HOSPITAL PHARMACY (ASSIGNMENT)

DRUG: RIBAVIRIN

i. CLASS OF DRUG: Ribavirin is used with an interferon medication such as peginterferon alfa-2a or
peginterferon alpha-2b [PEG-Intron]) to treat hepatitis C in people who have not been treated
with an interferon before. Ribavirin is in a class of antiviral medications called nucleoside
analogues.

ii. INDICATION: Ribavirin, also known as tribavirin, is an antiviral medication used to treat RSV
infection, hepatitis C, and viral hemorrhagic fever.For hepatitis C it is used with other
medications such as simeprevir, sofosbuvir, peginterferon alfa-2b or peginterferon alfa-2a.

iii. SIDE EFFECTS: Headache, muscle pain, dry mouth, nausea; vomiting, stomach pain, loss of
appetite, weight loss.

iv. ADVERSE EFFECTS: Anorexia, Myalgia, Neutropenia, Dyspnea, Arthralgia.

v. DOSE STRENGTH AND DOSAGE FORMS AVAILABLE:

Tablet: 200mg, 400mg, 600mg.

Inhalation: 6g/vial
Oral solution : 40mg/Ml

vi. CONTRAINDICATION: hypersens. to drug/class/compon., pregnancy, male partners of pregnant

women, significant or unstable cardiac disease, hemoglobinopathies, hemoglobinopathies.

vii. DRUG INTERACTIONS: Tell your doctor about all your current medicines and any you start or
stop using, especially:
azathioprine; or medicines to treat HIV or AIDS.

viii. PREGNANCY RISK FACTORS: Ribavirin can cause birth defects or death in an unborn baby. Do not
use this medicine if you are pregnant, or if you are a man and your sexual partner is pregnant.
Use 2 forms of birth control to prevent pregnancy while either sexual partner is taking ribavirin,
and for at least 6 months after treatment ends.
ix. MOST RUNNING AND FAMOUS BRAND: Rebetol (ribavirin) is an antiviral medication.
Rebetol must be used together with an interferon alfa product (such as Pegasys, PegIntron, Sylatron, or Intron A)
to treat chronic hepatitis C.

SUBMITTED BY: WAJEEHA JABEEN BAIG

ROLL NO: 78
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