Professional Documents
Culture Documents
Practice Test 4
Practice Test 4
MCAT
Practice Test 4-CBT
i b ut e
D is t r
N ot
Do
1 of 62
Non-Disclosure Statement
for the
In consideration of being permitted to take this practice test, I affirm that I am bound on my honor to take
the practice test without sharing the content in any form including, printed, electronic, voice, or other means. I
further affirm that I understand that my scores on this practice test are an estimate of the scores I may achieve
t e
on the actual MCAT. I understand that if the AAMC has reason to believe that I have violated this non-
u
disclosure statement, it may, at its discretion, bar me from future practice tests and/or examinations, or take
other appropriate actions.
i b
D is t r
By downloading, printing, or taking this practice test, I acknowledge that I have read this non-
disclosure statement and agree to abide by the terms stated therein.
N ot
Do
2 of 62
If you started a practice test online, the answer sheet provided at the end of this printout does not include
the answers you entered online. Your online answers will appear on the online answer sheet used to
submit your answers for scoring.
Once you have completed your offline practice test, follow these steps to enter your answers and
submit them for scoring.
Login to the web site.
If this is a new test, click the "Start on Paper" link provided in the "Start a New Test"
table of your home page.
If you want to continue entering answers for an in-progress test, click the "Restart on
Paper" link provided in the "In-Progress Tests" table of your home page.
Click the "Ready to Enter Your Answers? Click Here" link.
Enter your answers in the provided form. Any answers previously entered using your
online practice test or this answer sheet will appear in the form.
Once you have finished entering your answers be sure to save them by clicking "Save",
"Save and Exit", or "Review Online". If you close the answer sheet page without
t e
clicking one of these links, your answers will not be saved.
u
You may return to the answer sheet to enter or review answers as many times as you like.
i b
When you are ready to submit your final answers for scoring, click the "Mark as
D i t r
Complete" link. Once you submit your final answers for scoring, you will not be able to
s
review or modify your answers using the entry form.
After your answers have been submitted for scoring, you will automatically return to your
N
Tests" table.
t
home page. To view your diagnostic score report, click the provided in the "Completed
o
From the diagnostic score report you can review your answers and the solution for each
Do
question.
3 of 62
Printing Guide
To print, click the PRINTER icon located along the top of the window and enter one of the
following options in the PRINT RANGE section of the print dialog window:
r
Writing Sample Section
t
enter pages 39 to 41
o
Biological Sciences Section
enter pages 42 to 61
Do N Periodic Table
Click PAGES FROM radio button and
enter page 6
This document has been encoded to link this download to your member account. The AAMC and its
Section for the MCAT hold the copyrights to the content of this Practice Test. Therefore, there can be no
sharing or reproduction of materials from the Practice Test in any form (electronic, voice, or other
means). If there are any questions about the use of the material in the Practice Test, please contact the
MCAT Information Line (202-828-0690).
4 of 62
Physical Sciences
Time: 70 minutes
Questions: 1-52
Most questions in the Physical Sciences test are organized into groups, each containing a descriptive passage.
After studying the passage, select the one best answer to each question in the group. Some questions are not
based on a descriptive passage and are also independent of each other. If you are not certain of an answer,
eliminate the alternatives that you know to be incorrect and then select an answer from the remaining
alternatives. Indicate your selected answer by marking the corresponding answer on your answer sheet. A
periodic table is provided for your use. You may consult it whenever you wish.
i b ut e
D is t r
N ot
Do
This document has been encoded to link this download to your member account. The AAMC
and its Section for the MCAT hold the copyrights to the content of this Practice Test. Therefore,
there can be no sharing or reproduction of materials from the Practice Test in any form
(electronic, voice, or other means). If there are any questions about the use of the material in the
Practice Test, please contact the MCAT Information Line (202-828-0690).
5 of 62
1 2
Periodic Table of the Elements
H He
1.0 4.0
3 4 5 6 7 8 9 10
Li Be B C N O F Ne
6.9 9.0 10.8 12.0 14.0 16.0 19.0 20.2
11 12 13 14 15 16 17 18
Na Mg Al Si P S Cl Ar
23.0 24.3 27.0 28.1 31.0 32.1 35.5 39.9
19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36
K Ca Sc Ti V Cr Mn Fe Co Ni Cu Zn Ga Ge As Se Br Kr
39.1 40.1 45.0 47.9 50.9 52.0 54.9 55.8 58.9 58.7 63.5 65.4 69.7 72.6 74.9 79.0 79.9 83.8
37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54
Rb Sr Y Zr Nb Mo Tc Ru Rh Pd Ag Cd In Sn Sb Te I Xe
85.5 87.6 88.9 91.2 92.9 95.9 (98) 101.1 102.9 106.4 107.9 112.4 114.8 118.7 121.8 127.6 126.9 131.3
55 56 57 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86
Cs Ba La* Hf Ta W Re Os Ir Pt Au Hg Tl Pb Bi Po At Rn
132.9 137.3 138.9 178.5 180.9 183.9 186.2 190.2 192.2 195.1 197.0 200.6 204.4 207.2 209.0 (209) (210) (222)
87 88 89 104 105 106 107 108 109 110 111 112 114 116
Fr Ra Ac† Rf Db Sg Bh Hs Mt Ds Uuu Uub Uuq Uuh
(223) (226) (227) (261) (262) (266) (264) (277) (268) (281) (272) (285) (289) (289)
58
* Ce
140.1
59
Pr
140.9
60
Nd
144.2
61
Pm
i
(145)
b ut
Sm
e
62
150.4
63
Eu
152.0
64
Gd
157.3
65
Tb
158.9
66
Dy
162.5
67
Ho
164.9
68
Er
167.3
69
Tm
168.9
70
Yb
173.0
71
Lu
175.0
r
90 91 92 93 94 95 96 97 98 99 100 101 102 103
† Th
232.0
Pa
(231)
U
238.0
D is t
Np
(237)
Pu
(244)
Am
(243)
Cm
(247)
Bk
(247)
Cf
(251)
Es
(252)
Fm
(257)
Md
(258)
No
(259)
Lr
(260)
N ot
Do
6 of 62
Do
A) Static friction is independent of base area.
B) Static friction is directly proportional to base area.
C) Static friction is directly proportional to the square
of base area.
D) Static friction is inversely proportional to base
area.
Sharing or reproducing this material in any form is a violation of the AAMC copyright Page 7 of 62
4. After a block began to slide, how did its speed 5. The researchers devised a second procedure to
vary with time? (Note: Assume that the tension measure static friction. They removed the string
and kinetic friction forces on the block were from a block, placed the block at rest on a board,
constant in magnitude.) and raised one end of the board until the block
began to slide. To determine the static friction
A) It was constant in time.
force on the block when sliding began, which of
B) It increased exponentially with time. the following measurements did they make?
C) It was first constant, then increased linearly with A) Time it took for the block to slide down the board
time.
B) Distance the block slid down the board before
D) It increased linearly with time. coming to rest
C) Mass of the board
D) Angle of the board with respect to the horizontal
i b ut e
D is t r
N ot
Do
Sharing or reproducing this material in any form is a violation of the AAMC copyright Page 8 of 62
e
NH3 is prepared commercially by the reaction of N2
with H2 (Reaction IV). NH3 has a tendency to form
coordination compounds, such as [Co(NH3)6]Cl3, in
which NH3 forms covalent bonds with a transition
D is t
ΔH = –92 kJ/mol
A) Addition of H2
B) A decrease in pressure
N
Reaction IV
ot C) An increase in temperature
D) Addition of a catalyst
Do
N2 and O2 are both prepared by the fractional
distillation of air. Air samples are first condensed to
the liquid state and then passed through a distilling 9. If 36 g of S and 32 g of O2 were used in Reaction
column. The N2 separates first, and then the O2 is I, which of the following would be the limiting
obtained. reagent?
A) S
B) O2
C) SO2
D) There would not be a limiting reagent.
