SUMMARY The objective ofthe present investigation was to develop the formation of photoresist bast on the hydealeohoicextct ofthe leaves of Pasifloe quadrangulars(L) and to determine its ual. The qusity contol ofthe vegetable drug ws cared out by analyzing the moistre aud insolubie in hydrochloric acid. The preseace of phenolic compounds among them flavonoids in the arial parts of Pasion quadrangular (L) was sterined qualtaivel inthe phytochemical screening The vests 70% thon rato (1:10) and was concerted inthe rlavapoe to which the quay and yell cont otal ashes soluble in wa serial was extracted with contol tests were carried out. The content of phenols and eal Mavonots was quad by spoctrophotometic methods. The in vitro sun protectin factor (SPP) of bth the tydoaleoholc ‘eta andthe cream was detemined by Mans’ method and equation. The best SPF ofthe dy tract was obtained ata concenation of 1000 ppm with a valu of 30.6 which was used asa ass forthe formulation ofthe photoresist ingredions were incorpoatd including olive, svocado and wheat germ oils the Inter being the one that showed the greatest synergy the ntact, btaning an SPF of 40.1 inthe cream. The physical, chemical, mirobiological and quay comtl controls ofthe ream were cared ont, demonstrating is efficacy and safety at the topical level It was confined trough the acolyte stability est tat the cream meets the spoifctionsesblshed withthe COLIPA standards of effixtiveness of cosmese roduets. this ay, the formulation ofa sunscreen base onthe estilo eaves of Pastors qudangulars was obese is recommended to prepare ther types of cosmetic orm from the extrac 5 gs comput powders and make various combinations with other pln extras to determine their efetvenes and level of photoprotetin. Keywords: , , , , ,