DRUG ACTION INDICATION CONTRAINDICATION ADVERSE EFFECT NURSING

RESPONSIBILITIES
Magnesium Sulfate

Classification: > Depresses CNS, > MgSO4 is indicated Concentrations CNS: Weakness, Before:
Antacid, blocks peripheral for immediate - Allergy to drowsiness, > Monitor knee-jerk
anticonvulsant, neuromuscular control of life- magnesium products dizziness, fainting, reflex.
electrolyte, laxative. transmission, threatening - Myocardial damage sweating > Monitor respiratory
produces convulsions in the - 2hr preceding rate.
Dosage: anticonvulsant treatment of severe delivery Respiratory: > Monitor urine
> 5 gms IVP as stat effects; decreases toxemias (pre- Decreased output.
dose amount of eclampsia and Precaution respiratory rate
> 5 gms deep IM acetylcholine eclampsia) of - Renal insufficiency During:
each buttocks as stat released at end-plate pregnancy. CV: Palpitations > Observe 12 R’s in
dose by motor nerve giving meds
impulse. Metabolic: > Assess for injection
> Prevention of Magnesium site
seizures in severe intoxication, > Give IM route by
preeclampsia hypocalcemia with deep IM injection.
tetany.
After:
> Monitor urine
output
> Monitor respiratory
rate or breathing
difficulties
> Report sweating,
flushing, muscle
tremors or twitching,
inability to move
extremities.
> Maintain urine
output at a level of
<30 mL every 1hr
 DRUG ACTION INDICATION CONTRAINDICATION ADVERSE EFFECT NURSING
RESPONSIBILITIES
Hydralazine

Classification: > Direct vasodilating General Indications Concentrations CNS: Before:

Vasodilator; effects on arterioles. > Hypertension - Hypersensitivity to Headache, peripheral - Check blood
Antihypertensive Therapeutic Effect: > Eclampsia CAD, mitral valvular neuritis, dizziness, pressure.
Decreases B/P, rheumatic heart tremors, psychotic - Assess bowel
Dosage: systemic vascular disease reactions, sounds.
> 5 mg IVP as stat resistance. characterized by - Assess voiding
dose Precaution depression, pattern.
- with CAD’s disorientation,
- increased intracranial anxiety During:
pressure - Observe the 12 R’s
- advanced renal CV: in giving meds
damage Palpitations, - If there’s changes in
- pulmonary tachycardia, angina color of the
hypertension pectoris, medication, do not
hypotension, give and discard it
paradoxical pressor
response, orthostatic After:
hypotension - Monitor for
orthostatic
GI: hypotension.
Anorexia, nausea, - Report persistent or
vomiting, diarrhea, severe constipation,
constipation, unexplained fever or
paralytic ileus malaise, muscle or
joint aching, chest
Hematologic: pain, rash,
Hypersensitivity: numbness, tingling
Rash, urticaria,
pruritus, fever, chills,
arthralgia,
eosinophilia; rarely,
hepatitis, obstructive
jaundice