General

BLOCK

LABORATORY
Biology2 NAMES
1. ______________________________
2. ______________________________
GROUP #

DATE
SCHEDULE Science, Technology, Engineering
3. ______________________________ and
4. ______________________________
Mathematics
5. ______________________________
6. ______________________________

Laboratory Activity 7
PEDIGREE ANALYSIS

INTRODUCTION

Pedigree analysis is the process of examining a pedigree to determine the pattern of

inheritance for a trait. Pedigrees are often used to determine if a trait is dominant or recessive. A
pedigree chart displays a family tree, and shows the members of the family who are affected by a
genetic trait. Genetic counsellor uses pedigree charts to help determine the distribution of a disease
in an affected family.

Significant symbols:

OBJECTIVES

a. Make a Pedigree Analysis in your family using a simple genetic trait or disease.
b. Construct pedigrees and predict genotypes based on pedigree analysis

MATERIALS

 Long bond papers

 Markers/ pens

Pedigree Analysis
PROCEDURES
1. Start by listing the traits common in your family. Have a separate list of your mother side
and father side.
2. Identify at least three to four generations and make use of the necessary symbols in
identifying the traits common in your family.

QUESTIONS

1. The trait represented by the colored circles and squares below is inherited as a dominant allele.
This is not a sex- linked trait. Shaded individuals show the dominant trait.

2. What is the probable genotype of each individual?

3. Are there any homozygous dominant individuals in the pedigree above? How do you know?

4. What is the probability of the trait appearing in offspring if 7 should marry 9?

5. What is the probability of the trait appearing in offspring if 8 should marry 10?

Pedigree Analysis
 Below is part of the pedigree of Queen Victoria of England. This pedigree represents
the occurrence of hemophilia in her family. Only part of her family members has been included.
Refer to this pedigree to answer the following questions:
Queen Victoria

1. How many male grandchildren were hemophiliacs?

_____________________________________________________________________________

2. How many of the great-grandchildren were hemophiliacs?

________________________________________________________
How many were girls? __________________________________
How many were boys? _________________________________

3. Is it more likely for males or females to get hemophilia?

______________________________________________________________________________

Explain your answer. __________________________________________________________

4. Why were all the carriers in Queen Victoria’s family female?

______________________________________________________________________________

Pedigree Analysis