CAS No.

7757-82-6
Chemical Name:
Sodium sulfate
Synonyms
kemol;Na2SO4;SALT
CAKE;Crimidesa;Mirabilite;Thenardite;Sal
mirabil;NATRII
SULFAS;Natriumsulfat;GLAUBER'S
SALT
CBNumber:
CB4100946
Molecular Formula:
Na2O4S
Formula Weight:
Sodium sulfate
142.04
MOL File:
7757-82-6.mol
Request For Quotation
Properties Safety Price83 Uses Suppliers 316
Sodium sulfate Properties
Melting point:
884 °C(lit.)
Boiling point:
1700°C
Density
2.68 g/mL at 25 °C(lit.)
refractive index
1.484
storage temp.
Store at RT.
solubility
H2O: 1 M at 20 °C, clear, colorless
form
powder (fine)
color
White
PH
5.2-8.0 (50g/l, H2O, 20℃)
Water Solubility
18.5 mg/L
Sensitive
Hygroscopic
Merck
14,8680
Stability:
Stable. Incompatible with strong acids, aluminium, magnesium, strong bases. Hygroscopic.
CAS DataBase Reference
7757-82-6(CAS DataBase Reference)
NIST Chemistry Reference
Sodium sulfate(7757-82-6)
SAFETY
Hazard Codes Xi

Risk Statements 36/37/38

Safety Statements 24/25

WGK Germany 1

RTECS WE1650000

F 3

TSCA Yes

HS Code 28331100

7757-82-
6(Hazardous
Hazardous Substances Data Substances
Data)

Sodium sulfate price More Price(83)