Sharing or reproducing this material in any form is a violation of the AAMC copyright Page 9 of 62
The wavelength of a radio wave measured by a The frequency of the transmitted radio signal was
stationary receiver differs from the emitted kept constant at 2.0 x 106 Hz, and the transmitted
wavelength when the transmitter is moving. The wavelength was kept constant at 150 m as the jet flew
frequency measured by the receiver also changes directly away from the receiver at the four different
when the transmitter is moving. Three experiments speeds listed in Table 2.
were conducted to determine relationships between
the speed of a moving radio transmitter and the Table 2 Constant Transmitted f and λ with Different
changes in wavelength and frequency measured at the Jet Speeds Away from Receiver
receiver. In each of the experiments, a jet flew at
constant altitude and emitted a signal that was Change in
measured by a receiver on the ground. Speed Change in f λ
(m/s) (Hz) (10–5m)
Experiment 1 246 –1.64 12
322 –2.15 16
The jet flew directly away from the receiver at 268 447 –2.98 22
m/s. Signals with different frequencies (f) and 671 –4.47 34
wavelengths (λ) were transmitted in four trials. The
transmitted frequencies and wavelengths are listed in
Table 1 along with the measured changes in
frequency and wavelength.
i b ut e Experiment 3
N 6
f
(10 Hz)
Change
in f
(Hz)
λ
(m)
ot Change
in λ
(10–5m)
Table 3 Constant Transmitted f and λ with Different
Jet Speeds toward Receiver
Do
1.20 –1.07 250 22 Speed Change in f Change in λ
1.50 –1.34 200 18 (m/s) (Hz) (10–5m)
2.00 –1.79 150 13 300 2.00 –15
3.00 –2.68 100 9 490 3.27 –24
Sharing or reproducing this material in any form is a violation of the AAMC copyright Page 10 of 62
10. A stationary receiver detects a change in 11. Which of the following graphs best illustrates the
frequency of the signal from a jet flying directly relationship between speed of the transmitter
away from it at 300 m/s. Which of the following away from the receiver and the increase in
receivers will detect the same change in wavelength of the received signal?
frequency from a jet moving away at 600 m/s? A)
A) A receiver moving at 900 m/s in the opposite
direction as the jet
B) A receiver moving at 300 m/s in the opposite
direction as the jet
C) A stationary receiver
D) A receiver moving at 300 m/s in the same
direction as the jet B)
i b ut e C)
D is t r
N ot D)
Do
12. As the speed of the jet flying away from the
receiver increases, what happens to the distance
between adjacent peaks of the transmitted waves,
as measured at the receiver?
A) It decreases.
B) It remains constant.
C) It increases.
D) It changes, but is not dependent on the speed.
Sharing or reproducing this material in any form is a violation of the AAMC copyright Page 11 of 62
13. Why are the percentages of the change in 15. An astronomer observes a hydrogen line in the
frequency and wavelength much greater when spectrum of a star. The wavelength of hydrogen
sound waves are used instead of radio waves in in the laboratory is 6.563 x 10-7m, but the
these experiments? wavelength in the star’s light is measured at
6.56186 x 10-7m. Which of the following
A) Sound waves travel more slowly.
explains this discrepancy?
B) Sound waves have a much higher frequency.
A) The star is moving away from Earth.
C) Sound waves have a much shorter wavelength.
B) The wavelength of light that the star is emitting
D) Interference in the atmosphere affects sound changes constantly.
waves much more.
C) The frequency of light that the star is emitting
changes constantly.
14. A receiver is in a jet flying alongside another jet
that is emitting 2.0 x 106 Hz radio waves. If the D) The star is approaching Earth.
jets fly at 268 m/s, what is the change in
frequency detected at the receiver?
A) 0 Hz
B) 0.90 Hz
C) 1.79 Hz
D) 3.58 Hz
i b ut e
D is t r
N ot
Do
Sharing or reproducing this material in any form is a violation of the AAMC copyright Page 12 of 62
These questions are not based on a descriptive 18. An object with 15 grams mass is immersed in
passage and are independent of each other. benzene and suffers an apparent loss of mass of 5
grams. What is the approximate specific gravity
16. An aqueous solution of a salt made by mixing of the object? (Data: Specific gravity of benzene
which of the following acids and bases displays = 0.7)
the lowest pH? A) 1.4
A) Strong acid, weak base B) 1.8
B) Strong acid, strong base C) 2.1
C) Weak acid, weak base D) 3.0
D) Weak acid, strong base
19. A student has a thin copper beaker containing
17. Depth (cm) Pressure (N/m2) 100 g of a pure metal in the solid state. The metal
5 250 is at 215oC, its exact melting temperature. If the
10 450 student lights a Bunsen burner and holds it for a
15 650 fraction of a second under the beaker, what will
happen to the metal?
The table above gives pressure measured at A) A small amount of the metal will turn to liquid,
various depths below the surface of a liquid in a with the temperature remaining the same.
container. A second liquid, whose density is
twice that of the first liquid, is poured into a
second container. Similar pressure measurements
D
the pressure at a depth of 10 cm for the second
t
liquid? will increase slightly.
A) 250 N/m2
N o
Do
B) 450 N/m2
C) 850 N/m2
D) 1650 N/m2
Sharing or reproducing this material in any form is a violation of the AAMC copyright Page 13 of 62
r
H2O(ℓ)
D is t Equation 3
N ot students.
Do Mass KHP
Moles KHP
Vol NaOH
vs KHP
A
0.5500
g
0.002752
25.02
mL
B
25.20
mL
C D E
Sharing or reproducing this material in any form is a violation of the AAMC copyright Page 14 of 62
20. How many moles of KHP are present in the 24. What is the conjugate base of chlorobenzoic
sample of KHP of student A? acid?
A) 2.752 x 10-1 mol A) OH-
B) 2.693 x 10-2 mol B) H2O
C) 2.693 x 10-3 mol C) C7H4ClO-
D) 3.712 x 102 mol D) C7H4ClO2-
21. Which of the following changes in state functions 25. Student E accounted for the equivalent weight
occurred during the dissolution shown in found for succinic acid by analyzing its titration
Equation 1? with NaOH(aq) and concluding that it is:
I. ΔH < 0 A) diprotic and requires one-half the number of moles
II. ΔG > 0
of NaOH expected for a monoprotic acid.
III. ΔS > 0
B) diprotic and requires twice the number of moles of
A) I only NaOH expected for a monoprotic acid.
B) II only C) triprotic and requires one-third the number of
C) I and III only moles of NaOH expected for a monoprotic acid.
D) II and III only D) triprotic and requires three times the number of
t
NaOH(aq) would be:
C) 0.4 M
N
D) 4.0 M
o A) too high because the actual number of moles of
KHP titrated would be less than the number used
Do
in the calculations.
23. At the stoichiometric (equivalence) point in a B) too low because the actual number of moles of
titration of benzoic acid with NaOH(aq) shown KHP titrated would be more than the number used
by Equation 3, the pH is: in the calculations.
A) < 4. C) too low because the actual number of moles of
KHP titrated would be less than the number used
B) > 4 and < 7. in the calculations.
C) = 7. D) unaffected because the weighed KHP was
D) > 7. dissolved in water, making any moisture in the
sample unimportant.
Sharing or reproducing this material in any form is a violation of the AAMC copyright Page 15 of 62
i b ut e
r
Property Value
density
solute conc.
1.1326 kg/L
226.5 g/L
t
molarity 2.241 mol/L compounds is added to a saturated solution of
o
water conc. 906.1 g/L KNO3(aq) EXCEPT:
N
g H2O displaced A) NH4NO3(s).
Do
by solute 92.2 g/L
condosity 2.49 mol/L B) Ca(NO3)2(s).
C) NH4Cl(s).
The condosity of a solution is defined as the molar
D) KCl(s).
concentration of sodium chloride that has the same
specific conductance (electrical) as the solution.
Sharing or reproducing this material in any form is a violation of the AAMC copyright Page 16 of 62
29. Which point on the condosity plot shown below 30. How many grams KNO3 are in 100 mL of the
represents the student-prepared solution of student-prepared solution of KNO3(aq)?
KNO3(aq), if the point labeled NaCl represents A) 11.33 g
2.49 M NaCl(aq)?
B) 22.41 g
C) 22.65 g
D) 34.00 g
i b ut e
D is t r
N ot
Do
Sharing or reproducing this material in any form is a violation of the AAMC copyright Page 17 of 62
These questions are not based on a descriptive 34. The fundamental, resonant wavelength of a pipe
passage and are independent of each other. open at both ends that is 1 m long and 0.1 m in
diameter is:
32. Suppose that CH4(g) reacts completely with A) 0.1 m.
O2(g) to form CO2(g) and H2O(g) with a total
pressure of 1.2 torr. What is the partial pressure B) 0.2 m.
of H2O(g)? C) 1.0 m.
