Professional Documents
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GLP Handbook
GLP Handbook
Machiavelli
Hazardous Material in BIOTECH
Environmental Protection
Environmental Protection Agency (EPA) has
primary responsibility for enforcement of
laws to prevent environmental contamination
with hazardous chemicals.
Clean Water Act
Safe Drinking Water Act
Clean Air Act
Environmental Protection
Resource Conservation and Recovery Act (RCRA)
Provides a system for tracking hazardous waste,
including poisonous or reactive chemicals from
creation to disposal (cradle to grave)
Laboratory Responsibility
Institutions have policies, but these
policies need to be implemented at the
individual laboratory level.
Housekeeping
Clean Up after yourself!
Balances, Centrifuges, other common
equipment.
Freezers and Refrigerators
Laboratory Responsibility
Emergency Response
All Personnel should be familiar with basic emergency
responses.
At least one person trained in CPR and basic first aid
First aid kit must be readily accessible and fully
stocked
All required protective devices such as fire
extinguishers, fire blankets, and eyewash stations
must be well marked and easily accessible.
Emergency telephone numbers and instructions
should be prominently displayed b y each phone
Evacuation routes should be kept well clear of boxes
and clutter.
Laboratory Responsibility
Laboratory Rooms should be labeled
Hazard Diamond System: rates chemicals
according to their fire, reactivity, and general
health hazards
Scale of 0-4; 0 being non-hazardous, 4 being
very hazardous
Biosafety Levels
Personnel Responsibility
Personnel Responsibility
Flammable Chemicals
Reactive Chemicals
Corrosive Chemicals
Toxic Chemicals
Controlling the Exposure
Can you replace the substance
Animal carcasses
RISK PHRASES
R45 – CARCINOGENIC
R46 – HERITABLE GENETIC DAMAGE
R20/21/22 – HARMFUL IN CONTACT/ INHALE
R25 – HARMFUL IF SWALLOWED
R35/36 – IRRITATE EYE/SKIN
R43 – SKIN SENSITIZATION
R48/23/24 – TOXIC IN INHALE/CONTACT
R62 – IMPAIRED INFERTILITY
LABEL
Risk assessment
Risk Assessment for Biological Agents