Insight in Schizophrenia - A Review

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Curr Psychiatry Rep (2010) 12:356–361

DOI 10.1007/s11920-010-0125-7

Insight in Schizophrenia: A Review


Marjorie Baier

Published online: 8 June 2010


# Springer Science+Business Media, LLC 2010

Abstract About 30% to 50% of people with schizophrenia illness is ongoing, and awareness of the symptoms and their
experience lack of insight, meaning they may not acknowl- consequences.
edge their illness or the need for treatment. Researchers During the past decade, the definition of insight has
have developed valid tools for measuring insight. Accord- evolved, and new interventions to improve insight and
ingly, a great deal of descriptive and correlational research functioning have emerged. Recent literature addresses the
has been done on insight, treatment adherence, symptom cultural context of insight and reports the meaning and
severity, and other associated variables. Several possible experience of insight to the patients themselves. The
etiologic models and treatment modalities for lack of progression of knowledge about insight can be seen in the
insight have been proposed. Possible brain dysfunctions movement from expert opinion literature and descriptive
causing lack of insight are being investigated. Cognitive- research to case-control studies and the increasing appear-
behavioral therapy and motivational interviewing have been ance of randomized controlled trials.
successful in teaching patients to cope with the symptoms This review of recent evidence about insight in schizo-
and make changes in health-related behaviors. Ultimately, phrenia begins with the most frequently accepted defini-
people with schizophrenia need to know how to ask for tions of insight, theories about the etiology of lack of
help with coping with their symptoms. insight, and findings from systematic reviews of descriptive
research about the clinical correlates of insight. It chrono-
Keywords Insight . Schizophrenia . Awareness logically follows with more recent theories and perspectives
on insight. Two promising interventions for improving
coping and treatment adherence conclude the review.
Introduction

Insight contributes to recovery from schizophrenia. How- Definition of Insight


ever, 30% to 50% of people with schizophrenia lack
insight, and their mental health providers are unsuccessful It is generally believed that when an individual with
in helping them gain an awareness of their illness [1]. schizophrenia can acknowledge the illness, accept the
Insight is a multidimensional concept with various defi- need for medication, and ask for help when necessary, he
nitions and corresponding measuring tools. Most of the or she has reached a turning point in the illness. Although
definitions of insight include awareness that one has a appropriate medication is an important aspect of success-
mental illness that requires treatment, awareness that the ful treatment, one of the most familiar obstacles to
treatment is refusal to take medications, caused by lack
of insight, denial of illness, delusions, side effects of the
M. Baier (*) medications, and a poor relationship with mental health
School of Nursing, Southern Illinois University Edwardsville,
professionals. Crucial to rehabilitation is the person’s
1660 Cobblestone Creek Drive,
Florissant, MO 63031-4374, USA ability to report early signs of relapse based upon the
e-mail: mbaier@siue.edu person’s insight.
Curr Psychiatry Rep (2010) 12:356–361 357