A) 0.4 torr D) 2.0 m.
B) 0.6 torr
C) 0.8 torr 35. Mechanical waves in a medium such as water
function to transport:
D) 1.2 torr
A) matter only.
33. A compound was analyzed and found to contain B) energy only.
12.0 g carbon, 2.0 g hydrogen, and 16.0 g C) both matter and energy.
oxygen. What is the empirical formula for this
compound? D) neither matter nor energy.
A) CH2O
e
B) C6HO8
C) C6H12O6
D) C12H2O16
ri b ut
D is t
N ot
Do
Sharing or reproducing this material in any form is a violation of the AAMC copyright Page 18 of 62
i b ut e D) m1v1/m2 + m2v2/m1.
r
surface. Using this simplified model and modern 39. What kind of object is emitted in the decay of
measurements of continent drift speeds and positions,
one determines that the continents should have
collided 120 million years ago, a significantly more
D is t 40
K?
A) A gamma ray
recent time than evidence from the scene would
suggest.
N ot B) An alpha particle
C) An electron
Do
36. Which of the following quantities was necessarily D) A positron
conserved in the collision of the model
continents? 40. A continent of mass m collides with a continent
A) Momentum of mass m/2 that is initially at rest. During the
collision, the more massive continent is found to
B) Kinetic energy exert a force F on the less massive continent,
C) Potential energy causing the smaller continent to accelerate. At the
same time, the less massive continent exerts a
D) Impulse
force on the larger continent of magnitude:
A) F/2.
B) F.
C) 2F.
D) 0.
Sharing or reproducing this material in any form is a violation of the AAMC copyright Page 19 of 62
Passage VII 41. Which of the following changes to the circuit will
decrease the electric field between the electrodes
A vacuum photodiode detector utilizes the by the greatest amount?
photoelectric effect to detect light. The photoelectric
effect causes electrons to be ejected from a metal A) Increasing L by a factor of 2
plate when photons of light are absorbed by the metal. B) Decreasing L by a factor of 2
The energy of a photon is given by the equation E =
C) Increasing R by a factor of 2
hf, where h = 6.6 x 10-34J·s (Planck’s constant), and f
is the frequency of the photon. To free an electron, D) Decreasing R by a factor of 2
the energy of a photon must be greater than a quantity
called the work function of the metal. The ejected 42. An electron is ejected from the cathode by a
electron will have a kinetic energy equal to the photon with an energy slightly greater than the
photon’s energy minus the work function. work function of the cathode. How will the final
kinetic energy of the electron upon reaching the
A vacuum photodiode is constructed by sealing two anode compare to its initial potential energy
electrodes, a cathode and an anode, in a vacuum tube. immediately after it has been ejected?
The electrodes are separated by a distance, L = 0.01
m, and connected to a battery and a resistor, R = 100 A) It will be 2 times as large.
Ω, as shown in Figure 1. The cathode is made of a B) It will be approximately equal.
photoelectric metal and is connected to the negative
C) It will be 1/4 as large.
terminal of the battery. The potential difference
between the cathode and anode is approximately
equal to the battery voltage, V = 50 V. The electric
i b ut e D) It will be 0.
r
field at all points between the electrodes is equal to 43. When the number of photons incident on the
the electrode voltage difference divided by L. The
D
released from the cathode is equal to qV, where q = -
i
potential energy of an electron immediately after it is
t
quantities also increases?
1.6 x 10-19C is the charge of an electron. The work
function for the vacuum photodiode is 2 x 10-19J.
Do
C) Magnitude of the electric field between the
electrodes
D) Speed of electrons at the anode
Sharing or reproducing this material in any form is a violation of the AAMC copyright Page 20 of 62
i b ut e
D is t r
N ot
Do
Sharing or reproducing this material in any form is a violation of the AAMC copyright Page 21 of 62
These questions are not based on a descriptive 51. Suppose a certain far-sighted person can see
passage and are independent of each other. objects clearly no closer than 300 cm away. What
is the minimum distance from a plane mirror such
48. In the Bohr model of the atom, radiation is a person must be to see his reflection clearly?
emitted whenever electrons: A) 75 cm
A) change orbits. B) 150 cm
B) undergo acceleration. C) 300 cm
C) move to orbits of lower energy. D) 600 cm
D) move to orbits of larger radius.
52. A solution of H2SO4(aq) has a pH of 6.0. What is
49. Which of the following phase changes is used to the H3O+(aq) concentration?
determine the heat of fusion for a pure substance?
A) 1 x 106
A) Melting of a solid
B) 5 x 10-7
B) Sublimation of a solid C) 2 x 10-6
C) Boiling of a liquid D) 1 x 10-6
D) Condensation of a gas
50.
i b ut e
D is t r
N ot
Do
In the circuit shown above, the current in the 2-
ohm resistance is 2 A. What is the current in the
3-ohm resistance?
A) 2 A
B) 3 A
C) 4 A
D) 6 A
Sharing or reproducing this material in any form is a violation of the AAMC copyright Page 22 of 62
Verbal Reasoning
Time: 60 minutes
Questions: 53-92
There are seven passages in the complete Verbal Reasoning test. Each passage is
followed by several questions. After reading a passage, select the one best answer to
each question. If you are not certain of an answer, eliminate the alternatives that you
know to be incorrect and then select an answer from the remaining alternatives. Indicate
your selected answer by marking the corresponding answer on your answer sheet.
i b ut e
D is t r
N ot
Do
This document has been encoded to link this download to your member account. The
AAMC and its Section for the MCAT hold the copyrights to the content of this
Practice Test. Therefore, there can be no sharing or reproduction of materials from the
Practice Test in any form (electronic, voice, or other means). If there are any questions
about the use of the material in the Practice Test, please contact the MCAT
Information Line (202-828-0690).
23 of 62
r
leaders. This new approach found expression in the Material used in this test passage has been adapted from the
United Nations Charter and, more specifically, in the
Universal Declaration of Human Rights, approved
without a dissenting voice in December 1948. The
D is t following source:
W. Laquer and B. Rubin, eds., The Human Rights
Reader. ©1989 by W. Laquer and B. Rubin.
ot
president of the General Assembly, Dr. H. V. Evatt of
Australia, said at the time that this was the first
N
occasion on which the organized world community
53. According to the passage, when judging the
human rights record of a country, one must take
Do
had recognized the existence of human rights and into account:
fundamental freedoms transcending the laws of I. the country’s level of development.
sovereign states. II. the country’s social and cultural
circumstances.
But although millions of men and women have indeed III. whether the country is moving toward or
turned to the Universal Declaration of Human Rights, away from greater human rights.
they have received very little guidance and no help A) II only
from the organization that propagated it. The failure
of the United Nations to live up to early expectations B) III only
and to become an effective instrument for the C) I and II only
promotion of human rights has induced individual
governments and nongovernmental bodies to take D) I, II, and III
fresh initiatives in this area. In 1947, the Organization
of American States passed a declaration on the rights
and duties of humankind; in 1950, the Council of
Europe agreed on a covenant for the protection of
human rights and fundamental freedoms and
established the European Commission for Human
Sharing or reproducing this material in any form is a violation of the AAMC copyright Page 24 of 62
54. Regarding the concept of human rights, the 57. On the sole basis of the passage, determine which
author asserts that non-Western cultures: of the following acts the author would most want
to see forbidden by international law, regardless
A) originated the concept of human rights.
of the level of development of the country in
B) understood human rights before being exposed to which it takes place.
Western cultures.
A) Using private property for state purposes
C) initially resisted the concept of human rights
B) Placing certain conditions on the right to vote
introduced by Western cultures.
C) Suspending certain freedoms in times of national
D) developed explicit covenants about human rights
emergency
before Western cultures did so.
D) Torturing political dissidents
55. The U.S. Declaration of Independence and the
French Declaration of the Rights of Man and 58. Which of the following statements most strongly
Citizen are cited in the passage as evidence that: challenges one of the assertions made in the
passage?
A) the concept of human rights was not alien to early
non-Western cultures. A) The citizens of any country have the right to
disobey unjust laws.
B) the English Bill of Rights was not the only early
document that promoted human rights. B) Countries have the right to manage their own
internal affairs without outside interference.
