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J.

Rodricks January 5, 2013

Some terms relating to safety

Hazard = the type of harm to health a chemical or other agent can cause (cancer, allergy,
liver disease, vomiting, etc.)

Risk = the likelihood, or probability, that the chemical or other agent will cause that harm
under the conditions of exposure people actually experience.

Risk Assessment = the scientific analysis used to understand risk in specific


circumstances.

Risk Management = actions taken to control risks.

Safety is said to have been achieved when risks have been adequately controlled.

How do we learn about an agent’s hazards?

1) We conduct epidemiology studies in populations exposed to the agent.

2) We expose animals to the agent in an experimental setting.

Animal studies are generally accepted as sufficiently reliable predictors of toxicity


hazards in humans for use in regulatory and public health decisions.

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