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PEDIA Immunizations 2018
PEDIA Immunizations 2018
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Childhood lmmunizati a Schedule 2018
AGE IN BIRTH MONTHS YEARS
22 )1214161820 46 8l0t2t4
BCG icG
Hep B lep
Het
(DTwP - Hib
- Hep B.) and
other DTaP Tdap/Td
combinations DTaP-IPV-HiB
rPVIOPV-
PCV-
lnfluenza
Measles
Hep A
HPV
DISCLAIMER:
The Childhood lmmunization.Schedule presents recomlnendalions lor immunization lor children and ad0lescents based on updaled lileratule review, experience
and premises current at the time ol.publication. The PPS, PIDSP and PFV acknowledge thal individual circumstances may werranl a decision dillering lr'om the
recommendalions given here. Physicians musl Ieqularly update their knowledge about specific vaccines and their use because inlormation aboul salety and
etlicacy ol vaccines and rec0mmendations relative to their administration conlinue to develop aller a vaccine is licensed.
ANNOTATIONS
Bacille Calmette-Gu6rin (BCG) . Children 6 months to 8 years recetving influenza vaccine for the 1st time
. Given intradermally (lD) should receive 2 d0ses separated by at least 4 weeks
. The dose of BCG is 0.05 ml for children < 12 months of age and 0.1 mlfor . l{ only one dose was given during the previous influenza season. give 2 doses
chi dren > 12 months ol age of the vaccine then one dose yearly thereafter
. Given at the earliest possible age after bifih preferably within the first 2 . Children aged 9 to 1 8 years should recetve one dose of the vaccine yearly
months of life . Annual vaccination should begin tn February but may be given throughout the
. For healthy infants and children > 2 months who were not given BCG at birth, year
PPD prior to BCG vaccination is not necessary. However, PPD is
recommended prior to BCG vaccinati0n if any of the following is present: Measles Vaccine
-
Congenital TB . Given subcutaneously (SC)
- History of close c0ntact to known or suspected infectious TB cases . Given at the age of 9 months, but may be given as early as 6 months of age in
- Clinical findings suggestive of TB and/or chest x-ray suggestive of TB cases 0f outbreaks as declared by public health authorities
ln the presence of any of these conditions, an induration of > 5mm is considered . lf monovalent measles is not available, IVIIVR may be given
positive and BCG is no longer recommended.
Japanese Encephalitis Vaccine (JE)
Hepatitis B Vaccine (HBV) . Given subcutaneously (SC)
. Given intramuscularly (llVl) . Given at a minimum age of 9 months
. Administerthe first dose of monovalent HBVto all newborns >2kgs within 24 . Children I months to 17 years of age should receive one primary dose
hours of life. followed by a booster dose 1 2-24 months after the primary dose
. A 2nd dose is given 1 -2 months after the birth dose . lndividuals 1B years and older should receive a single dose only
. The final dose is administered not earlier than 24 weeks of age. Another dose
is needed if the last dose was given at age <24 weeks, Measles-Mumps-Rubella (MMR) Vaccine
For infants born to HBsAg (+) mothers: . Given subcutaneously (SC)
. Administer HBV and HBIG (0.5m1) within 12 hours of life. HBIG should be . Given at a minimum age of 12 months
administered n0t laterthan 7 days of age if not immediately available. . 2 doses of t\4lt/R vaccine are recommended
For inlanls born to mothers with unknown HBsAg slatus: . The 2nd dose is usually given from 4-6 years of age but may be given at an
. with birth weight >2kgs, administer HBV within 12 hours of birth and earlier age with a minimum of 4 weeks interval between doses.
determine the mother's HBsAg as s00n as possible. lf HBsAg (+). administer
also HBIG not later than 7 days of age, Varicella Vaccine
. with birlh weight <2kgs, administer HBIG in addition to HBV r,lthin I2 nours . Given subcutaneously (SC)
of life. . Givcn at a minimrrm enc nf '1 2 monthq
F3.:--t. t:t'.: -.1
- All recommended PCV doses should be given prior to ppSV23 if possible. . lndicated for those at high risk for invasive disease:
The two vaccines should not be co-administered. lf a dose of ppSV23 is Persistent complement comp0nent deficiencies (including those with inherited
inadvertently given earlier than the recommended interval, the dose need or chronic de{iciencies in C3, C5-9, properdin, factor D, factor H), anatomic/
not be repeated functional asplenia (including sickle cell disease), HlV, travelers to or
- The following tables summarizes the indication and schedule of pCV/ppSV resident of areas where meningococcal disease is hyperendemic or epidemic.
administration to children with high risk conditions according to age group: including countries in the African meningitis belt or the Hajj, or belonging to
a defined risk group during a community or institutional meningococcal-
SCHEDULE OF PCV 13-PPSVz3
INDICATION outbreak
VACCINATION SEOUENCE
Dosing schedule:
Age: 24 mos to 5 years .Ghronic heart disease, particularly
.Administer 1 dose of PCV13 if any .l\4CV4-D: minimum age is g months. For children g-23 m0nths give
cyanotic congenital heart disease and 2 doses 3
incomplete schedule of 3 doses of cardiac failure
months apart. For children 2 years and above give one dose, except in cases
PCV13 was received previously. .Chronic lung disease, including asthma if of asplenia, HIV and persistent complement c0mponent def iciency where 2
.Administer 2 doses of PCV13 at least treated with high-dose oral corticosteroid doses, 8 weeks apart are recommended.