C) throughout the last century, it was commonly held
that international law applied only to states.
r
D) the issue of human rights has been prominent in
world thinking for centuries.
t
56. The passage implies that an underdeveloped
o
country that replaces a repressive dictator with a
N
democratic leader sworn to oppose the
Do
persecution of the country’s citizens should be:
A) praised cautiously for its first steps at moving
away from human rights abuses.
B) monitored intensely for possible human rights
abuses.
C) forgiven its past persecutions due to the poor
condition of its economy.
D) criticized harshly for not having instituted
democratic reforms sooner.
Sharing or reproducing this material in any form is a violation of the AAMC copyright Page 25 of 62
e
That is the voice of the “woman writer.” But it is a
of condition and temperament do not apply, or at least
not much, and that all writing women possess – not
by virtue of being writers but by virtue of being
N ot
I deny this. There is a human component to literature
that does not separate writers by sex but that – on the
writer or writer, and all the writers will be expected to
be male – an uninspiring social and literary
atmosphere the world has known before.
Do
contrary – engenders sympathies from sex to sex,
from condition to condition, from experience to Material used in this test passage has been adapted from the
experience, from like to like, and from unlike to following source:
unlike. Literature universalizes. Without disparaging C. Ozick, Art & Ardor: Essays. ©1983 by C. Ozick.
particularity or identity, it universalizes; it does not
divide. 59. According to the passage, women writers say
they will end their voluntary segregation when:
Does a “woman writer” have a body of separate A) women writers gain sufficient political power.
experience by virtue of being a woman? It was this
B) literature recognizes humanity-as-a-whole.
myth-fed condition of segregation that classical
feminism was created to bring to an end. Insofar as C) women writers’ imaginations are set free.
some women, and some writers who are women, have D) a new generation of women writers appears.
separate bodies of experience or separate
psychologies, to that degree has the feminism of these
women not yet asserted itself. In art, feminism is that
idea which opposes segregation; which means to
abolish mythological divisions; which declares that
Sharing or reproducing this material in any form is a violation of the AAMC copyright Page 26 of 62
60. The author of the passage states that in the arts, 63. If the author of the passage admired the fiction or
feminism is a force that: poetry of one of the self-labeled women writers,
this admiration would be most discrepant with
A) gives women writers an instantly perceived
the passage assertion that:
common ground.
A) classical feminism was created to bring an end to
B) opposes segregation and mythological divisions.
intellectual segregation.
C) groups writers into two categories.
B) women writers believe that they can be nourished
D) helps women writers to accept humanity-as-a- only by other women writers.
whole.
C) a world in which all writers are men would be
uninspiring.
61. The passage indicates that its author would NOT
agree with which of the following statements? D) an imagining writer should not use the language of
politics.
A) Because women have different life experiences
than do men, each sex must develop its own
values. 64. Which of the following works would the author
of the passage be most likely to describe as
B) Women who write should feel free to express their literature?
political viewpoints.
A) A play in which men’s and women’s lives are
C) Literature can help men and women to become treated sympathetically
more sympathetic toward one another.
D) Women should earn the same wages as men.
N
B) these women will become political.
ot should be a woman
Do
C) the human component of literature will disappear.
D) only male writers will be called writers.
Sharing or reproducing this material in any form is a violation of the AAMC copyright Page 27 of 62
r
confidentiality is particularly important in a prison discovered during a routine examination, the prisoner
hospital setting, in which patients feel distrust
because physicians are often employed by the
incarcerating institution.
N ot
prison setting is essential for good medical practice.
taken to remove it. If Prisoner A is harboring drugs
and a needle, drug use is quite possibly contributing
to A’s health problem. It is the physician’s
Do
Physicians working in prisons also retain the privilege responsibility to educate A about the potential harm
of confidential interactions with patients, although the of drug use.
prison authorities may try to pressure doctors to
supply information. Even if physicians are employed Material used in this test passage has been adapted from the
by the prison, their first responsibility is to their following source:
C. Levine (Ed.), Cases in Bioethics: Selections from the
patients. The circumstances in which to give Hastings Center Report. ©1989 by St. Martin's Press.
privileged information to prison authorities remains
the physician’s decision.
Sharing or reproducing this material in any form is a violation of the AAMC copyright Page 28 of 62
65. Assume that a prison did not have a policy of 67. The author argues that a routine examination is
obtaining informed consent before a diagnostic part of the confidential communication between a
procedure, and almost all of the inmates refused patient and a physician and that the clinical
to be X-rayed. The author’s comments suggest autonomy of the physician is essential for good
that this situation could reasonably be interpreted medical practice in prisons. These beliefs imply
as evidence that prisoners: that:
A) believe that they have a Constitutional right to A) if the quality of medicine practiced in a prison
privacy. declines, a physician has violated the
confidentiality of a routine examination.
B) are less concerned about their health than are
nonprisoners. B) if all physicians in a prison refuse to reveal
information about prisoners obtained during
C) distrust physicians who are employed by the
routine examinations, the physicians in that prison
prison.
have clinical autonomy.
D) feel a need to carry weapons for self-protection.
C) if all physicians who conduct routine examinations
in a prison respect their patients’ confidence, the
66. Suppose that a prisoner under sedation for a quality of medicine practiced in the prison is high.
medical procedure inadvertently reveals that a
weapon is hidden in the prisoner’s cell. Passage D) if a physician is required to reveal information
information suggests that the author would be about a prisoner obtained during a routine
examination, the quality of medicine practiced in
e
most likely to advise the physician to report the
incident:
A) only if the prisoner threatened to use the weapon.
t
68. With respect to prisoners, “necessary
s
B) only if the prisoner consented to the report. information” probably refers most specifically to
C) only if the prisoner subsequently denied that the
weapon existed.
D) regardless of the patient’s assertions.
ot D i a patient’s:
A) past criminal activities.
B) use of illegal drugs.
Sharing or reproducing this material in any form is a violation of the AAMC copyright Page 29 of 62
i b ut e
D is t r
N ot
Do
Sharing or reproducing this material in any form is a violation of the AAMC copyright Page 30 of 62
r
mechanism of evolution, how can altruism be part of intellectual history). If kin selection marks another
biology? Natural selection dictates that organisms act
in their own self-interest. They know nothing of such
abstract concepts as “the good of the species.” How,
N t
then, could anything but selfishness ever evolve as a
o Material used in this test passage has been adapted from the
following source:
Do
R. Lewin, In the Age of Mankind: A Smithsonian Book of
We owe the resolution of this paradox to the theory of Human Evolution. ©1988 by The Smithsonian Institution.
kin selection, which was developed in the early 1960s
by W. D. Hamilton, a British theoretical biologist.
71. The term unique overlay refers implicitly to our
According to this theory, animals evolve behaviors
human:
that endanger or sacrifice themselves only if such
altruistic acts increase their own genetic potential by A) altruistic behavior.
benefiting kin. Altruism and the society of kin must B) tendency toward animalistic behavior.
go hand in hand; the benefits of kin selection may
even propel the evolution of social interaction. C) propensity toward selfishness.
D) ability to be self-critical.
Kin selection seems to explain the key features of
social behavior in ants, bees, and wasps. But what can
it do for us? How can it help us to understand the
contradictory amalgam of impulses toward selfishness
and altruism that form our own personalities? I am
willing to admit – and this is only my intuition, since
we have no facts to constrain us – that kin selection
probably resolves Freud’s dilemma of the first
Sharing or reproducing this material in any form is a violation of the AAMC copyright Page 31 of 62
72. Which of the following assertions in the passage 75. It has been said that war is inevitable because
is NOT supported by an example or by reference brutality is a part of our biological heritage. The
to an authority? author would probably disagree by saying that:
A) “Free will” determines our behaviors within the A) we may be brutal by nature, but we are also kindly
wide range our genes permit. by nature.
B) The history of science has marked the continuous B) contrary to past beliefs, our true biological nature
retreat of humanity from center stage. is not brutal but altruistic.
C) Animals evolve altruistic behaviors only if such C) although our biological nature may be brutal, our
acts increase their own genetic potential. spirituality can help us to transcend this trait.
D) Successful civilization demands that we suppress D) biologically we may be brutal, but our human
our biological inclinations. ability to reason can help us to overcome this trait.
73. The author asks, “Yet if we accept the Darwinian 76. In another essay, the author quotes Benjamin
mechanism of evolution, how can altruism be Franklin as saying, “We must all hang together,
part of biology?” This question is most directly or assuredly we shall all hang separately.” This
dealt with in the author’s discussion of: quotation could best be used in the passage to
illustrate the survival value of:
A) natural selection.