The DSM considers poor insight an associated feature of cannot assume that the presence of insight improves
schizophrenia that is a manifestation of the illness rather adherence. The positive correlation between insight and
than a coping strategy [2]. Although lack of insight is not treatment adherence does not hold up during the long
listed as a characteristic symptom in the diagnostic criteria, course of a patient’s treatment. Several possible explan-
it is believed to contribute to noncompliance with treat- ations have been proposed for inconsistent relationships
ment, increased risk of relapse and involuntary hospital between later treatment adherence and insight. Although
admissions, poorer psychosocial functioning, and poorer insight may be necessary for adherence, additional factors
prognosis [2]. may be necessary. The cost of the medication; difficulty
Insight for a person with schizophrenia is a multidimen- getting prescriptions and refills; and unpleasant side
sional construct; many clinical scales provide a reliable and effects, such as weight gain and extrapyramidal and
valid assessment of insight. However, because one-item sexual side effects, all represent barriers to adherence to
measures of insight have high correlations with more medication regimens, even in the presence of insight. In
detailed scales, Lincoln et al. [1] suggest that a one-item addition, patients without comorbid substance abuse are
measure might suffice for a screening of overall insight. For more likely to comply with taking medication. Additional
example, a single-item numerical rating of a patient’s factors also may be associated with successful medication
insight based on a chart review and semistructured adherence. For example, patients receiving long-acting
interview would ask the evaluator to assign a rating from injectable antipsychotics or patients who are part of
1 to 7 of the “subject’s awareness of his or her psychiatric assertive community treatment programs could be adher-
symptoms, his or her need for treatment, and the con- ent without having insight [1].
sequences of the disorder” [3].
On the other hand, multiple-item scales allow research-
ers to draw conclusions about specific aspects of insight. Insight and Symptom Severity
One 11-item scale, the Insight and Treatment Attitudes
Questionnaire, measures whether the hospitalized patient Greater insight is associated with less positive and
knows that he or she has an illness that affects mental negative symptoms, according to a meta-analysis of 40
functioning, led to the hospitalization, was ongoing, and published studies of insight and schizophrenia [9]. This
required medication to ameliorate the symptoms [4]. The contrasts with a more recent systematic review that
20-item Scale to Assess Unawareness of Mental Disorder concluded that no study has used a suitable design to
assesses the “current and retrospective awareness of having allow the researcher to draw conclusions about predicting
a mental disorder, the effects of medications, the conse- the relationship between insight and severity of symptoms
quences of the mental disorder, and the specific signs and [1].
symptoms” [5]. Prevalence of no to low partial insight,
measured recently by the Scale to Assess Unawareness of
Mental Disorder in a sample of 101 patients, ranged from Insight and Functional Outcome
56% to 67% [6•].
Recent refinements of the definition reflect new under- Various studies have measured functional outcome as
standings of the global sense of insight. Self-stigma is a general level of functioning, work behavior, or social
force to be encountered by a person with insight deficits. functioning. Based on a systematic review of 18 studies,
The power of hope in recovery is acknowledged by the Lincoln et al. [1] concluded that insight is not related to
definition of “usable insight” as insight that allows the present functioning but influences improvements in
individual to differentiate personal identity from the mental functioning over time. An explanation proposed by the
illness and thereby maintain hope [1, 7]. authors is that symptom severity likely influences the
Theorists considering higher-level cognitive processes long-term relationship between insight and functional
related to insight refer to “cognitive insight” as opposed to outcome [1].
the traditionally understood “clinical insight.” Cognitive
insight refers to metacognition, the ability to examine
distorted views and to revise them [8]. Insight and Aggressive Behavior

Research findings do not consistently support a causal


Insight and Treatment Adherence relationship between insight and violence. This finding
contradicts the intuitive view of some experts that medica-
Although a clear association exists between insight and tion adherence and substance abuse influence the relation-
treatment adherence during the treatment phase, one ship of violence and insight [1, 10].
358 Curr Psychiatry Rep (2010) 12:356–361