8 weeks apart if unvaccinated or any therapy .lVCV4-TT given t0 children 12 months and above as a
single dose
incomplete schedule of fewer than 3 .Diabetes mellitus . N/lCV4-CRIVI given to children 2 years and above as a single dose
doses of PCV1 3 was received .Cerebrospinal f luid leaks . Revaccinate with a N/CV4 vaccine every 5 years as long as the person remains
previo usly. .Cochlear implant(s)
.The minimum interval between doses at increased risk of infection
.Sickle cell disease and other
. Co-administration of lVlCV4 and other vaccines
of PCVl3 is 8 weeks. hemaglobinopath ies
.For children with no historv of .Congenital or acquired asplenia, or l\,1CV4-D and PCVI3
PPSV23 vaccination, adm inister splenic dysfunction - lf lvlCV4-D is administered to a child with asplenia (including sickle cell
PPSV23 at least B weeks after the .HlV infection disease) 0r HIV infecti0n, do not administer N/CV4-D until age 2 years and
most recent dose of PCV1 3. .Chronic renal failure and nephrotic at least 4 weeks after the completion of all pCV13 doses
sVndrome IVCV4-D and Tdap
.Diseases associated with treatment with
Age:6yrstolSyears - lf [/CV4-D is to be administered to a child at high risk for meningococcal
.Administer 1 dose of PCV13 if they have immunosuppresive drugs or radiation disease, it is recommended that IVCV4-D be given either before oratthe
not previously received this vaccine, Ihelapy, including malignant neoplasms, same time as DTaP.
leukemias, lymphomas, and Hodgkin
regardless of whether the previous vac- IVICV4-TT with Tetanus toxoid (TT) containing vaccines
disease; or solid organ transplantation
cine received was PCVT or PPSV 23 .Congenital immunodeficiency (includes - Whenever feasible, IVICV4-TT should be co-administered with TT-
Children aged 2 years to 64 years old, with containing vaccines, or administer [/CV4-TT 1 month before the other
B- (humoral) or T-lymphocyie'deficiency,
any 1 of the listed chronic medical TT- containing vaccines
complement deficiencies (particu
conditions should get 1 dose of PPSV23
larly Cl , C2, C3, and C4 deficiencies),
and phagocytic disorders (excluding Rabies Vaccine
chronic granulomatous didease) . Given intrarnuscularly (llVl) or intradermally (lD)
. Recommended regimens for pre-exposure prophylaxis:
-:-0 ar!':::'C a-a-, -Working with HAV infected primates or with HAV in research laboratories,
. Ci c'.r aEec I 2-59 nontIs -With clotting factor disorders and chronic liver disease
- !n i-nTirr. tac- 0r,',,:h oie ! b .acc ne csse rec:',:O lefo': age'1 :
.noT11S. E ,, e 2 aca t c'ra coses B .'',eeks apad Human Papillomavirus Yaccine (HPV)
!t/ tn > 2 H c r'acc ne doses rece r,'ed berore aEe 12 rnorths glre l
. Given intramuscularly (lM)
- . Give 3 doses of HPV vaccine following the 0, 1-2, and 6 month schedule,
acdit ona Ccse
. For chlldren < 5 ljears 0 d i,'ho rece led a l-llb',acc ne dOse(sl during or t'iith n regardless of age at vaccine initiation to the following:
14 days of starting chem0therapy or rad ati0n treatment. repeat the dose(st of - Children with history ol sexual abuse or assault starting at age 9 years
H b',accine at east 3 m0nths afler complet 0n 0f therap]' - lmmunocompromised children including those with HIV infection
. For ch dren',','h0 are nematopoet c stem ce itransplant recipients . HPV vaccination is not recommended during pregnancy. lf HPV vaccine
t
re\.'accination uith 3 doses 0f b vacc n0 Q 're 0 '1 ''reeks aparl start ng 6-12 is inadvertently given during pregnancy, delay the remaining doses until after
m0nths after transplant. ls recommended regardless o{ l'accinatlon histol" pregnancy. Pregnancy testing is not necessary before initiating HPV
. Unimmunrzed- children > l5 months 01 age and undergoin0 elective vaccination.
splenect0rny shou d be given 1 dose of Hrb-containing \'/accine at east l4 days
before the procedure Dengue Yaccine
. Unimmunized- chiLdren 5-18 years old and .'','ith either anatomic or iunct ona -Recommendation under review, pending re-labelling of the product
asplenia (lnc uding s cke cell d seasel or HIV n{ect0n should be glven 1
dose of Hib vacclne
' lJninmunized children are those vtithout a primary serres and booster dose or
those v/ithout at least lne dose of the vaccine after 1 4 months of age