A) biological determinism.
e
B) kin selection.
C) civilization.
D) evolution.
ri b ut B) reciprocal altruism.
C) animal aggression.
D is t D) genetic mutation.
t
may be nudged “toward a perception of respect 77. Freud’s argument that to behave altruistically we
o
and unity with other animals” because: must renounce many of our innate animalistic,
N
biological instincts is most weakened by which
A) we live at the hub of the universe and can
idea that is implicit in the passage?
Do
therefore see things with relative clarity.
A) Our tendency toward selfishness is directly linked
B) we are rational creatures and can therefore see the
to our animal ancestry.
importance of kindness toward other animals.
B) Darwin’s theory of natural selection dictates that
C) our behavior, like that of other animals, is entirely
an animal always acts in its own best interest.
governed by our genetic makeup.
C) Lower animals such as ants, wasps, and bees are
D) we see that our altruistic traits, like traits of other
capable of acts of self-sacrifice.
animals, may be due to biological evolution.
D) Human social life entails agonizing dilemmas.
Sharing or reproducing this material in any form is a violation of the AAMC copyright Page 32 of 62
Passage V The chance that the beetle would bring pollen to the
stigma would be increased if the male stamens were
The fossil record indicates that flowers originated in close proximity to the carpels. The stamens and
some time during the middle of the Mesozoic Era, carpels might even be advantageously grouped within
about 150 million years ago. Flowers probably made the same cone. The stamens would have to be present
their first humble appearance in the age of conifers, in large number so that they would not all be
cycads, dinosaurs, and beetles. Most of the seed- devoured by the beetles. In the course of time, the
bearing plants of that age were probably pollinated by outer stamens might become sterilized and pigmented
wind. They possessed the same kinds of reproductive and transformed into a set of showy petals. When
structures, including separate sexes and in some these conditions had been fulfilled, there would have
instances, winged pollen, that are associated with come into existence a structure possessing all the
wind pollination in their modern survivors. The essentials of a modern flower.
ovules were borne in cones or on leaves and exuded
drops of sap. When the bees, moths, butterflies, and long-tongued
flies arrived on the earth at the beginning of the
In the course of time, beetles feeding on the sap and Tertiary Period, some 70 million years ago, the
resin of stems and on leaves must have discovered evolution of flowers was greatly broadened. In
that the liquid droplets from the ovules and the pollen flowers pollinated by the long-tongued insects, the
in the male cones were nutritious foods. Some of petals became fused into a tubular corolla with the
these beetles, returning regularly to the newly found supply of nectar concealed at its base. The carpels
source of food, would have accidentally carried were similarly fused into a compound ovary with a
pollen to the ovules. For some Mesozoic plants, this
new method of pollination may have represented a
r
more efficient method of cross-pollination than did beetles and small flies and to restrict visitors to those
the releasing of enormous quantities of pollen into the
air. Through natural selection, they would develop
D is
adaptations to the potentialities of beetle pollination.
t insects – the bees, moths, and long-tongued flies –
that fly regularly from flower to flower of the same
species. This was a great step forward in floral
N ot
The ovules, first of all, must be placed behind some
protective wall to prevent their being chewed up by
design: It marked a transition from promiscuous
pollination by miscellaneous unspecialized insects to
restricted pollination by specialized and flower-
Do
the beetles. One means of accomplishing this constant animals.
isolation would be to fold the ovule-bearing leaf or
branch into a hollow, closed carpel. The pollen- Material used in this test passage has been adapted from the
collecting function would then have to be transferred following source:
V. Grant, The Pollination of Flowers. ©1965 by Harper and
from the individual ovules to a central stigma serving Row.
all the ovules in the carpel.
78. The ideas in the passage seem to derive primarily
The beetles could be drawn to the stigma by a special
from:
secretion of nectar, which would replace the droplets
previously given off by the individual ovules. A A) evidence on the behavior of living insect species.
beetle visiting the stigma would be apt to leave B) speculation based on an accepted theory.
behind sufficient pollen for the fertilization of
numerous ovules. The number of seeds formed in a C) knowledge of ongoing evolutionary trends.
single pollination would no longer be one, as in the D) facts observable in the fossil record.
wind-pollinated ancestor, but ten or twenty. So the
transition from wind to beetle pollination would
increase the fertility of the plant.
Sharing or reproducing this material in any form is a violation of the AAMC copyright Page 33 of 62
79. The passage discussion most clearly suggests the 81. Which of the following findings would most
hypothesis that as flowers evolve they compromise the author’s conclusions about the
increasingly form reproductive structures that: evolution of flowers with corollas?
A) are attractive to numerous insects. A) Flowers with corollas often become extinct shortly
after their insect pollinator becomes extinct.
B) accommodate the structure of insects.
B) The long-tongued insects of the Tertiary Period
C) exclude insects not of a particular type.
had not developed wings.
D) determine the direction of insect evolution.
C) The genes that control the formation of a corolla
also cause vulnerability to a fungus.
80. The author’s reasoning about flower evolution
could most reasonably be extended to questions D) Flowers without corollas can be chemically
about: stimulated to form this structure.
r
B) The reason that bees, moths, and butterflies
t
tubular corollas existed
Do
Sharing or reproducing this material in any form is a violation of the AAMC copyright Page 34 of 62
r
impose an unprecedented degree of artificiality on the for” not only between generations but also within
world but to participate in a collective, cumulative
learning experience. A vital part of this facility is
language, a vehicle for complex thought processes.
ot
only from its own experience and that of its parents
N
but also from the collective wisdom of all previous
the way an individual behaves or grows; if favored by
selection, genetic mutations may become dominant in
a population after tens of thousands of years. Cultural
Do
generations. evolution deals with novel artifacts, which sometimes
transform entire societies virtually instantaneously –
Combine consciousness and culture in a species and a witness the effects of the electronic computer today.
truly different kind of animal is created. This animal
can build a civilization. And within civilization exists Material used in this test passage has been adapted from the
an animal with concerns that can be totally divorced following source:
S.J. Gould, Ever Since Darwin: Reflections in Natural
from the business of subsistence, an animal with History. ©1977 by S.J. Gould.
frontiers that can extend beyond its immediate
material surroundings, an animal that wants – indeed
83. The author implies that an animal without
needs – to discover things about itself and the world it
consciousness is not:
inhabits. This animal has an insatiable appetite for
knowledge. A) aware of its individuality.
B) able to learn from its experiences.
One characteristic of our scientific civilization is
rapid change, whether it be in fashion, technology, or C) able to express its knowledge.
political alliances. Change is the core of the D) fully aware of its surroundings.
Darwinian world of natural selection, too: adaptation
to shifting circumstances and environments. The
Sharing or reproducing this material in any form is a violation of the AAMC copyright Page 35 of 62
84. The author’s argument that culture contributes to 86. Assume that few humans give much thought to
human evolution depends on the acceptance of anything except their immediate material
which of the following premises? surroundings. Which of the following hypotheses
does this assumption suggest?
A) Darwin’s theory revolutionized the conception of
human nature. A) Consciousness provides no significant advantages.
B) Consciousness and culture give humans a sense of B) Cultural evolution has not kept pace with genetic
specialness. evolution.
C) Only humans are curious about the world around C) Language does not make complex thought
them. possible.
D) Genetic mutations do not cause rapid social D) Civilization does not create a desire to understand.
changes.
87. The author’s discussion of the relationship of
85. Which of the following situations would NOT be language to culture and complex thought implies
an example of the operation of natural selection that:
within cultural evolution? A) before a culture existed, language could not have
A) Foreign languages are taught to young children in developed.
private schools but not to those in public schools. B) nonhuman animals may have languages but not
e
B) The most popular television shows are those that cultures.
glorify violence, and the number of such shows
increases.
t
C) In a period of economic decline, only the D) teaching is a particularly important function of
candidates with coherent social programs are
elected.
D) As each generation creates terminology, the
t D is language.
N
language is gradually transformed.
o
Do
Sharing or reproducing this material in any form is a violation of the AAMC copyright Page 36 of 62
r
world as a battleground for their two forces. At the Material used in this test passage has been adapted from the
end of history, Ahura Mazda will win the great
i
struggle to destroy evil and so achieve a universe that
will be wholly good forever.
D s t following source:
M. Boyce, Zoroastrians: Their Religious Beliefs and
Practices. ©1979 by M Boyce.
