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Endovenous Radiofrequency Ablation of The Saphenous Vein The VNUS Closure Procedure
Endovenous Radiofrequency Ablation of The Saphenous Vein The VNUS Closure Procedure
VN20-86-E 4/09
25 Million people suffer from venous reflux disease,
the underlying cause for most varicose veins
Cardiac Arrhythmias
0 5 10 15 20 25
Millions
Prevalence and Etiology of
Venous Insufficiency
Image source: Fundamentals of Phlebology: Venous Disease for Clinicians. Illustration by Linda S. Nye. American College of Phlebology 2004.
Pathophysiology of Venous Insufficiency
Risk Factors and Symptoms of
Venous Insufficiency
Risk factors of venous insufficiency: Symptoms of venous insufficiency:
• Using a catheter-based
approach, the VNUS
ClosureFAST™ catheter
delivers radiofrequency (RF)
energy to the vein wall
VNUS Closure®
Visual Results
100%
90%
80%
70%
60%
p < 0.0001 51.3%
50%
40%
30%
20%
10%
2.2%
0%
ClosureFAST Laser
RECOVERY Trial7: Ecchymosis
A Prospective, Multi-Center, Randomized Study
100%
80.5% 74.3%
80% 66.7%
60%
33.0% 35.0%
40%
18.6% 22.5%
20%
2.2%
0%
2 Days 7 Days 14 Days 30 Days
ClosureFAST Laser
RECOVERY Trial7: Conclusion
A Prospective, Multi-Center, Randomized Study
Indication:
• The ClosureFAST Catheter is intended for endovascular
coagulation of blood vessels in patients with superficial
venous reflux
Contraindications:
• Patients with thrombus in the vein segment to be treated
Sources of Reflux in
Venous Ulcer Patients8
Superficial Perforating Deep
79% 63% 50%
• Minimally invasive
• Outpatient procedure