Insight and Depression see us. Autistic individuals have difficulty in this area, and
it is suspected that this may contribute to lack of insight in
A small positive relationship between insight and depres- schizophrenia as well.
sive symptoms could be cause for concern. However, a Based on the assumption that lack of insight is neurolog-
cause-and-effect relationship cannot be inferred [1, 9]. It is ically based, treatment would focus on the symptoms and not
possible that increasing awareness of a mental illness and the illness. The mental health professional would have more
its effects on one’s life could result in feelings of success in securing treatment adherence by not trying to
worthlessness and hopelessness. On the other hand, experts convince the patient that he or she is sick. In this view, insight
in the field suggest that having a higher level of depression cannot be successfully forced upon a patient who does not
could result in more accurate self-evaluations [1, 5]. comprehend that he or she is ill [11, 18].
Furthermore, the relationship of insight to depression and There is no universal agreement that lack of insight is
suicide has not been supported in research findings [1]. neurologically based, however. The authors of a recent review
concluded that more research is needed before we can reach a
solid conclusion about anosognosia of schizophrenia [19•].
Causes of Poor Insight A long-held divergent view of the cause of poor insight
holds that psychological defenses protect a person from
Amador and Kronengold [5] maintain that neuropsycho- experiencing distress and hopelessness by unconsciously
logical deficits due to frontal lobe dysfunction are at the not acknowledging the illness. This view is more intuitive
root of poor insight that persists over time. They further than research based. In addition, it is not supported by the
maintain that insight deficits are the equivalent of having American Psychological Association’s DSM-IV-TR, which
anosognosia for schizophrenia. This parallels views of other takes the position that insight is a symptom and not a
experts who suggest that anosognosia or unawareness of a coping mechanism [16•, 19•].
neurological disorder is the cause of lack of insight [11]. Nevertheless, one would expect that a combination of
Anosognosia causes patients to be unable to be aware of etiologic theories might explain the nature of insight in
their illness signs and symptoms. schizophrenia. No single theoretical etiology has predom-
Anosognosia is present in other nervous system disor- inant research support. Because insight is a multidimen-
ders such as Alzheimer’s disease, Parkinson’s disease, sional construct, it is unlikely that there would be a single
Huntington’s disease, and traumatic brain injury [12]. By cause or treatment [20].
comparison with these other brain disorders, it becomes
clear that lack of awareness, anosognosia, is not a circum-
scribed concept. That is, people with schizophrenia may Insight Versus Health Beliefs
have insight for some aspects of their illness, symptoms,
and treatment, but not others [13]. Health beliefs are cognitions that are shaped partially by
Researchers have studied awareness of neurocognitive social and cultural factors. These subjective beliefs do not
symptoms, including deficits in the areas of attention, necessarily correspond with medical theories. For this
memory, and critical thinking, and compared this aware- reason, a person’s beliefs about health and illness need to
ness with insight for psychotic symptoms. A recent study be considered [21].
found that there were differences between awareness of Using the Illness Concept Scale, which covers the basic
neurocognitive symptoms and awareness of clinical dimensions of the Health Belief Model and the Health Locus
symptoms. In a sample of 71 people with schizophrenia, of Control to measure health beliefs, researchers found in one
70% had full insight into their clinical symptoms, but only study of 61 patients that poor insight and health beliefs were
27% had full insight into their neurocognitive symptoms. not related. For this reason, although lack of insight might
Perhaps people with schizophrenia find it more difficult to change with improvement in psychopathology, the dysfunc-
maintain perspective on their cognitive symptoms than tional beliefs toward the illness would not necessarily change.
their clinical symptoms. If patients understand that they The dysfunctional health beliefs would need to be addressed
have cognitive deficits in areas such as memory, attention, by psychological methods that change health behaviors, such
or critical thinking, they could engage in cognitive as motivational interviewing (MI) [21, 22].
remediation [6•, 8, 13–15].
Taking neurocognitive deficits a step further, a rather
complex theory focuses on impairments in metacognition Insight and Cultural Context
[16•, 17]. Metacognition refers to the ability to adopt the
“mental perspective of another toward circumstances of Cultural, social, and interpersonal factors undoubtedly
one’s own mental health” [16•] or to see ourselves as others influence insight [19•, 23]. The meaning that one attaches
Curr Psychiatry Rep (2010) 12:356–361 359