N ot
Zoroaster left little scope for heresy or schism. Yet
88. The author asserts that in Zoroastrianism, both
humans and the two primal spirits are:
Do
they must have given the magi (Zoroastrian converts A) required to choose between good and evil.
of the sixth century B.C.) much new matter to ponder. B) destined to exist eternally.
One of the most striking elements in the prophet’s
teachings was the concept of history having an end. C) creations of Ahura Mazda.
The magi had also become familiar with very D) subordinate to Zurvan.
different Babylonian speculations about history being
divided into great recurrent cycles of time in which all
events repeated themselves; and contrasting such 89. Suppose it is discovered that the first Zurvanites
were influenced more by Indian than by
theories with Zoroaster’s teachings may well have led
Babylonian conceptions of cyclical time. Does
them to reflect much on time and its nature.
this discovery support the author’s argument?
The result was the Zurvanite heresy. The word zurvan A) Yes; it confirms it.
means time. The Zurvanites came to believe that time, B) No; it does not affect it.
Zurvan, did not merely provide the framework for
events but was actually in control of them, hence a C) No; it weakens it.
sentient being. They found their main scriptural D) No; it disproves it.
justification for this belief in Zoroaster’s verse:
“Truly there are two primal spirits, twins, renowned
Sharing or reproducing this material in any form is a violation of the AAMC copyright Page 37 of 62
90. Which of the following discoveries, if genuine, 92. The Orphic Greeks of the sixth century B.C. held
would most weaken the author’s argument? that history began when Chronos (time) gave
birth to the twin forces of divine Aether and dark
A) A text by a pre-Zoroastrian asserting that history
Chaos. The similarity between this theory and
would eventually end
Zurvanism could NOT have resulted from the
B) A text by an early Zurvanite denying that history influence of:
would ever end
A) the Orphic Greeks on the Zurvanites.
C) A text by Zoroaster asserting that Ahura Mazda
B) the Zurvanites on the Orphic Greeks.
and Angra Mainyu had a common parent
C) the Orphic Greeks on Zoroaster.
D) A text by Zoroaster foretelling the development of
the Zurvanite heresy D) Zoroaster on the Orphic Greeks.
i b ut e
r
D) Some interpretations of religious doctrines are
inconsistent.
D is t
N ot
Do
Sharing or reproducing this material in any form is a violation of the AAMC copyright Page 38 of 62
Writing Sample
Time: 60 minutes
2 Prompts, separately timed:
30 minutes each
This is a test of your writing skills. The test consists of two parts. You will have 30 minutes to complete each
part. Use your time efficiently. Before you begin writing each of your responses, read the assignment carefully
to understand exactly what you are being asked to do. Because this is a test of your writing skills, your
response to each part should be an essay of complete sentences and paragraphs, as well organized and clearly
written as you can make it in the time allotted.
i b ut e
D is t r
N ot
Do
This document has been encoded to link this download to your member account. The
AAMC and its Section for the MCAT hold the copyrights to the content of this Practice
Test. Therefore, there can be no sharing or reproduction of materials from the Practice
Test in any form (electronic, voice, or other means). If there are any questions about the
use of the material in the Practice Test, please contact the MCAT Information Line (202-
828-0690).
39 of 62
Governments have a responsibility to regulate companies that provide necessary services to citizens.
Write a unified essay in which you perform the following tasks. Explain what you think the above
statement means. Describe a specific situation in which a government might not have a responsibility to
regulate a company that provides a necessary service to citizens. Discuss what you think determines
whether or not governments have a responsibility to regulate companies that provide necessary services to
citizens.
i b ut e
D is t r
N ot
Do
Sharing or reproducing this material in any form is a violation of the AAMC copyright Page 40 of 62
Only those politicians who have learned the art of compromise can achieve their political goals.
Write a unified essay in which you perform the following tasks. Explain what you think the above
statement means. Describe a specific situation in which a politician might achieve a political goal without
compromising. Discuss what you think determines when politicians should compromise to achieve a
political goal.
i b ut e
D is t r
N ot
Do
Sharing or reproducing this material in any form is a violation of the AAMC copyright Page 41 of 62
Biological Sciences
Time: 70 minutes
Questions: 95 - 146
Most questions in the Biological Sciences test are organized into groups, each containing a descriptive passage.
After studying the passage, select the one best answer to each question in the group. Some questions are not
based on a descriptive passage and are also independent of each other. If you are not certain of an answer,
eliminate the alternatives that you know to be incorrect and then select an answer from the remaining
alternatives. Indicate your selected answer by marking the corresponding answer on your answer sheet. A
periodic table is provided for your use. You may consult it whenever you wish.
i b ut e
D is t r
N ot
Do
This document has been encoded to link this download to your member account. The AAMC
and its Section for the MCAT hold the copyrights to the content of this Practice Test. Therefore,
there can be no sharing or reproduction of materials from the Practice Test in any form
(electronic, voice, or other means). If there are any questions about the use of the material in the
Practice Test, please contact the MCAT Information Line (202-828-0690).
1 2
Periodic Table of the Elements
H He
1.0 4.0
3 4 5 6 7 8 9 10
Li Be B C N O F Ne
6.9 9.0 10.8 12.0 14.0 16.0 19.0 20.2
11 12 13 14 15 16 17 18
Na Mg Al Si P S Cl Ar
23.0 24.3 27.0 28.1 31.0 32.1 35.5 39.9
19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36
K Ca Sc Ti V Cr Mn Fe Co Ni Cu Zn Ga Ge As Se Br Kr
39.1 40.1 45.0 47.9 50.9 52.0 54.9 55.8 58.9 58.7 63.5 65.4 69.7 72.6 74.9 79.0 79.9 83.8
37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54
Rb Sr Y Zr Nb Mo Tc Ru Rh Pd Ag Cd In Sn Sb Te I Xe
85.5 87.6 88.9 91.2 92.9 95.9 (98) 101.1 102.9 106.4 107.9 112.4 114.8 118.7 121.8 127.6 126.9 131.3
55 56 57 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86
Cs Ba La* Hf Ta W Re Os Ir Pt Au Hg Tl Pb Bi Po At Rn
132.9 137.3 138.9 178.5 180.9 183.9 186.2 190.2 192.2 195.1 197.0 200.6 204.4 207.2 209.0 (209) (210) (222)
87 88 89 104 105 106 107 108 109 110 111 112 114 116
Fr Ra Ac† Rf Db Sg Bh Hs Mt Ds Uuu Uub Uuq Uuh
(223) (226) (227) (261) (262) (266) (264) (277) (268) (281) (272) (285) (289) (289)
58 59 60 61 62 63 64 65 66 67 68 69 70 71
t e
* Ce Pr Nd Pm Sm Eu Gd Tb Dy Ho Er Tm Yb Lu
u
140.1 140.9 144.2 (145) 150.4 152.0 157.3 158.9 162.5 164.9 167.3 168.9 173.0 175.0
90 91 92 93 94 95 96 97 98 99 100 101 102 103
† Th
232.0
Pa
(231)
U
238.0
is
Np
t ri
(237)
b Pu
(244)
Am
(243)
Cm
(247)
Bk
(247)
Cf
(251)
Es
(252)
Fm
(257)
Md
(258)
No
(259)
Lr
(260)
N ot D
Do
Passage I
The two divisions of the autonomic nervous system (ANS) are the parasympathetic (PS) and the sympathetic
(S) divisions. Structurally, the S ganglia appear near the spinal cord in the thoracic and lumbar regions and
connect with each other to form the sympathetic trunk. PS innervation originates in either the brain stem or the
sacral region of the spinal cord. The PS ganglia lie in or near the organs they connect to but do not connect with
each other (Figure 1). The neurotransmitter acetylcholine is released at the ganglia in both the PS and the S
divisions. However, acetylcholine is released at the motor synapse (at the organ) only in the PS division; the
corresponding neurotransmitter in the S division is norepinephrine.
i b ut e
D is t r
N ot
Do Figure 1 General structure of autonomic nervous system, showing innvervation of iris muscles. (Figure is not
proportional.)
A typical example of the function of the ANS is the regulation of pupil size by the iris musculature. The
circular muscle of the iris is innervated by the PS division of the ANS, and the radial muscles are innervated by
the S division (Figure 1).
