons on the function of living systems
"All things are poison and nothing is without poison, only the dose permits something not
to be poisonous."
Paracelsus (1493-1541) ‘Grandfather of Toxicology’

Therapeutic effect Increasing Dose Toxic effect

List of common drugs and their Antidotes

Name of Drug Antidote

1. Acetaminophen Acetylcycteine
2. Curare Tensilon
3. coumadin Vita K
4. Digitalis Digibind
5. Cyanide poisoning Methylene blue
6. Benzodiazepine Flumazenil
7. Iron Desferal
8. Lead EDTA , BAL
9. Ethylene poisoning Antizol
10. Magnesium sulphate Calcium gluconate
11. Penicillin Epinephrine
12. Morphine sulphate Naloxone hydrochloride
13. Vincristine Hyaluronidase
14. Neostigmine Pralidoxime chloride
15. Mestinon Atropine sulfate
16. Ethylene glycol Ethanol
17. Caffeine Esmolol
18. Beta blockers Glucagon
19. Barbiturates Charcoal
20. Meyaproterenol Esnolol
21. Cholinesterase inhibitors Atropine
22. Heparine Protamine sulfate
23. Isoniazid Vita b6
24. Iron salts Deferoxamine

1
 25. Warfarin Vita K
26. Salicylates Charcoal
27. Quinidine Sodium bicarbonate
28. Muscarinic receptor blockers Physostigmine
29. Calcium channel blockers Glucagon
30. Cyclophosphamide MESNA
31. Dopamine Phentolamie
32. Fluorouracil Leucoverin calcium
33. Insuline inj Glucose
34. Methotrexate Leucovorine calcium
35. Tricyclic antidepressants Phyostigmine
36. Potassium Insuline and glucose
37. Chloroqunine Diazepam
38. Amphetamine Propranolol
39. Arsenic Dimercaprol
40. Carbamate Atropine
41. MAOI Phentolamine

References
 The antidote inside the world of new pharma by Barry Werth (2014)
 Text book of pharmacology by Lipponcott
 Antidotes Principles and Clinical Applications by Robert Flanagan (2003)
 Medical toxicology by Richerd C. Dart (2004)