Product Product CAS
Manufacturer Packaging Price Updated Buy
number description number
7757-82- 2017-11-
Sigma-Aldrich 1.06637 Sodium sulfate 1EA $46.75 Buy
6 08
7757-82- 2017-11-
Sigma-Aldrich 1.06637 Sodium sulfate 2EA $72 Buy
6 08
Sodium sulfate,
Strem 7757-82- 2017-11-
93-1068 anhydrous, 99+% 250g $14 Buy
Chemicals 6 27
(ACS)
Sodium sulfate,
Strem 7757-82- 2017-11-
93-1068 anhydrous, 99+% 1kg $36 Buy
Chemicals 6 27
(ACS)
7757-82- 2017-11-
Sigma-Aldrich 8.22286 Sodium sulfate 1EA $38 Buy
6 08
Sodium sulfate Chemical Properties,Uses,Production
Chemical raw materials
Sodium sulfate is an important chemical raw material and is the main raw material for production of
sodium sulfide, sodium silicate and other chemical products. It can also be used as filler of synthetic
detergent. In the paper industry, it can be used as the cooking agent for the manufacturing of paper
pulp of sulfate.
Sodium sulfate, also known as anhydrous Glauber's salt or anhydrous mirabilite, appears as white
monoclinic crystal or fine powder with the relative density being 2.68 and the melting point being 884
℃. It can be dissolved in water with the aqueous solution being neutral. It is soluble in glycerol and
insoluble in ethanol. It is easy to absorb water when being exposed to become hydrous sodium
sulfate. It is a homogeneous polycrystalline material and is rhombus at a temperature of 32.4~223 ℃
with generating shaped monoclinic crystal at higher temperatures and generating hexagonal crystals
in 241 ℃. When being crystallized from solution, it has high affinity to iron, iron compound and
various kinds of other organic compounds; high-purity, fine-particle anhydrous sodium sulfate is
called as “YuanMingFen”.
There are two kinds of crystalline hydrate compound of sodium sulfate: one is heptahydrate sodium
Na2SO4·7H2O, being white sixty or tetragonal crystal with dehydrating at 24.4 ℃. Another is sodium
sulfate decahydrate Na2SO4·10H2O with conventional name being Glauber's salt, “YuanMingFen”,
insurance powder. It appears as colorless monoclinic crystal with the density being 1.464g/cm3, the
melting point of 32.38 ℃ and loss of crystal water to becomes anhydrous sodium sulfate at 100 ℃. It
is easily soluble in water and is easily weathered in dry air to become a dry white powder. Sodium
sulfate can be used as chemical analysis reagent such as dye testing; printing industry apply it as
mordant agent for making sodium sulfide, glass, water glass, enamel, quantitative measurement of
nitrogen and papermaking pulp. In medical care field, it can be used as the antidotes of medical
diuretics, laxatives and barium salt poisoning. There are also sodium salt crystals precipitated from
salt ponds in winter.
Naturally occurring sulfate mineral is widely distributed with mostly existing in magnesium sulfate
(calcium) complex salt and mirabilite. There are relative large amount of salt lakes in China's Inner
Mongolia, Qinghai, Tibet, and some places of Xinjiang. There is large amount of sodium sulfate in
the salt lake. Industrial preparation of sodium sulfate is mainly isolated from natural mineral or by the
mirabilite dehydration and treatment with sulfuric acid to obtain sodium chloride. Sodium sulfate is
also the byproduct of a lot of chemical industrial production sector and can be extracted from the
waste liquid discharged during the production of viscose fiber and cellophane. In the production of
sodium dichromate, phenols, boric acid, lithium carbonate, and certain pigments, there is also
sodium sulfate as byproduct. Sulfate decahydrate, when being heated to the melting point (32.38 ℃),
it can be dissolved its own crystal water while generating anhydrous salt. This temperature is the
temperature at which the decahydrate salt, anhydrous salt and saturated solution, the three-phases
reaches equilibrium temperature. As long as the three-phase coexists, the temperature is constant.
Therefore the system can be used for as constant temperature bath or for calibration of temperature.
Another feature of sodium sulfate is being prone to become supersaturated solution.
The main function
Sodium sulfate is an important raw material in the manufacturing of glass and paper with the
maximum usage amount in the paper and cellulose industry which accounts for around 70% of the
total amount. Sodium sulfate is the component of synthetic detergent and is a neutral salt. It can be
added to the detergent to reduce the surface tension as well as increases the solubility of the
detergent. It is also be used as the dye diluent and the auxiliary agent of the dye printing, as direct
dyes, sulfur dyes, vat dyes and other accelerant of dyed cotton fiber, as retarding agent for direct
dye silk. In the chemical industry, it can be used as the raw material for the manufacturing of sodium
sulfide, gypsum, sodium silicate and other chemical products. It has been now developed of the
method for making sulfuric acid, sulfur, soda ash, ammonium sulfate and other products with sodium
sulfate. However, due to the high cost of these methods, it has not yet been widely applied. It has
been commonly used by laboratory system for using sodium sulfate as cold agent. Glauber's salt
has been used as a laxative medicine. The sodium sulfate entering into the body is largely stuck in
the gastrointestinal tract without being absorbed and being maintained at certain penetration. It can
increase the volume of the intestines and induce intestinal peristalsis with diarrhea effect. Sodium
