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Sugar Glider Mosaic Longitudinal Study PDF
Sugar Glider Mosaic Longitudinal Study PDF
Some basics…
• In the nucleus of each cell, humans
have 23 pairs of chromosomes – a
total of 46
• Offspring will randomly inherit half
of each chromosome from their
mother, and half from their father
Human Father • For each observable trait, an
organism inherits 2 alleles (2
variations that make up a gene)
50% of genes come from the
mother, and 50% come from the
father
Understanding
Gene Inheritance
Dominant: Only one allele is needed to show observable trait (phenotype)
Recessive: Two alleles are needed to show observable trait (phenotype)
Homozygous: Remember:
b Two of the same One half comes
B from each parent
alleles inherited
Heterozygous:
Two different
alleles inherited 2 alleles = 1 Mom’s Dad’s
gene half half
Chromosome
Genotype Phenotype
The genetic makeup Physical, observable expression of genotype
(color/pattern in our case)
mm In theory… Non-mosaic
Same phenotype,
Mm different genotype! Mosaic
MM Mosaic
DOMINANT GENES
Mosaic (Mm) – a dominant gene
(Based on empirical evidence)
Mosaic Father
Non-mosaic Mother
M = Abnormal
gene (Mosaic Mosaic Non-mo
Mosaic
Non-mo
m = Normal
gene
Mosaic Non-mo
Non-mosaic Mother
Mosaic Mother
Merle
gene in
Australian
Shepherds
So how can we prove this?
If MM is lethal, then
rather than produce a 3:1
(75%) mosaic offspring,
mosaic x mosaic pairings
hypothetically will result
66% in a 2:1 (66%) ratio of
33% mosaic to non-mosaic
offspring.
Why not just use the database?
Sparrow
Credit: Tyler Cleckley,
Shelley S.
Kaleidoscope
Credit: Priscilla Price
Sometimes, gliders can powder pied (progressive pieds)
Pixie
Diamond as an adult
Possible candidate genes?
• Vitiligo gene
• Chinchilla/silvering gene
• G locus “graying gene” (what turns gray horses white)
Silvering Gene
Gray at 4 years old