The motor portion of the pupillary light reflex (constriction of the pupil in bright light to protect the retina from
excessive illumination) consists of the PS innervation of the circular muscle. Light entering the retina stimulates
the optic nerve to send impulses to the midbrain, which in turn activates the PS pathway leading to the circular
muscle. This results in constriction of the pupils. In contrast, when the PS pathway is not being stimulated (as in
darkness), signals from the S system to the radial muscles predominate, causing the pupils to dilate.
Sharing or reproducing this material in any form is a violation of the AAMC copyright Page 44 of 62
95. Opiates, such as morphine and heroin, increase 98. The autonomic nerve fibers that directly
impulse traffic on the PS nerves to the iris. innervate the heart to cause cardiac slowing are:
Therefore, after a morphine injection, the pupils A) sympathetic motor fibers.
will be more:
B) sympathetic sensory fibers.
A) constricted, due to release of acetylcholine.
C) parasympathetic motor fibers.
B) constricted, due to release of norepinephrine.
D) parasympathetic sensory fibers.
C) dilated, due to release of acetylcholine.
D) dilated, due to release of norepinephrine. 99. Based on information in the passage, would the S
or the PS division of the ANS be expected to
96. Drugs affecting the ANS may have either an produce a more rapid systemic (whole-body)
“active” mechanism (that mimics the activity of response to a stimulus?
the PS or the S division) or a “passive”
A) The S division, because its ganglia are
mechanism (that blocks the effect of the opposing interconnected
division). The drug atropine prevents
acetylcholine from attaching to its receptors on B) The S division, because it secretes norepinephrine
the circular muscle. Is this mechanism active or C) The PS division, because its ganglia are not
passive? interconnected
A) Passive, because PS innervation is blocked D) The PS division, because it secretes acetylcholine
B) Passive, because S innervation is blocked
C) Active, because PS innervation is mimicked
t
97. If acetylcholine is removed from the circulation the pupil to:
o
faster than norepinephrine is, which of the A) dilate, due to decreased acetylcholine levels.
N
following autonomic processes would be most
rapidly inactivated? B) dilate, due to increased acetylcholine levels.
Do
A) Dilation of the pupils C) constrict, due to decreased acetylcholine levels.
B) Dilation of blood vessels in the skeletal muscles D) constrict, due to increased acetylcholine levels.
C) Rise in blood pressure
D) Stimulation of digestive secretions
Sharing or reproducing this material in any form is a violation of the AAMC copyright Page 45 of 62
Passage II
i b ut e
r
frog.
D is t
N ot
Do Figure 1 Responses to freezing and thawing in Rana
sylvatica
Sharing or reproducing this material in any form is a violation of the AAMC copyright Page 46 of 62
r
throughout the body.
N
Figure 2 Effects of exogenous glucose on frog
response to freezing
Do
101. Presumably, hyperglycemia promotes cellular
104. According to the passage, which of the
dehydration because:
following parts in the frozen body of a freeze-
A) glucose, as an energy source, accelerates the tolerant frog would contain ice?
osmotic work performed by plasma membranes. I. Cytoplasm
B) glucose, as an energy source, accelerates plasma II. Blood plasma
membrane ion exchange pumps. III. Lymph
Sharing or reproducing this material in any form is a violation of the AAMC copyright Page 47 of 62
105. During what time period of the freeze-thaw 107. According to the passage, which of the
episode shown in Figure 1 were the frog’s following physiological conditions would
tissues relying entirely on anaerobic respiration? increase a wood frog’s chance of surviving
freezing temperatures most effectively?
A) Before 0 hours
A) Dehydration
B) Between 0 and 6 hours
B) Ample liver glycogen stores
C) Between 0 and 24 hours
C) High blood hemoglobin concentration
D) Between 12 and 26 hours
D) High tissue glucose concentration
106. Do the results presented in Figure 2 support the
hypothesis that glucose has a cryoprotective role
in frogs?
A) Yes; survival and protection against hemolysis are
promoted by exogenous glucose.
B) Yes; death caused by freezing is directly
proportional with the extent of hemolysis.
C) No; injected glucose lowered blood hemoglobin
levels, suggesting that the survival rates are not
related to the treatment.
D) No; injected saline promoted hemolysis,
i b ut e
r
suggesting death was most likely related to
circulatory collapse.
D is t
N ot
Do
Sharing or reproducing this material in any form is a violation of the AAMC copyright Page 48 of 62
Passage III
i b ut e
r
Table 1. The identity of Compound C was confirmed
by comparing its IR spectrum with a reference
spectrum.
D is t
N
Table 1 Possible Structures of Compound C
ot
Do 108. The solubility data indicate that Compound C
most likely contains which of the following
functional groups?
A) Carboxylic acid and amide
B) Amine and amide
C) Amide and nitro
D) Amine and carboxylic acid
Sharing or reproducing this material in any form is a violation of the AAMC copyright Page 49 of 62
109. The IR spectrum of each compound in Table 1 111. Based on the passage, Compound A most likely
should contain a strong, sharp band at contains which of the following functional
approximately: groups?
A) 3150 cm-1. A) Ether
B) 2100 cm-1. B) Ester
C) 1700 cm-1. C) Ketone
-1
D) 1000 cm . D) Aldehyde
110. A sample of 4-aminobenzoic acid is 112. The compounds in Table 1 can be most
contaminated with a small percentage of unequivocally distinguished from each other by
camphoric acid. What can be determined about comparing their:
the melting point of this mixture?
A) solubility behaviors.
A) The mixture will have a broad melting range
B) reactivities toward alcohols.
above 189oC.
C) melting points.
B) The mixture will have a broad melting range
below 188oC. D) molecular weights.
C) The mixture will have a sharp melting point of
186oC.
D) The mixture will have a sharp melting point of
189oC.
i b ut e
D is t r
N ot
Do
Sharing or reproducing this material in any form is a violation of the AAMC copyright Page 50 of 62
r
pilus, bestowing new genes upon the recipient cell. reaction to the antibiotics.
Conjugation may occur between members of the
same, or different, bacterial species.
t
hospitalization.
A man was hospitalized with a ruptured appendix and
N o
received massive doses of the antibiotics ampicillin
and kanamycin over a period of weeks. Shortly after
D) chance mutations in a few E. coli before the
treatment made these cells and their descendants
Do
leaving the hospital, he contracted Mycobacterium antibiotic-resistant.
tuberculosis, the pathogen that causes tuberculosis,
from a coworker. He was again hospitalized and 115. Tests performed on the M. tuberculosis strain
treated with large doses of first ampicillin and then infecting the patient’s coworker indicated that
kanamycin, with no effect. Recovery was rapid when the strain was susceptible to both ampicillin and
a third antibiotic, streptomycin, was administered. kanamycin, and the coworker was successfully
treated. The M. tuberculosis most likely
survived in the patient because it had:
A) undergone conjugation with cells of resistant
E. coli.
B) undergone an antibiotic-induced mutation that
conferred antibiotic resistance.
C) reproduced more rapidly than the strain in the
coworker.
D) adapted to its new environment by modifying its
metabolism.
Sharing or reproducing this material in any form is a violation of the AAMC copyright Page 51 of 62
116. The patient’s ruptured appendix required 118. If the E. coli population in the colon is severely
treatment with antibiotics because he had a reduced due to extended antibiotic treatment,
bacterial infection caused by: which of the following effects on digestion and
A) M. tuberculosis. nutrition are most likely to occur?
B) E. coli entering the colon from the appendix. A) Deficiencies of necessary digestive enzymes
C) E. coli entering the abdominal cavity from the B) Deficiencies of specific vitamins
appendix. C) Intestinal tract infections due to increased
D) E. coli entering the appendix from the colon. populations of other bacteria
D) Greatly reduced absorption of caloric nutrients
117. Following the antibiotic treatment, the patient’s
colon will be recolonized by other bacteria. The 119. Bacterial conjugation is similar to the sexual
factor that will ultimately determine whether reproduction of eukaryotic organisms in that it:
antibiotic-resistant E. coli cells will persist in
A) results in genetic recombination.
the colon at this time is E. coli’s ability to:
B) results in the combination of 2 sets of
A) produce more viable descendants than the other
chromosomes within a single nucleus.
bacteria.
C) increases the number of organisms in the
B) produce more vitamin B12 than the other bacteria.
population.
C) metabolize glucose faster than the other bacteria.
D) cause fewer incidences of diarrhea or constipation
r
than the other bacteria.