to symptoms and their effect on the person’s life vary. The therapist. Patients were informed that their ratings would
difference can be as broad as international differences and not be shared with the therapists. At the same 3-week point
as narrow as differences in perspective between patient and in time, therapists completed a parallel questionnaire about
provider [19•]. For example, the consumer model of their view of the therapeutic alliance. The patients’ and
recovery views assessment of insight by a clinician as therapists’ views of the alliance were not correlated with
potentially paternalistic unless such assessment is addressed each other, and the patients considered the therapeutic
as a component of a partnership. The consumer model alliance stronger than did the therapists. Patients with
would explore reasons for noncompliance before attributing greater insight rated the alliance more strongly [26].
it to the consumer’s poor judgment or lack of insight [24]. Because the study was correlational, the direction of a
The definition of illness is anchored in one’s culture. A cause and effect does not appear. Intuitively, a therapeutic
qualitative study illustrates this point well. Fifteen residents alliance would positively influence insight. At the same
of a supervised living setting for severely mentally disabled time, increased insight would allow the patient to achieve
individuals were interviewed to determine their self- maximum benefit from the interpersonal therapy.
perceptions [25]. Two thirds perceived themselves as Very little experimental research has been conducted to
mentally well, one self-identified as mentally ill, and the determine if antipsychotic or antidepressant medications
remaining four were uncertain whether they were mentally improve insight. Perhaps new medications not yet on the
ill or well. When asked about the criteria they used to market would enhance metacognition [27, 28]. This is an
determine their own mental health, three reported “being area for further research.
mentally balanced and having a clear mind,” and six cited
varying physical characteristics as contributing to their
mental health status. One cited the ability to work and New Treatments for Impaired Insight
another cited having money as a criterion for mental health.
Apparently for these people, having the diagnosis of mental Two innovative, nonpharmacologic treatment models for
illness was different from being mentally ill at the time of schizophrenia emerging in the past 10 years include CBT
the interview. No firm conclusion could be drawn that the for psychosis [1, 8, 29, 30] and MI [20, 22, 28]. Both use
people interviewed accepted or did not accept their illness. strategies that achieve behavior change and improve coping
with psychotic symptoms (Table 1).
Cognitive therapy for depression is based on examina-
Recovery From Illness tion of thought processes for their accuracy and for negative
emotional reactions to distorted thinking [31, 32]. Distorted
The quality of the therapeutic alliance with the patient is thinking leads to feelings of depression. When the thought
associated with the patient’s level of insight. Eighty patients processes are carefully analyzed within the safety of a
with psychotic symptoms who were part of a larger study of therapeutic relationship, flaws are identified and corrected.
cognitive-behavioral therapy (CBT) completed question- CBT begins with engaging the patient, developing a
naires at the end of 3 weeks about their alliance with their problem list, and setting a goal. The therapist then
Table 1 Comparison of inter-
ventions for impaired insight Motivational interviewing [22]
•Developed to promote behavior change for people with alcohol addiction
•Aims for patient-centered, directive, empathic approach
•Focuses on ambivalence and its resolution
•Uses reflective listening, directing questions
•Depends on internal motivation of the patient
•Establishes rapport by avoiding arguments
•Encourages patient to express the arguments for change
Cognitive-behavioral therapy [31, 32]
•Developed for treatment of depression by engaging patient collaboratively
•Aims for questioning of patient’s thoughts and beliefs
•Focuses on the role of faulty beliefs, threat-related stimuli, and biased information processing
•Uses therapeutic alliance based on patient’s perspective
•Avoids persuasion or forceful arguments
•Avoids labeling symptoms, instead reduces impact of symptoms
•Helps patient generate alternate explanations for symptoms
360 Curr Psychiatry Rep (2010) 12:356–361

questions the patient to discover distortions in thoughts and Finally, an intervention for recovery of insight men-
assumptions. tioned in the literature in conjunction with metacognition is
When using CBT with a patient with schizophrenia, the cognitive remediation, or cognitive enhancement. This
therapist identifies misattributions that occur in relation to includes strategies that stretch one’s thinking, such as
hallucinations and delusions. The emphasis is on the divergent thinking exercises, recognition, and comparison
distress caused to the patient by the meaning he or she tasks to improve memory and information processing, and
places on the symptoms. Stigma is also addressed in CBT computer software programs to improve attention deficits
with patients with schizophrenia as negative beliefs to be and disordered thinking [11].
normalized. The purpose of CBT for people with schizo-
phrenia is to allow the patient to understand and cope with
the psychotic symptoms. Conclusions
Research support exists for the success of CBT for
individuals with schizophrenia. Randomized controlled Lack of insight is a symptom of schizophrenia that has been
trials have shown the efficacy of CBT and sustained defined and measured in descriptive and correlational
benefits over time when the outcomes are alleviating studies. An individual with schizophrenia who has insight
distress and relapse prevention. CBT can improve func- can acknowledge the presence of a mental illness that
tioning without directly reducing symptoms. However, requires treatment and is aware that relapses can occur.
when the outcome variable is medication adherence rather Insight is correlated with treatment adherence. Therefore,
than coping with symptoms, research findings offer less interventions to promote insight or coping with the
support for CBT. Moreover, no evidence indicates that CBT symptoms are crucial. The social and cultural context of
increases insight; focusing on insight is counter to the insight influences insight. Insight is a multidimensional and
theoretical underpinnings of CBT [31, 32]. complex concept. There is not yet universal agreement
MI, which grew from the field of addictions counseling, about the cause of lack of insight or the most successful
focuses on health beliefs and behavior change. The five treatment to promote insight. Two new strategies are
principles of MI that contribute to its success with this beginning to be used: CBT for psychosis and MI.
population are as follows: 1) express empathy, 2) develop
discrepancy, 3) avoid argumentation, 4), roll with resis-
tance, and 5) support self-efficacy [33]. Recognizing again
Disclosure No potential conflict of interest relevant to this article
that the patient’s lack of insight is resistant to change, one was reported.
does not argue or coax.
The decision-making tasks associated with MI may
require modification when used with individuals with
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• Of importance
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