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Development of Tooth
Development of Tooth
Piyush verma
MDS 1st year
Dept of Pedodontics & Preventive Dentistry
CONTENTS
1. Introduction
2. Dental Lamina
3. Vestibular Lamina
4. Tooth development
5. Developmental stages
• Bud stage
• Cap stage
• Bell stage
• Advanced bell stage
6. Hertwig’s epithelial root sheath and root formation
7. Conclusion
8. References
INTRODUCTION
Tooth formation occurs in the 6th week of intrauterine
life with the formation of primary epithelial band. At
about 7th week the primary epithelial band divides into
a lingual process called dental lamina & a buccal process
called vestibular lamina. All deciduous teeth arises from
dental lamina, later the permanent successors arise
from its lingual extension & permanent molars from its
distal extension
• The primitive oral cavity, or stomodeum, is lined by stratified squamous
epithelium called the oral ectoderm
• The oral ectoderm contacts the endoderm of the foregut to form the
buccopharyngeal membrane
• Membrane ruptures at about 27th day of gestation and the primitive oral
cavity establishes a connection with the foregut
• Most of the connective tissue cells underlying the oral ectoderm are of
neural crest or ectomesenchyme in origin
• These cells instruct the overlying ectoderm to start the tooth development,
which begins in the anterior portion of the future maxilla & mandible and
proceeds posteriorly
DENTAL LAMINA
• 2- 3 weeks after the rupture of buccopharyngeal membrane, certain areas of
basal cells of oral ectoderm proliferate rapidly, leading to the formation of
primary epithelial band
• The band invades the underlying ectomesenchyme along each of the horse-
shoe shaped future dental arches.
• At about 7th week the primary epithelial band divides into an inner (lingual)
process called Dental Lamina & an outer ( buccal) process called Vestibular
Lamina
• The dental lamina serves as the primordium for the ectodermal portion of
the deciduous teeth
• Later during the development of jaws, permanent molars arise directly from
the distal extension of the dental lamina
• The successors of the deciduous teeth develop from a lingual extension of the
free end of the dental lamina opposite to the enamel organ of each deciduous
teeth.
The lingual extension of the dental lamina is named the successional lamina &
develops from the 5th month in utero ( permanent central incisor) to the 10th
month of age (second premolar)
FATE OF DENTAL LAMINA
• It is evident that total activity of dental lamina exceeds over a period of atleast 5 yrs
• As the teeth continue to develop, they loose their connection with the dental lamina
•They later break up by mesenchymal invasion, which is at first incomplete and does not
perforate the total thickness of the lamina
• Fragmentation of the dental lamina progresses toward the developing enamel
organ
• Any particular portion of the dental lamina functions for a much briefer period
since only a relatively short time elapses after initiation of tooth development
before the dental lamina begins to degenerate
• However the dental lamina may still be active in the third molar region after it
has disappeared elsewhere, except for occasional epithelial remnants
CLINICAL CONSIDERATIONS
ANODONTIA
• It is of following types
1. Complete anodontia/ total anodontia
2. Partial anodontia/ sub-Total anodontia
COMPLETE
• Forms-
1. True anodontia
2. Psuedo anodontia
3. False anodontia
PARTIAL
SUPERNUMERARY TEETH
Hyperdontia is the condition of
having supernumerary teeth, or teeth which
appear in addition to the regular number of
teeth
Supernumerary teeth can be classified by
shape and by position. The shapes include:
• Supplemental(where the tooth has a
normal shape for the teeth in that series);
• Tuberculate (also called "barrel shaped");
• Conical (also called "peg shaped");
• Compound odontome (multiple small
tooth-like forms);
• Complex odontome (a disorganized mass of
dental tissue)
• Subsequently hollows and form the oral vestibule between the alveolar portion of
the jaws and the lips and cheeks.
TOOTH DEVELOPMENT
• At certain points along the dental lamina each representing the location of one of the
10 mandibular & 10 maxillary teeth, ectodermal cells multiply rapidly & little knobs
that grow into the underlying mesenchyme
• Each of these little down growths from the dental lamina represents the beginning of
the enamel organ of the tooth bud of a deciduous tooth
• As the cell proliferation occurs each enamel organ takes a shape that resembles a cap
DENTAL PAPILLA
On the inside of the cap, the ectomesenchymal cells increase in number. The
tissue appears more dense than the surrounding mesenchyme and represents
the beginning of the dental papilla
B = Dental Papilla
DENTAL SAC/ DENTAL FOLLICLE
Surrounding the combined enamel organ or dental papilla, the third part of the tooth
bud forms. It is known as dental sac/follicle and it consists of ectomesenchymal cells and
fibres that surrounds the dental papilla and the enamel organ.
C= Dental sac
• Thus the tooth germ consists of ectodermal
component- the enamel organ, the
ectomesenchymal components- the dental papilla
& the dental follicle
• The cells of the dental papilla form the dentin and pulp while the dental sac forms
cementum & periodontal ligament
CAP STAGE / PROLIFERATION
• As the tooth bud continues to proliferate, it does not expand uniformly into a
large sphere
• Instead unequal growth in different parts of the tooth bud leads to the cap
stage which is characterized by a shallow invagination on the deep surface of the
bud
OUTER & INNER ENAMEL EPITHELIUM
• As a result the polygonal cells become star shaped but maintain contact with each
other by their cytoplasmic process
• As the star shaped cells form a cellular network, they are called the stellate reticulum
• The cells in the center of the enamel organ are densely packed and form the
enamel knot
• The ectomesenchymal
condensation i.e the dental papilla &
the dental sac are pronounced
during this stage of dental
development
BELL STAGE / HISTODIFFERENTIATION
• Due to continued uneven growth of the
enamel organ it acquires a bell shape
• These elongated cells are attached to one another by junctional complexes laterally &
to cells in the stratum intermedium by desmosomes
• The cells of the inner enamel epithelium exert a strong influence on the underlying
mesenchymal cells of the dental papilla, which later differentiate into odontoblasts
STRATUM INTERMEDIUM
• A few layers of squamous cells form the stratum intermedium , between the inner
enamel epithelium & the stellate reticulum
• These star shaped cells, having a large processes anastomose with those of adjacent
cells
• As the enamel formation starts., the Stellate reticulum collapses to a narrow zone
thereby reducing the distance between the outer & inner enamel epithelium
OUTER ENAMEL EPITHELIUM
• The cells of the outer enamel epithelium flatten to form low cuboidal cells
• The outer enamel epithelium is thrown into folds which are rich in capillary network,
this provides a source of nutrition for the enamel organ
• Before the inner enamel epithelium begins to produce enamel. Peripheral cells of
the dental papilla differentiate into odontoblasts
• These cuboidal cells later assumes a columnar form & produce dentin
DENTAL LAMINA
• Dental lamina is seem to extend lingually and is termed successional dental lamina
as it gives rise to enamel organs of permanent successors of deciduous teeth
• The enamel organs of deciduous teeth in the bell stage show successional lamina &
their permanent successor teeth in the bud stage
DENTAL SAC
MULBERRY MOLARS
FUSION
Concrescence is a condition
of teeth where
the cementum overlying the roots
of at least two teeth join together.
The cause can sometimes be
attributed to trauma or crowding of
teeth.
Radiographic diagnosis is
mandatory before attempting tooth
extraction
CONCLUSION