D is t
N ot
Do
Sharing or reproducing this material in any form is a violation of the AAMC copyright Page 52 of 62
120.
i b ut e D) At I and IV
r
122. Suppose that in a randomly mating population
Do
A) 160
B) 400
C) 480
D) 600
Sharing or reproducing this material in any form is a violation of the AAMC copyright Page 53 of 62
Passage V
i b ut e
r
the relaxation of the intact and scraped rings in
response to different concentrations of acetylcholine
was compared.
D is t
N ot Figure 1 Effect of acetylcholine on tension in rabbit
aorta with and without endothelium
NE = norepinephrine added; ACH = acetylcholine;
Do
at washout, NE and ACH are removed
Sharing or reproducing this material in any form is a violation of the AAMC copyright Page 54 of 62
123. In Figure 1, which of the following observations 126. The two primary factors that normally
led to the conclusion that intact endothelium is determine the level of blood pressure are:
necessary for the relaxation of smooth muscle A) the blood concentration of L-NMMA and
when acetylcholine (ACH) is applied? norepinephrine.
A) The tension initially changes when norepinephrine B) the cardiac output and the resistance to blood flow.
(NE) is added.
C) the blood volume and the amount of L-arginine in
B) The tension decrease occurs more quickly in the the diet.
ring without endothelium.
D) the heart rate (heartbeats/minute) and the cardiac
C) The tension decreases upon addition of stroke volume.
10-7MACH, only in the ring with endothelium.
D) The tension decreases during washout in the ring 127. Increased vasoconstriction has an important role
without endothelium. in which of the following situations?
A) Causing the decrease in blood pressure associated
124. From the data in Figure 1, one can conclude that with fainting
the sensitivity of aortic smooth muscle to
acetylcholine is: B) Increasing blood flow to muscle during exercise
A) decreased by the presence of norepinephrine. C) Increasing blood flow to skin during blushing
D) Maintaining blood pressure during a hemorrhage
e
B) increased by the presence of norepinephrine.
C) increased at least 10 times by the presence of the
endothelium.
t
125. The concentration range within which muscle A) increase its sensitivity to acetylcholine.
o
tension is most sensitive to acetylcholine
N
(Figure 1) is: B) cause the ring to dilate (reduce its tension).
Do
A) less than 10-8M. C) cause the ring to contract (increase its tension).
B) near 10-7M. D) prevent norepinephrine from increasing ring
tension.
C) greater than 10-6M.
D) much wider in the ring without endothelium than
in the ring with endothelium.
Sharing or reproducing this material in any form is a violation of the AAMC copyright Page 55 of 62
These questions are not based on a descriptive 131. Most fungal spores are:
passage and are independent of each other.
A) metabolically active and diploid.
129. Which of the bromomethanes is LEAST polar? B) metabolically inactive and haploid.
A) CBr4 C) relatively sensitive to environmental changes.
B) CHBr3 D) encased in a porous nuclear membrane.
C) CH2Br2
132. Hemophilia, a disease in which the time
D) CH3Br required for blood to clot is greatly prolonged, is
determined by a sex-linked gene. Suppose a
130. The phenomenon exemplified in the equilibrium man with normal blood clotting marries a
equation below is called: woman with normal blood clotting whose father
was a hemophiliac. If this couple has three sons,
what is the probability that hemophilia will be
transmitted to all three of them?
A) 1/8
A) reduction.
B) 1/4
B) resonance.
C) 3/8
e
C) tautomerism.
D) mutarotation.
ri b ut D) 1/2
D is t
N ot
Do
Sharing or reproducing this material in any form is a violation of the AAMC copyright Page 56 of 62
Passage VI
Lipopolysaccharide antigens on the surface of gram-negative bacteria are called endotoxins. People infected
with gram-negative bacteria sometimes develop septic shock syndrome in response to the endotoxins (see
Figure 1).
i b ut e
D is t r
N ot
Do Figure 1 Cascade of events that is important in causing septic shock
To reduce the mortality rate of septic shock two treatment plans were proposed.
Treatment 1: Administration of a general anti-inflammatory drug to block the inflammatory cell response in
patients infected with endotoxin
Treatment 2: Administration of an antibody that blocks the attachment site for the endotoxin-binding protein
complex on macrophages
Patients were selected who had signs of septic shock. They were treated with either Treatment 1 drug,
Treatment 2 drug, or placebo.
Sharing or reproducing this material in any form is a violation of the AAMC copyright Page 57 of 62
133. For Treatment 2 to be effective, the antibody 135. Fever in septic shock leads to which of the
must: following compensation mechanisms?
A) stimulate macrophage activation. A) Dilation of capillary beds in the skin
B) stimulate T-cell production. B) Increased skeletal muscle activity
C) inhibit T-cell production. C) Decreased respiration rate
D) inhibit macrophage activation. D) Decreased fluid loss
134. What is a danger of using the drug in 136. If the anti-inflammatory drug in Treatment 1
Treatment 1? interfered with DNA replication, in which phase
of the cell cycle would cells tend to be arrested?
A) It may decrease endogenous antibacterial
activities. A) G0 phase
B) It may increase the platelet count. B) G1 phase
C) It may decrease the red blood cell count. C) S phase
D) It may increase the blood pressure. D) G2 phase
i b ut e
D is t r
N ot
Do
Sharing or reproducing this material in any form is a violation of the AAMC copyright Page 58 of 62
Acetoacetic ester (1) and malonic ester (2) serve as Product number Name
synthetic precursors for the preparation of a variety of 3 2-butanone
methyl ketones and carboxylic acids. The starting 4 2-pentanone
ester is alkylated, saponified, acidified, and pyrolyzed 5 4-methyl-2-pentanone
(heated strongly); a typical procedure is shown in 6 4-methyl-2-hexanone
Scheme 1. The final product is determined by the
7 pentanoic acid
alkylating agent.
8 3-methylbutanoic acid
9 4-methylpentanoic acid
10 decanoic acid
i b ut e D) Isopropyl iodide
r
138. The saponification product is acidified to
Scheme 1
D is t convert:
A) an ester into an acid.
N
sodium ethoxide/ethanol to one of two possible
ot B) an acid into a salt.
C) a salt into an acid.
Do
enolate ions, which is stabilized by delocalization of D) an ester into a salt.
charge to two oxygen atoms. The enolate ion is then
alkylated by an alkyl halide. A second alkylation step 139. How can 3-ethyl-2-pentanone, below, be
may be incorporated into the synthesis, but a different synthesized starting with acetoacetic ester 1?
base is sometimes used for the second enolization and
alkylation.
Sharing or reproducing this material in any form is a violation of the AAMC copyright Page 59 of 62
i b ut e
D is t r
N ot
Do
Sharing or reproducing this material in any form is a violation of the AAMC copyright Page 60 of 62
These questions are not based on a descriptive 144. HIV (human immunodeficiency virus) is a
passage and are independent of each other. retrovirus, an RNA virus that can insert itself
into the human genome. This virus can
141. Inflation of the lungs in mammals is reproduce in host cells because it contains:
accomplished by: A) enzymes that destroy T cells.
A) diffusion of gases. B) viral DNA that is compatible with human DNA.
B) active transport of gases. C) core proteins rather than DNA.
C) positive pressure pumping action. D) reverse transcriptase.
D) negative pressure pumping action.
145. The sequence of events in the human menstrual
142. An organism is likely to be a bacterium rather cycle involves close interaction among which
than a virus if it: organs?
A) reproduces via fission. A) Hypothalamus-thyroid-ovary
B) has a rigid outer covering. B) Hypothalamus-pituitary-ovary
C) lacks a nuclear membrane. C) Pituitary-thyroid-ovary
D) contains both RNA and protein. D) Pituitary-adrenal glands-ovary
t
linked to the gene for flower color.
o
B) No; aldosterone causes Na+ secretion by kidney Homozygous long, white plants are crossed with
N
tubules. homozygous short, red plants (P1 generation).
The resulting offspring (F1) are bred randomly
Do
C) Yes; aldosterone causes Na+ reabsorption by
kidney tubules. among themselves. How many different color
and leaf-length phenotypes will occur in the F2
D) Yes; aldosterone causes Na+ secretion by kidney generation?
tubules.
A) 2
B) 3
C) 4
D) 6
Sharing or reproducing this material in any form is a violation of the AAMC copyright Page 61 of 62
i b ut e
D is t r
N ot
Do
Page 62 of 62