sulfate is the antidote of barium and lead poisoning. Upon lead poisoning, people can apply gastric
lavage with 10% Glauber's salt or orally administer 1 to 2% sodium sulfate solution.
The above information is edited by the chemicalbook of Dai Xiongfeng.
Pharmacological effects
Apply oral administration of small amount with its ionic and osmotic pressure effect being able to
slightly stimulate the digestive tract mucosa and causes a slight increase of the gastrointestinal
secretion and a slight increase in the movement, therefore it has stomachic effect.
Orally administer a large amount with a lot of sodium sulfate being dissolved in large amount of
water for oral administration. Since the ions are not easily absorbed and can maintain large amount
of water in the intestines and can mechanically stimulate the intestinal mucosa and can soften the
fecal matter and accelerate the defecation. It is clinically mainly used in the treatment of large
intestine constipation, eliminating the intestinal toxins as well as getting rid of parasites.
Solubility in water (g / 100ml)
The amount (grams) can be dissolved per 100 ml of water at different temperatures (℃):
4.9g/0 ℃; 9.1g/10 ℃; 19.5g/20 ℃; 40.8g/30 ℃; 48.8g/40 ℃
45.3g/60 ℃; 43.7g/80 ℃; 42.7g/90 ℃; 42.5g/100 ℃
Identification test
Sodium test of 5% of the sample liquid (IT-28) and sulfate test (IT-29) result is positive.
Content Analysis
Accurately weigh 500 mg of sample pre-dried for 4 h at 105 ℃ and dissolve it in 200ml of water; Add
1 mL of hydrochloric acid and heat to boiling. Under constant stirring, add in portions of a small
amount (around 10 mL) of hot barium chloride test solution (TS-37), heat on a steam bath for 1h and
filter out the precipitate with further washing with water until being chloride-free. After drying, burn
and weigh it with the mass of barium sulphate then multiplying by 0.6086, namely is equivalent to
sodium sulfate (of Na2SO3) content.
Toxicity
ADI does not make restrictive regulations (FAO/WHO, 2001).
GRAS (FDA, §186. 1797, 2000).
LD50: 5989mg/kg (mice through oral administration).
Chemical Properties
It appears as white monoclinic crystal or powder. It can be dissolved in water with the aqueous
solution being alkaline. IT can be dissolved in glycerol and is insoluble in ethanol.
Uses
It can be mainly used as the filler of synthetic detergent. Paper industry applies it for the cooking
agent during the manufacture of sulfate pulp. Glass industry uses it as substitute of soda. Chemical
industry applies it as the raw material for the manufacturing of sodium sulfide, sodium silicate and
other chemical products. Textile industry applies it for the formulation of Vinylon spinning coagulation
bath. The pharmaceutical industry applies it as laxatives. It can also be used in non-ferrous
metallurgy and leather.
Production method
Vacuum evaporation method: clarify the natural Glauber's salt after dissolving it; put the clarified
solution for vacuum evaporation dehydration, thickening, centrifugation and separation and drying to
obtain anhydrous sodium sulfate. The reaction equation is: Na2SO4·10H2O → Na2SO4 + 10H2O
Calcium mirabilite method: crush the ore of calcium mirabilite, add water ball for grinding, leach, with
the leached Glauber's salt being subject to removal of impurities via filtering out. After the
clarification of the filtrate, then perform evaporation for dehydration, centrifugation, drying to obtain
the anhydrous sodium sulfate. The reaction is:
Na2SO4·CaSO4 + 2H2O → Na2SO4 + CaSO4·2H2O
Conversion method uses the byproduct, high and low-temperature salt produced from potassium
chloride as the raw material for making anhydrous sodium sulfate. Under certain conditions of
temperature and ingredients, through three sections of transformation, magnesium sulfate and
sodium chloride have been first converted into bloedite and then further converted to anhydrous
sodium magnesium sulfate and finally being converted to anhydrous sodium sulfate. The entire
conversion process is a continuous countercurrent operation with pulp relying the mechanical driving
and elevation, liquid undergoing reverse overflow via potential difference. The conversion of the first
segment is controlled at Ph value of 3 to 4 with reaction at a temperature of 55~70 ℃. The generated
white sodium magnesium alumina slurry, after entering into a settler for thickening and then sent to
the secondary conversion tank; secondary conversion has Ph of 4~5 and temperature of about 100
℃; third conversion conditions is controlled at Ph5~6 with the temperature being about 55 ℃. Under
stirring, the anhydrous loeweite can react with an aqueous solution of sodium chloride to generate
anhydrous sodium sulfate crude product with centrifuge, separation, drying to obtain the anhydrous
sodium sulfate to obtain. The reaction equation is:
2NaCl + 2MgSO4 + 4H2O → Na2SO4·MgSO4·4H2O + MgC12
Na2SO4·MgSO4·4H20 → Na2SO4·MgSO4 + 4H2O
Na2SO4·MgSO4 + 2NaCl → 2Na2SO4 + MgCl2
This method has high cost, low recycling rate with sulfuric acid consumption and the impurities not
being prone to be removed. The resulting product is of poor color, but with simple equipment. Rayon
byproduct method: the rayon solidification waste undergoes crystallization, dissolution,
neutralization, filtration, concentration, cooling, separation and drying process to obtain anhydrous
sodium sulfate. The reaction equation is:
H2SO4 + 2NaOH → Na2SO4 + 2H2O