serine Print (= THEPHARMACY EXAMINING BOARD OF CANADA '& Providing Excellence in Certification for the Pharmacy Profession Sample Questions Pharmacist Evaluating Examination Sample Questions The following sample questions are NOT intended or designed to be a sample examination, and do NOT represent an exact model of the Pharmacist Evaluating Examination in terms of difficulty and proportion of topics. However, individually, these questions are intended to be representative, in format and phrasing style, of the types of questions found on the Pharmacist Evaluating Examination. They also illustrate a variety of the subject areas contained in the examination blueprint. Please note that these questions are reviewed and updated periodically. Please see below for the answers to these sample questions. BIOMEDICAL SCIENCES Folic acid has tetrahydrofolate coenzyme activity which is based on the: a. pyrimidine ring b. purine ring ©. pyrazine ring d. pteridine ring e. pyridine ring 2 Enkephalins are peptides that: a, have narcotic antagonist activity, b. exert actions resembling those of opiates. c. are found only in the central nervous system. d. cause blood vessel wall relaxation, e. transmit pain impulses. 3 B-Carotene is the precursor of: a. retinol b. thiamine. c. calciferol. d. riboflavin. e. retinoic acid. 4 True statements regarding transcription include which of the following? a. The enzyme responsible for initiating transcription is RNA polymerase. b. The enzyme responsible for initiating transcription is DNA polymerase. . During transcription, the genetic information contained in the nucleotide sequence of tRNA is translated into a protein structure. d. The process of transcription includes the splicing of exons. e. Following initiation, the next stage of transcription is termination 5 Diphtheria is caused by: a. Plasmodium, b. Vibrio. c. Shigella. nw pebe.calindex phpii_a/3074a,_eprnttruetart_i’3126.him ansame Print d. Neisseria, e. Corynebacterium. 6 Identify the correct pathway of blood flow from the small intestine to the liver: a. haemorrhoidal vein — portal vein. b. mesenteric vein — portal vein , haemorrhoidal vein — inferior vena cava. d. mesenteric vein — hepatic artery. e. gastric vein — hepatic vein, 7 Lactose intolerance is classified as a(n): a. allergy. b. enzyme deficiency. c. mineral deficiency. d. transporter abnormality. e. vitamin deficiency. 8 Parkinson's disease is characterized by a deficiency of: a. acetylcholine in the motor cortex, b. noradrenaline in the spinal motor neurons. c. gamma amino butyric acid (GABA) in inhibitory pathways. d. dopamine in the nigrostriatal pathway. e. serotonin in the brain stem 9 The blood volume of the average adult is approximately: a SL. b.10L, 6.15, d.20L, e251, 10 Common etiologic agents of community-acquired pneumonia include: Escherichia coli I Haemophilus influenzae. Ill Mycoplasma pneumoniae. a tony b.llonly c. Land lonly 4. land Ill only e.| lland ill 11 Gamma aminobutyric acid (GABA) is: the major inhibitory neurotransmitter in the brain. Il found primarily in interneurons. I synthesized from glycine. a lonly b.tllonly ¢. land Il only land Ill only e | land tt 12 All of the following statements are true regarding chronic inflammation, EXCEPT: a. it may develop as a granulomatous inflammation. b. it may be caused by persistent infections such as tuberculosis. cc. it may occur with autoimmune diseases such as rheumatoid arthritis. 4, large numbers of macrophages are found in the infitrate. e, lymphocytes and eosinophils are rarely involved in its development, wv. pebe cindex pple i307," Irnteveart, e926 im anoserine Print 13 Which of the following enzymes catalyzes the synthesis of DNA from viral RNA? a. Reverse transcriptase b. DNA polymerase cc. RNA polymerase 4. Endonuclease ‘e. Aminoacyl-tRNA synthetase 14 Of the essential transition metal ions found in the human body, the one present at highest overall concentration is: ‘a. copper, b. cobalt. ©. iron, 4d. manganese. e. zine. 15 The optic disk is also called the: a. blind spot b. cornea. °. iris. 4. pupil , macula lutea. 16 Which of the following is characterized as an autoimmune disorder? a. Alzheimer's disease b. Systemic Lupus Erythematosus ©. Osteoarthritis 4d. Parkinson's disease ©. Paget's disease 17 Apregnant female presents with a prescription for an antibiotic for treatment of a urinary tract infection. She tells the pharmacist that she doesn't know why the doctor gave her the medication, because she isn't experiencing any symptoms. Her presentation is consistent with which of the following diagnoses? a, Cystitis b, Septicemia cc. Urinary retention 4, Pyelonephritis . Asymptomatic bacteriuria 18 In cardiovascular physiology, LaPlace’s law relates the tension achieved in a blood vessel wall to: Ithe length of the vessel. Iithe radius of vessel. II the intraluminal pressure. a.lonly b. tllonly ¢, land Il only 4. land Ill only e.|, land il PHARMACEUTICAL SCIENCES 19 Correct statements regarding reversed-phase high-performance liquid chromatography include Which of the following? IThe stationary phase is hydrophobic. I The mobile phase is polar. ll The compound to be separated is very polar. a lonly nw pebe.calindex phpii_a/3074a_eprnttruetart_i’3126.him ane